Antiseptics: from the past to the presence

This article is dedicated to historical aspect of the use of antiseptics, and it contains data from the modern scientific literature about the interactions between antiseptics and pathogens in biofilms.В статье рассмотрен исторический аспект применения антисептиков, а также приведены данные из современной научной литературы о взаимодействии антисептиков и патогенов в составе биопленок

Escherichia coli: the role of development of surgical pathology and resistance at the modern stage

This article presents the trends in the participation of Escherichia coli in the formation of the microbial landscape of surgical pathology at the modern stage, as well as some features of its resistance to antimicrobial agents.В данной статье рассмотрены тенденции участия кишечной палочки в формировании микробного пейзажа хирургической патологии на современном этапе, а также некоторые особенности ее резистентности к антимикробным препаратам

Modern Conceptions about the Mechanisms of Interaction Between Biofilm and Cellular Immunity Factors

Features of the cellular immune response in the presence of a microbial biofilm are well described in the literature. Based on numerous studies, it became possible to establish a number of patterns: mature biofilms are better protected from immune factors, the effectiveness of antibiofilm strategies depends on species of the microorganisms, forming the biofilm, and, accordingly, on the composition of the biopolymer matrix. For example, rhamnolipids and alginate of Pseudomonas aeruginosa exert a significant negative effect on the function of immunocompetent cells. The bacteria of biofilms became able to turn to their advantage many of the protective reactions developed by the immune system and fixed evolutionarily, applying them for the growth and development of the microbial consortium

CONTENTS OF LYMPHOCYTE SUB-POPULATIONS IN THE CHILDREN WITH ACUTE LEUKEMIA AND LYMPHOMAS DEPENDENT ON INFECTIOUS COMPLICATION AND NEUTROPENIA

Abstract. The aim of the present work was to evaluate the contents of some lymphocyte sub-populations in peripheral blood of the children with tumors of hematopoietic and lymphoid tissues, depending on infectious complication of cytostatic therapy and neutropenia. In all children undergoing cytostatic therapy for acute lympho-blastic leukemia and non-B cell non-Hodgkinґs lymphomas, we found significant decrease in the numbers of CD95 lymphocytes, absolute amounts of natural killer cells (CD16, CD56-lymphocytes) and activated lymphocytes (СD11b, HLA-DR-cells), irrespective of neutrophile numbers in their blood and infectious complications. However, absolute number of CD25- lymphocytes was significantly decreased in the children with neutropenia. Relative contents of CD16, CD56, СD11b, HLA-DR, CD25-lymphocytes did not significantly differ from those in healthy children, or they were found to be significantly increased

FEATURES OF CD34+ CELL KINETICS IN CHILDREN WITH DIFFERENT KINDS OF INFLAMMATION

Characteristics of CD34+ cells mobilization were studied in children suffering with various diseases, like as their dependence on type and extent of inflammatory response. It was revealed that the children with signs of systemic inflammatory response syndrome exhibit a significant increase of absolute content and percentage of circulating CD34+ cells, whereas children with frequent infections, and with clinical signs of allergy during recurrence of their chronic allergic disease showed a significant decrease in CD34+ cell percentage. Meanwhile, children with allergoses, and those with common recurrent infectious states did not reveal any deviations in CD34+ cells from normal values

Оценка мнения студентов о дистанционном образовании: преимущества и недостатки нового формата обучения

This article addresses the issue of transition to distance learning, including those caused by introduction of a high-alert regime related to spreading a new coronavirus infection. As a result, modern society faced a new, equally important task aimed to develop a convenient educational system that provides high-quality education in the changing conditions of modern reality. Academic institutions nowadays study innovation most intensively and develop strategies to help educators becoming more efficient and technically save. Leaving the traditional form of teaching has opened up the possibility of a more flexible and dynamic learning process. The authors consider positive and negative aspects of this form of organizing educational activities by both students and teaching staff, list the difficulties faced by students and teachers in the training process. The system of distance education in our country is not perfect yet. The technology of organizing the assessment of the distance learning quality allows identifying shortcomings and their causes in the system. Therefore, the paper presents the results of the 1st year student questionnaires at the Dental Faculty of South-Ural State Medical University of the Ministry of Healthcare of the Russian Federation. Its purpose was to assess the satisfaction of students with the quality of organization, the distance learning content, as well as outline ways of further development and prospects for using remote educational technologies at a medical university. Remote educational technologies are a modern and popular way to implement educational programs, which on one hand allows students to choose a convenient time mode for learning material. However, the survey results show that the quality of distance learning is lower compared to traditional full-time education.В данной статье раскрывается понятие дистанционного обучения в современном мире. Рассматриваются положительные и отрицательные стороны данного способа получения знаний, а также  упоминаются сложности, с которыми сталкиваются обучающиеся и преподаватели в процессе обучения. Делается вывод, что дистанционное образование в нашей стране еще недостаточно развито и требует решений имеющихся проблем