Gold nanoparticles/two-dimensional (2D) hexagonal boron nitride nanosheets including diethylstilbestrol imprinted polymer: Electrochemical detection in urine samples and validation

A new diethylstilbestrol (DES) imprinted sensor approach based on gold nanoparticles (AuNPs) incorporated two-dimensional (2D) hexagonal boron nitride (2D-hBN) nanosheets was presented for DES detection. The methods such as scanning electron microscope (SEM), transmission electron microscope (TEM), X-ray photoelectron spectroscopy (XPS), X-ray diffraction (XRD) method, cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) were used for all nanomaterials’ characterizations. DES imprinted sensor was prepared in presence of 100.0 mM pyrrole containing 25.0 mM DES by CV. The developed method was validated and 5.0 x 10-12−1.0 x 10-8 M and 1.0 x 10-13 M were founded as the linearity range and the detection limit (LOD). DES imprinted glassy carbon electrode (GCE) was applied in presence of the natural estrogens such as estrone (E1), estradiol (E2) and estriol (E3) and the other agents such as hydroquinone (HYD) and catechol (CAT). © 2018 The Electrochemical Society

Gold nanoparticles/two-dimensional (2D) hexagonal boron nitride nanosheets including diethylstilbestrol imprinted polymer: Electrochemical detection in urine samples and validation

A new diethylstilbestrol (DES) imprinted sensor approach based on gold nanoparticles (AuNPs) incorporated two-dimensional (2D) hexagonal boron nitride (2D-hBN) nanosheets was presented for DES detection. The methods such as scanning electron microscope (SEM), transmission electron microscope (TEM), X-ray photoelectron spectroscopy (XPS), X-ray diffraction (XRD) method, cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) were used for all nanomaterials’ characterizations. DES imprinted sensor was prepared in presence of 100.0 mM pyrrole containing 25.0 mM DES by CV. The developed method was validated and 5.0 x 10-12−1.0 x 10-8 M and 1.0 x 10-13 M were founded as the linearity range and the detection limit (LOD). DES imprinted glassy carbon electrode (GCE) was applied in presence of the natural estrogens such as estrone (E1), estradiol (E2) and estriol (E3) and the other agents such as hydroquinone (HYD) and catechol (CAT). © 2018 The Electrochemical Society

Development of molecular imprinted sensor including graphitic carbon nitride/N-doped carbon dots composite for novel recognition of epinephrine

The presence of epinephrine is crucial factor relating to several chronic diseases such as hypertension and myocardial infarction. Due to these significant problems, electrochemical recognition based on graphitic carbon nitride/N-doped carbon dots composite (g-C3N4/NCDS) and molecularly imprinted polymer was presented for epinephrine detection in this study. Fourier-transform infrared spectroscopy, scanning electron microscope, transmission electron microscope, x-ray diffraction method and electroanalytical methods such as electrochemical impedance spectroscopy and cyclic voltammetry were performed for characterizations of nanomaterials. After that, epinephrine imprinted voltammetric sensor on graphitic carbon nitride/N-doped carbon dots composite was carried out in presence of 100.0 mM pyrrole containing 25.0 mM epinephrine via cyclic voltammetry. Epinephrine imprinted electrode showed high sensitivity for epinephrine recognition in wide linear range of 1.0 × 10−12 - 1.0 × 10−9 M and detection limit (LOD) of 3.0 × 10−13 M. Epinephrine imprinted sensor was applied to urine samples for epinephrine analysis. © 2019 Elsevier Lt

Development of cardiac troponin-I biosensor based on boron nitride quantum dots including molecularly imprinted polymer

The cardiac Troponin-I (cTnI) is one of the subunits of cardiac troponin complexes and a pivotal biochemical marker of acute myocardial infarction (AMI). Due to its myocardial specificity, cTnI is widely used for the diagnosis of AMI diseases. In this study, a novel imprinted biosensor approach based on boron nitride quantum dots (BNQDs) was presented for cTnI detection in plasma samples. Various characterization methods such as scanning electron microscope (SEM), transmission electron microscope (TEM), x-ray diffraction (XRD), cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) were used for all characterizations of nanomaterials. After the characterization analysis, cTnI imprinted electrode was developed in the presence of 100.0 mM pyrrole containing 25.0 mM cTnI. After that, the analytical studies of cTnI in plasma samples were performed by using cTnI imprinted biosensor. The results of the study have revealed that 0.01–5.00 ng mL −1 and 0.0005 ng mL −1 were found as the linearity range and the detection limit (LOD). Moreover, the selectivity of cTnI imprinted glassy carbon electrode (GCE) was investigated for plasma sample analysis in the presence of other nonspecific and specific proteins including cardiac myoglobin (MYG), bovine serum albumin (BSA) and cardiac troponin T (cTnT), respectively. Furthermore, the prepared biosensor was examined in terms of stability, repeatability, reproducibility and reusability. Finally, the imprinted biosensor was applied to the plasma samples having high recovery. © 2018 Elsevier B.V

