868 research outputs found

    Estimating Subjective Probabilities

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    Subjective probabilities play a role in many economic decisions. There is a large theoretical literature on the elicitation of subjective probabilities, and an equally large empirical literature. However, there is a gulf between the two. The theoretical literature proposes a range of procedures that can be used to recover subjective probabilities, but stresses the need to make strong auxiliary assumptions or "calibrating adjustments" to elicited reports in order to recover the latent probability. With some notable exceptions, the empirical literature seems intent on either making those strong assumptions or ignoring the need for calibration. We illustrate how the joint estimation of risk attitudes and subjective probabilities using structural maximum likelihood methods can provide the calibration adjustments that theory calls for. This allows the observer to make inferences about the latent subjective probability, calibrating for virtually any well-specified model of choice under uncertainty. We demonstrate our procedures with experiments in which we elicit subjective probabilities. We calibrate the estimates of subjective beliefs assuming that choices are made consistently with expected utility theory or rank-dependent utility theory. Inferred subjective probabilities are significantly different when calibrated according to either theory, thus showing the importance of undertaking such exercises. Our findings also have implications for the interpretation of probabilities inferred from prediction markets.

    Inferring Beliefs as Subjectively Uncertain Probabilities

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    We propose a method for estimating subjective beliefs, viewed as a subjective probability distribution. The key insight is to characterize beliefs as a parameter to be estimated from observed choices in a well-defined experimental task, and to estimate that parameter as a random coefficient. The experimental task consists of a series of standard lottery choices in which the subject is assumed to use conventional risk attitudes to select one lottery or the other, and then a series of betting choices in which the subject is presented with a range of bookies offering odds on the outcome of some event that the subject has a belief over. Knowledge of the risk attitudes of subjects conditions the inferences about subjective beliefs. Maximum simulated likelihood methods are used to estimate a structural model in which subjects employ subjective beliefs to make bets. We present evidence that some subjective probabilities are indeed best characterized as probability distributions with non-zero variance.

    The influence of risk factors associated with captive rearing on post-release survival in translocated cirl buntings Emberiza cirlus in the UK

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    Population decline resulting from agricultural intensification led to contraction of the range of the cirl bunting Emberiza cirlus in the UK to a small area of south Devon. As part of the UK Biodiversity Action Plan for the species, a project to re-establish a population in suitable habitat in Cornwall was undertaken during 2006–2011, in which chicks were removed from the nest in Devon, hand-reared and then delayed-released. The survival of the birds to four time points in the year after release was analysed in relation to the effect of rearing factors, using a multivariable logistic regression model. Individuals with higher body weight at capture were more likely to survive to 1 January and 1 May in the year following release, and individuals released in June and July were more likely to survive than those released in August. Individuals released in 2006 and 2011 had a higher survival rate than those released during 2007–2010. Timing of capture, time spent at each stage in captivity, medication and the detection of parasites in the brood had no significant effect. Immunosuppressive disease, weather factors and predator activity may have led to some of the observed differences in survival. This analysis provides evidence with which to plan future translocation projects for cirl buntings and other passerine birds

    Composition and energy spectra of cosmic ray nuclei above 500 GeV/nucleon from the JACEE emulsion chambers

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    The composition and energy spectra of charge groups (C - 0), (Ne - S), and (Z approximately 17) above 500 GeV/nucleon from the experiments of JACEE series balloonborne emulsion chambers are reported. Studies of cosmic ray elemental composition at higher energies provide information on propagation through interstellar space, acceleration mechanisms, and their sources. One of the present interests is the elemental composition at energies above 100 GeV/nucleon. Statistically sufficient data in this energy region can be decisive in judgment of propagation models from the ratios of SECONDARY/PRIMARY and source spectra (acceleration mechanism), as well as speculative contributions of different sources from the ratios of PRIMARY/PRIMARY. At much higher energies, i.e., around 10 to the 15th power eV, data from direct observation will give hints on the knee problem, as to whether they favor an escape effect possibly governed by magnetic rigidity above 10 to the 16th power eV

    Characteristics of central collision events in Fe-nucleus interactions for 20 - 60 GeV/nucleon

