Methods to assess iron and iodine status

Four methods are recommended for assessment of iodine nutrition: urinary iodine concentration, the goitre rate, and blood concentrations of thyroid stimulating hormone and thyroglobulin. These indicators are complementary, in that urinary iodine is a sensitive indicator of recent iodine intake (days) and thyroglobulin shows an intermediate response (weeks to months), whereas changes in the goitre rate reflect long-term iodine nutrition (months to years). Spot urinary iodine concentrations are highly variable from day-to-day and should not be used to classify iodine status of individuals. International reference criteria for thyroid volume in children have recently been published and can be used for identifying even small goitres using thyroid ultrasound. Recent development of a dried blood spot thyroglobulin assay makes sample collection practical even in remote areas. Thyroid stimulating hormone is a useful indicator of iodine nutrition in the newborn, but not in other age groups. For assessing iron status, haemoglobin measurement alone has low specificity and sensitivity. Serum ferritin remains the best indicator of iron stores in the absence of inflammation. Measures of iron-deficient erythropoiesis include transferrin iron saturation and erythrocyte zinc protoporphyrin, but these often do not distinguish anaemia due to iron deficiency from the anaemia of chronic disease. The serum transferrin receptor is useful in this setting, but the assay requires standardization. In the absence of inflammation, a sensitive method to assess iron status is to combine the use of serum ferritin as a measure of iron stores and the serum transferrin receptor as a measure of tissue iron deficiency

Continuing professional development in learning and teaching for Graduate Teaching Assistants (GTAs): An institutional response

Graduate teaching assistants (GTAs) are being employed in higher education in a number of roles and with a number of responsibilities regarding learning and teaching and enhancing the student experience. This is in addition to their primary role as researcher. Research training is being provided variously at national, university and departmental levels. Support for GTAs’ learning and teaching role and for their further development in this role is often provided in an ad hoc manner at departmental and university levels (though increasingly also through the support of Higher Education Academy subject centres). This paper outlines the approach that a large research-led university has taken to the continuing professional development of its GTAs. This is examined in terms of the initial support provided to GTAs as well as a more advanced level of support, encapsulated in an accredited Masters level course. The paper concludes with a proposal for research into the learning experience of the GTAs as well as for further research which will examine ways in which the university may support a larger number of GTAs in addition to other staff on hourly paid contracts

Instantons of Type IIB Supergravity in Ten Dimensions

A family of SO(10) symmetric instanton solutions in Type IIB supergravity is developed. The instanton of least action is a candidate for the low-energy, semiclassical approximation to the {D=--1} brane. Unlike a previously published solution,[GGP] this admits an interpretation as a tunneling amplitude between perturbatively degenerate asymptotic states, but with action twice that found previously. A number of associated issues are discussed such as the relation between the magnetic and electric pictures, an inversion symmetry of the dilaton and the metric, the $R\times S^9$ topology of the background, and some properties of the solution in an "instanton frame" corresponding to a Lagrangian in which the dilaton's kinetic energy vanishes.Comment: 15 pages, no figures; Version 2 has revised sections IV and V. Earlier equations are essentially unchanged, but interpretation changed, on advice of counse

More on the Narrowing of Impact Broadened Radio Recombination Lines at High Principal Quantum Number

Recently Alexander and Gulyaev have suggested that the apparent decrease in impact broadening of radio recombination lines seen at high principal quantum number n may be a product of the data reduction process, possibly resulting from the presence of noise on the telescope spectra that is not present on the calculated comparison spectra. This is an interesting proposal. However, there are serious problems with their analysis that need to be pointed out. Perhaps the most important of these is the fact that for principal quantum numbers below n = 200, where the widths are not in question, their processed generated profile widths do not fit the widths of the processed lines obtained at the telescope. After processing, the halfwidths of the generated and telescope profiles must agree below n = 200 if we are to believe that the processed generated linewidths above n = 200 are meaningful. Theirs do not. Furthermore, we find that after applying the linewidth reduction factors found by Alexander and Gulyaev for their noise added profiles to our generated profiles to simulate their noise adding effect, the processed widths we obtain still do not come close to explaining the narrowing seen in the telescope lines for n values in the range 200 < n < 250. It is concluded that what is needed to solve this mystery is a completely new approach using a different observing technique instead of simply a further manipulation of the frequency-switched data.Comment: Six pages with 4 figures. Accepted for publication in Astrophysics and Space Scienc

A Finite Element Model of Multi-Layered Laser Sintered Parts

Afinite element heat transfer analysis is applied to the selective laser sinteringofa layered part made frompolyroerpowder. The sinteringsubroutine in the code is based on the analyses of Scherer [l t2] and Mackenzie and Shuttleworth [3]. The density and conductivity of the particle bed are treated as functions of the void fraction of the bed. The Yagi - Kunii [4] thermal characterization of the powder bed is used to calculate the effective conductivity of the bed. An example is worked for ABS powder.Mechanical Engineerin

