7,406 research outputs found
Pulse Profiles, Accretion Column Dips and a Flare in GX 1+4 During a Faint State
The Rossi X-ray Timing Explorer (RXTE) spacecraft observed the X-ray pulsar
GX 1+4 for a period of 34 hours on July 19/20 1996. The source faded from an
intensity of ~20 mCrab to a minimum of <~0.7 mCrab and then partially recovered
towards the end of the observation. This extended minimum lasted ~40,000
seconds. Phase folded light curves at a barycentric rotation period of
124.36568 +/- 0.00020 seconds show that near the center of the extended minimum
the source stopped pulsing in the traditional sense but retained a weak dip
feature at the rotation period. Away from the extended minimum the dips are
progressively narrower at higher energies and may be interpreted as
obscurations or eclipses of the hot spot by the accretion column. The pulse
profile changed from leading-edge bright before the extended minimum to
trailing-edge bright after it. Data from the Burst and Transient Source
Experiment (BATSE) show that a torque reversal occurred <10 days after our
observation. Our data indicate that the observed rotation departs from a
constant period with a Pdot/P value of ~-1.5% per year at a 4.5 sigma
significance. We infer that we may have serendipitously obtained data, with
high sensitivity and temporal resolution about the time of an accretion disk
spin reversal. We also observed a rapid flare which had some precursor
activity, close to the center of the extended minimum.Comment: 19 pages, 6 figures, accepted for publication in Astrophysical
Journal (tentatively scheduled for vol. 529 #1, 20 Jan 2000
Radiative recombination data for modeling dynamic finite-density plasmas
We have calculated partial final-state resolved radiative recombination (RR) rate coefficients from the initial ground and metastable levels of all elements up to and including Zn, plus Kr, Mo, and Xe, for all isoelectronic sequences up to Na-like forming Mg-like. The data are archived according to the Atomic Data and Analysis Structure (ADAS) data class adf48, which spans a temperature range of z2(101-107) K, where z is the initial ion charge. Fits to total rate coefficients have been determined, for both the ground and metastable levels, and those for the ground are presented here. Comparison is made both with previous RR rate coefficients and with (background) R-matrix photoionization cross sections. This RR database complements a dielectronic recombination (DR) database already produced, and both are being used to produce updated ionization balances for both (electron) collisionally ionized and photoionized plasmas
Crystal structures of four indole derivatives as possible cannabinoid allosteric antagonists
Acknowledgements We thank the EPSRC National Crystallography Service (University of Southampton) for the data collections and the EPSRC National Mass Spectrometry Service (University of Swansea) for the HRMS data. We thank John Low for carrying out the Cambridge Database survey.Peer reviewedPublisher PD
Electrically tunable selective reflection of light from ultraviolet to visible and infrared by heliconical cholesterics
Cholesteric liquid crystals with helicoidal molecular architecture are known
for their ability to selectively reflect light with the wavelength that is
determined by the periodicity of molecular orientations. Here we demonstrate
that by using a cholesteric with oblique helicoidal(heliconical) structure, as
opposed to the classic right-angle helicoid, one can vary the wavelength of
selectively reflected light in a broad spectral range, from ultraviolet to
visible and infrared (360-1520 nm for the same chemical composition) by simply
adjusting the electric field applied parallel to the helicoidal axis. The
effect exists in a wide temperature range (including the room temperatures) and
thus can enable many applications that require dynamically controlled
transmission and reflection of electromagnetic waves, from energy-saving smart
windows to tunable organic lasers, reflective color display, and transparent
see-through displays.Comment: 11 pages, 5figure
Tau Aggregation Inhibitor Therapy : An Exploratory Phase 2 Study in Mild or Moderate Alzheimer's Disease
ACKNOWLEDGMENTS We thank patients and their caregivers for their participation in the study and are indebted to all the investigators involved in the study, particularly Drs. Douglas Fowlie and Donald Mowat for their helpful contributions to the clinical execution of the study in Scotland. We thank Sharon Eastwood, Parexel, for assistance in preparing initial drafts of the manuscript. We acknowledge constructive comments provided by Professors G. Wilcock and S. Gauthier on drafts of the article. CMW, CRH, and JMDS are officers of, and hold beneficial interests in, TauRx Therapeutics. RTS, PB, KK, and DJW are paid consultants to TauRx Therapeutics. The study was financed entirely by TauRx TherapeuticsPeer reviewedPublisher PD
Ethyl 2-(5-bromo-2-iodoanilino)cyclopent-1-ene-1-carboxylate
Acknowledgements We thank the EPSRC National Crystallography Service (University of Southampton) for the data collection.Peer reviewedPublisher PD
Territorial Tactics: The Socio-spatial Significance of Private Policing Strategies in Cape Town
This paper analyses the policing strategies of private security companies operating in urban space. An existing literature has considered the variety of ways that territory becomes of fundamental importance in the work of public police forces. However, this paper examines territory in the context of private security companies. Drawing on empirical research in Cape Town, it examines how demarcated territories become key subjects in private policing. Private security companies are responsible for a relatively small section of the city, while in contrast the public police ultimately have to see city space as a whole. Hence, private policing strategy becomes one of displacement, especially of so-called undesirables yielding a patchworked public space associated with private enclaves of consumption. The conclusions signal the historical resonances and comparative implications of these political-legal-security dynamics. © 2013 Urban Studies Journal Limited
Cellular Models of Aggregation-Dependent Template-Directed Proteolysis to Characterize Tau Aggregation Inhibitors for Treatment of Alzheimer's Disease
Copyright © 2015, The American Society for Biochemistry and Molecular Biology. Acknowledgements-We thank Drs Timo Rager and Rolf Hilfiker (Solvias, Switzerland) for polymorph analyses.Peer reviewedPublisher PD
Laminar flow of two miscible fluids in a simple network
When a fluid comprised of multiple phases or constituents flows through a
network, non-linear phenomena such as multiple stable equilibrium states and
spontaneous oscillations can occur. Such behavior has been observed or
predicted in a number of networks including the flow of blood through the
microcirculation, the flow of picoliter droplets through microfluidic devices,
the flow of magma through lava tubes, and two-phase flow in refrigeration
systems. While the existence of non-linear phenomena in a network with many
inter-connections containing fluids with complex rheology may seem
unsurprising, this paper demonstrates that even simple networks containing
Newtonian fluids in laminar flow can demonstrate multiple equilibria.
The paper describes a theoretical and experimental investigation of the
laminar flow of two miscible Newtonian fluids of different density and
viscosity through a simple network. The fluids stratify due to gravity and
remain as nearly distinct phases with some mixing occurring only by diffusion.
This fluid system has the advantage that it is easily controlled and modeled,
yet contains the key ingredients for network non-linearities. Experiments and
3D simulations are first used to explore how phases distribute at a single
T-junction. Once the phase separation at a single junction is known, a network
model is developed which predicts multiple equilibria in the simplest of
networks. The existence of multiple stable equilibria is confirmed
experimentally and a criteria for their existence is developed. The network
results are generic and could be applied to or found in different physical
systems
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