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    A counter emulsion hybrid chamber in Japanese-American Cooperative Emulsion Experiment (JACEE-3) was flown on a balloon at the altitude (5.4 g/sq cm) in 1982 with the objective of probing the heavy nuclear collisions above 20 GeV per nucleon. In the energy region, it is suggested that nucleus-nucleus collisions provide dense collisions complex through compression and secondary particle production. In the lower energy region, an evidence of collective flow has been reported. And also, at higher energy region, it has been argued that nucleus has rather large stopping power. In this paper, the high multiplicity characteristics of Fe nucleus central collisions with energies 20 to 50 GeV/nucleon are presented. This is considered to be relevant to compressibility and collective flow of nuclear matter

    Primary cosmic ray spectra in the range 20-60 GeV/n

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    Energy spectra for primary cosmic rays C-Fe above 20 GeV/n were measured on a balloon flight from Greenville S.C. in June 1982 with a hybrid electronic counter-emulsion chamber experiment. Fluxes above the atmosphere appear in general agreement with previously published values. The heavy events included in this data will be used along with the JACEE passive chamber data to provide a heavy composition direct measurement from 10 to the 12th power to approximately 10 to the 15th power eV total energy

    The response of a scintillation counter below an emulsion chamber to heavy nucleus interactions in the chamber

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    In 1982 a hybrid electronic counter-emulsion chamber experiment was flown on a balloon to study heavy nucleus interactions in the 20 to approximately 100 GeV/AMU energy range. A gas Cerenkov counter, two solid Cerenkov counters, and a proportional counter hodoscope gave the primary energy, the primary charge and the trajectory of the particles, respectively. Using the trajectory information cosmic ray nuclei of Z 10 were found reliably and efficiently, and interaction characteristics of the Fe group nuclei were measured in the chamber. A plastic scintillator below the emulsion chamber responded to showers resulting from interactions in the chamber and to noninteracting nuclei. Data on the response of the counter have been compared with simulations of hadronic-electromagnetic cascades to derive the average neutral energy fraction released by the heavy interactions, and to predict the performance of this kind of counter at higher energies. For the interacting events of highest produced particles multiplicity comparison between various simulations and the shower counter signal have been made

    Low molecular weight heparin downregulates tissue factor expression and activity by modulating growth factor receptor-mediated induction of nuclear factor-ÎșB

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    Treatment of cancer patients with low molecular weight heparin (LMWH) appears to have beneficial effects. In this study, the influence of low molecular weight heparin (LMWH) on tissue factor (TF) expression and activity in five cell lines from various tissues was analysed and explored. Incubation of cells with LMWH (0-2000μg/ml) resulted in the downregulation of TF mRNA expression which was both LMWH concentration-dependent and time-dependent. Downregulation of TF was also measured as decreased cellular TF antigen and activity. Consistently, incubation of cells with LMWH suppressed the nuclear localisation and the transcriptional activity of NFÎșB. Decreased TF mRNA was largely achievable by incubating the cells with an NFÎșB inhibitor alone whilst incubation with betulinic acid to activate NFÎșB reversed the inhibitory influence of LMWH. Cells were also incubated with a range of concentrations of EGF (0-10ng/ml), bFGF (0-20ng/ml) or VEGF (0-4ng/ml) in the presence or absence of LMWH (200μg/ml) for 24h and TF antigen measured. Inclusion of LMWH reduced TF expression in response to EGF, bFGF or VEGF but TF expression was partially restored by increasing concentrations of the growth factors. We conclude that LMWH downregulates TF expression in vitro through a mechanism that involves interference with the function of growth factors which in turn is mediated through the downregulation of the transcriptional activity of NFÎșB. This mechanism may also explain some of the beneficial influences attributed to LMWH therapy in the treatment of cancer patients

    New calculations and measurements of the Coulomb cross-section for the production of direct electron pairs by high energy nuclei

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    Recently, new calculations were made of the direct Coulomb pair cross section that rely less in arbitrary parameters. More accurate calculations of the cross section down to low pair energies were made. New measurements of the total direct electron pair yield, and the energy and angular distribution of the electron pairs in emulsion were made for O-16 at 60 and 200 GeV/amu at S-32 at 200 GeV/amu which give satisfactory agreement with the new calculations. These calculations and measurements are presented along with previous accelerator measurements made of this effect during the last 40 years. The microscope scanning criteria used to identify the direct electron pairs is described. Prospects for application of the pair method to cosmic ray energy measurements in the region 10 (exp 13) to 10 (exp 15) eV/amu are discussed
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