Dephasing-assisted transport: quantum networks and biomolecules

Original article can be found at: http://www.iop.org/EJ/journal/1367-2630/1 DOI: 10.1088/1367-2630/10/11/113019Transport phenomena are fundamental in physics. They allow for information and energy to be exchanged between individual constituents of communication systems, networks or even biological entities. Environmental noise will generally hinder the efficiency of the transport process. However, and contrary to intuition, there are situations in classical systems where thermal fluctuations are actually instrumental in assisting transport phenomena. Here we show that, even at zero temperature, transport of excitations across dissipative quantum networks can be enhanced by local dephasing noise. We explain the underlying physical mechanisms behind this phenomenon and propose possible experimental demonstrations in quantum optics. Our results suggest that the presence of entanglement does not play an essential role for energy transport and may even hinder it. We argue that Nature may be routinely exploiting dephasing noise and show that the transport of excitations in simplified models of light harvesting molecules does benefit from such noise assisted processes. These results point toward the possibility for designing optimized structures for transport, for example in artificial nanostructures, assisted by noise.Peer reviewe

Gas adsorption in active carbons and the slit-pore model 1 : pure gas adsorption

We describe procedures based on the polydisperse independent ideal slit-pore model, Monte Carlo simulation and density functional theory (a 'slab-DFT') for predicting gas adsorption and adsorption heats in active carbons.A novel feature of this work is the calibration of gas-surface interactions to a high surface area carbon, rather than to a low surface area carbon as in all previous work. Our models are used to predict the adsorption of carbon dioxide, methane, nitrogen, and hydrogen up to 50 bar in several active carbons at a range of near-ambient temperatures based on an analysis of a single 293 K carbon dioxide adsorption isotherm. The results demonstrate that these models are useful for relatively simple gases at near-critical or supercritical temperatures

Simulating fluid-solid equilibrium with the Gibbs ensemble

The Gibbs ensemble is employed to simulate fluid-solid equilibrium for a shifted-force Lennard-Jones system. This is achieved by generating an accurate canonical Helmholtz free-energy model of the (defect-free) solid phase. This free-energy model is easily generated, with accuracy limited only by finite-size effects, by a single isothermal-isobaric simulation at a pressure not too far from coexistence for which the chemical potential is known. We choose to illustrate this method at the known triple-point because the chemical potential is easily calculated from the coexisting gas. Alternatively, our methods can be used to locate fluid-solid coexistence and the triple-point of pure systems if the chemical potential of the solid phase can be efficiently calculated at a pressure not too far from the actual coexistence pressure. Efficient calculation of the chemical potential of solids would also enable the Gibbs ensemble simulation of bulk solid-solid equilibrium and the grand-canonical ensemble simulation of bulk solids

Convergence of linearized and adjoint approximations for discontinuous solutions of conservation laws. Part 2: adjoint approximations and extensions

This paper continues the convergence analysis in [M. Giles and S. Ulbrich, SIAM J. Numer. Anal., 48 (2010), pp. 882–904] of discrete approximations to the linearized and adjoint equations arising from an unsteady one-dimensional hyperbolic equation with a convex flux function. We consider a simple modified Lax–Friedrichs discretization on a uniform grid, and a key point is that the numerical smoothing increases the number of points across the nonlinear discontinuity as the grid is refined. It is proved that there is convergence in the discrete approximation of linearized output functionals even for Dirac initial perturbations and pointwise convergence almost everywhere for the solution of the adjoint discrete equations. In particular, the adjoint approximation converges to the correct uniform value in the region in which characteristics propagate into the discontinuity. Moreover, it is shown that the results of [M. Giles and S. Ulbrich, SIAM J. Numer. Anal., 48 (2010), pp. 882–904] and the present paper hold also for quite general nonlinear initial data which contain multiple shocks and for which shocks form at a later time and/or merge

Selection of efficient hanging ratios of gillnet on fish catch in Lake Kainji, as means of alleviating poverty among artisanal fishermen in Nigeria

Five experimental gillnet each measuring 50mx 3m nylon multi filament netting of 3" by210/2 mesh size were constructed using 40%, 45%, 50%, 55% and 60% hanging percentages, the report was carried out at Yunawa fishing village on the eastern bank of Lake Kainji. The nets were set over night (6 hours approximately). Between April-July 2004, the fish caught by the five nets were recorded taking into consideration the three mode of capture i.e. enmeshing entanglement and wedging Weight number and percentage mean weight and number based on species at five different hanging ratios were analyzed in general 50% hanging ratio was found to be the best followed by 40% among others. There was significant difference (P<0.05) in the mode of capture for both hanging ratios. Most of the fish were caught by entanglement i.e. about 83% of the catch was by entanglement while 505 hanging ratio was the best considered after the report. The occurrence of species of the five hanging ratios has significant difference (P<0.05) in terms of catch by weight and numbe