4 research outputs found
Abstract #4307 Molecular pathways involved in the interferon-alpha model of immune depression
P.485 Imaging brain microglia activation following the peripheral immune challenge Interferon-alpha: A translocation protein study in healthy humans
Abstract # 4264 Glucocorticoid resistance, childhood trauma and antidepressant response in patients with depression: Results from BIODEP study UK
The relationship of personal resources with symptom severity and psychosocial functioning in persons with schizophrenia: results from the Italian network for Research on Psychoses study
The relationships of personal resources with symptom severity and psychosocial functioning have never been tested systematically in a large sample of people with schizophrenia. We applied structural equation models to a sample of 921 patients with schizophrenia collected in a nationwide Italian study, with the aim to identify, among a large set of personal resources, those that may have an association with symptom severity or psychosocial functioning. Several relevant demographic and clinical variables were considered concurrently. Poor service engagement and poor recovery style, as well as older age and younger age at onset, were related to greater symptom severity and poorer social functioning. Higher resilience and higher education were related to better social functioning only. Poor problem-focused coping and internalized stigma, as well as male gender and depression, were related to symptom severity only. The explored variables showed distinctive and partially independent associations with symptom severity and psychosocial functioning. A deeper understanding of these relationships may inform treatment decisions