Serial case reports: Pregnancy with Lucio’s phenomenon of leprosy in dr. Soetomo hospital, Surabaya

Leprosy is a complex disease which will affect in many aspects of the patient. In dr. Soetomo hospital, there were two cases of pregnancy with leprosy and Lucio’s phenomenon from 2014 until 2018. Both had been receiving multidrug therapy (MDT) before pregnancy but stopped due to lack of compliance. First case was resulted with term. Second case was admitted with worse condition than the first case, fetal growth restriction and ended with preterm delivery probably because the severity of the case. Lucio’s phenomenon incidence is increased in pregnancy due to immunodeficient condition. This serial case report shows that the initial diagnosis and optimum treatment of leprosy is very important especially in women of child-bearing age

Magnesium intoxication in women with preeclampsia with severe features treated with magnesium sulfate

Objective: To evaluate the maternal-neonatal outcome in magnesium (Mg)-intoxicated women with preeclampsia with severe features (PESF) treated with magnesium sulfate (MgSO₄). Methods: A total of 19 Mg intoxicated PESF women (cases) were compared with 166 PESF women without signs of intoxication (controls). Results: Mg serum levels of cases was higher compared to control group (12.36 ± 3.54 mg/dl versus 2.69 ± 0.83 mg/dl). 3 women died and 3 had major maternal morbidity in cases group compared with zero in the control group (P = 0.009). Mg intoxication was also significantly associated with perinatal deaths and low Apgar scores at 1 and 5 minutes. Conclusion: Mg intoxication is associated with a increased risk of maternal and perinatal mortality and morbidity.Muhammad Ilham Aldika Akbar, Daniel Yoseph, Aditiawarman -, Muhammad Adrianes Bachnas, Erry Gumilar Dachlan, Gustaaf Albert Dekker, and Ernawat