Electrochemical Sensor Based on Au@nitrogen-Doped Carbon Quantum Dots@Ag Core-Shell Composite including Molecular Imprinted Polymer for Metobromuron Recognition

Electrochemical recognition based on Au@nitrogen-doped carbon quantum dots@Ag core-shell (Au NPs@NCDS@Ag NPs) composite including molecular imprinted polymer (MIP) was presented for metobromuron (MBN) detection. Firstly, novel triple-layered core-shell structure including gold nanoparticles core, nitrogen-doped carbon quantum dots interlayer and silver nanoparticles outside shell was synthesized by the reduction of chloroauric acid (HAuCl4), silver nitrate (AgNO3) in the presence of NCDS. Secondly, MBN imprinted polymer on Au NPs@NCDS@Ag NPs composite was electrochemically performed in the presence of pyrrole and MBN via cyclic voltammetry (CV). Fourier-transform infrared spectroscopy (FTIR), transmission electron microscope (TEM), energy-dispersive x-ray (EDX) spectroscopy, x-ray diffraction (XRD) method and electroanalytical methods such as CV, chronoamperometry (CA), electrochemical impedance spectroscopy (EIS) were performed for characterizations of core-shell structure. MBN imprinted electrode showed high electrocatalytic performance and the linear range of 1.0 × 10−12–2.0 × 10−9 M and detection limit (LOD) of 2.0 × 10−13 M were obtained. © 2019 The Electrochemical Society

Determination of rutin by CoFe2O4 nanoparticles ionic liquid nanocomposite as a voltammetric sensor

Rutin is a class of flavonoids. Flavonoids have crucial antioxidant and chelating properties and are present in fruits and vegetables. Despite of their elusive metabolism, the enteric absorption reduces plasma oxidant status. Due to these reasons, rutin detection is important based on sensitive method. In the present report, a new electrochemical sensor based on CoFe2O4 nanoparticles ionic liquid nanocomposite was developed for rutin analysis in orange juice samples. Firstly, the structure analysis of prepared nanocomposites was characterized by transmission electron microscopy, cyclic voltammetry, X-ray photoelectron spectroscopy, electrochemical impedance spectroscopy and energy dispersive X-ray analysis. The linearity range and detection limit of the prepared sensor were obtained as 1.0 × 10− 10–1.0 × 10− 8 and 3.0 × 10− 11 M, respectively. In addition, the voltammetric sensor was applied to orange juice samples with high recovery. © 2017 Elsevier B.V

Molecular imprinting polymer with polyoxometalate/carbon nitride nanotubes for electrochemical recognition of bilirubin

In this work, a new molecular imprinted sensor based on polyoxometalate (H3PW12O40, POM) functionalized carbon nitride nanotubes (C3N4 NTs) nanocomposite was prepared for bilirubin (BR) analysis. The structures of prepared surfaces based on the nanocomposite were characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM), x-ray photoelectron spectroscopy (XPS) and energy dispersive x-ray analysis (EDX). After that, BR imprinted electrode on H3PW12O40/C3N4 NTs nanocomposite was developed by cyclic voltammetry (CV) in 100 mM pyrrole containing 25 mM BR. The linearity range and the detection limit of the developed method were calculated as 1.0 × 10−12–1.0 × 10−10 M and 3.0 × 10−13 M, respectively. In addition, the imprinted sensor was applied to human plasma samples with high recovery and selectivity. © 2017 Elsevier Lt

Enhanced surface plasmon resonance (SPR) signals based on immobilization of core-shell nanoparticles incorporated boron nitride nanosheets: Development of molecularly imprinted SPR nanosensor for anticancer drug, etoposide

An effective SPR nanosensor based on core-shell nanoparticles (Ag@AuNPs) incorporated hexagonal boron nitride (HBN) nanosheets and molecularly imprinted polymer (MIP) was presented for etoposide (ETO) detection. Scanning electron microscope (SEM), transmission electron microscope (TEM), x-ray diffraction (XRD) method, cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), fourier transform infrared (FTIR) spectroscopy and atomic force microscopy (AFM) methods were utilized for all characterizations of nanomaterials and polymer surfaces. ETO imprinted SPR nanosensor based on Ag@AuNPs-HBN nanocomposite was developed in the presence of poly(2-hydroxyethyl methacrylate-methacryloylamidoglutamic acid) [p(HEMA-MAGA)]. The results of the study have revealed that 0.001–1.00 ng mL −1 (1.70 × 10 –12 –1.70 × 10 −9 M) and 0.00025 ng mL −1 (4.25 × 10 –13 M) were found as the linearity range and the detection limit (LOD). Furthermore, the prepared SPR nanosensor was examined in terms of stability, repeatability and selectivity. Finally, the imprinted SPR nanosensor was applied to the urine samples having high recovery. © 2019 Elsevier B.V