83 research outputs found
Status of the GAMMA-400 Project
The preliminary design of the new space gamma-ray telescope GAMMA-400 for the
energy range 100 MeV - 3 TeV is presented. The angular resolution of the
instrument, 1-2{\deg} at E{\gamma} ~100 MeV and ~0.01^{\circ} at E{\gamma} >
100 GeV, its energy resolution ~1% at E{\gamma} > 100 GeV, and the proton
rejection factor ~10E6 are optimized to address a broad range of science
topics, such as search for signatures of dark matter, studies of Galactic and
extragalactic gamma-ray sources, Galactic and extragalactic diffuse emission,
gamma-ray bursts, as well as high-precision measurements of spectra of
cosmic-ray electrons, positrons, and nuclei.Comment: 6 pages, 1 figure, 1 table, submitted to Advances in Space Researc
Polymorphism of the catechol-O-methyltransferase gene in Han Chinese patients with psoriasis vulgaris
Psoriasis vulgaris is defined by a series of linked cellular changes in the skin: hyperplasia of epidermal keratinocytes, vascular hyperplasia and ectasia, and infiltration of T lymphocytes, neutrophils and other types of leukocytes in the affected skin. Catechol-O-methyltransferase (COMT) 158 polymorphism can reduce the activity of the COMT enzyme that may trigger defective differentiation of keratinocytes in psoriasis. Immunocytes can degrade and inactivate catecholamines via monamine oxidase (MAO) and COMT in the cells. We hypothesized that the COMT-158G > A polymorphism was associated with the risk of psoriasis vulgaris in Han Chinese people. In a hospital-based case-control study, 524 patients with psoriasis vulgaris and 549 psoriasis-free controls were studied. COMT-158 G > A polymorphism was genotyped using the PCR sequence-specific primer (PCR-SSP) technique. We found no statistically significant association between the COMT-158 allele A and the risk of psoriasis vulgaris (p = 0.739 adjusted OR = 1.03; 95% CI = 0.81-1.31). This suggests that the COMT-158 G > A polymorphism may not contribute to the etiology of psoriasis vulgaris in the Han Chinese population
Erratum: First observation and amplitude analysis of the B- -> D+K-pi(-) decay [Phys. Rev. D 91, 092002 (2015)]
Recent Updates in Both the Diagnosis and Treatment Options that Impact the Clinical Treatment of Pulmonary Arterial Hypertension
Nonbinding recommendations: the relative effects of focal points versus uncertainty reduction on bargaining outcomes
Bargaining, Experiments, Dispute resolution, Focal points, Arbitration,
Analysis of discontinuous variation in albumin production by hepatoma cells at the cellular level
- …