127 research outputs found
Energy of eigen-modes in magnetohydrodynamic flows of ideal fluids
Analytical expression for energy of eigen-modes in magnetohydrodynamic flows
of ideal fluids is obtained. It is shown that the energy of unstable modes is
zero, while the energy of stable oscillatory modes (waves) can assume both
positive and negative values. Negative energy waves always correspond to
non-symmetric eigen-modes -- modes that have a component of wave-vector along
the equilibrium velocity. These results suggest that all non-symmetric
instabilities in ideal MHD systems with flows are associated with coupling of
positive and negative energy waves. As an example the energy of eigen-modes is
calculated for incompressible conducting fluid rotating in axial magnetic
field.Comment: 10 pages, 3 figure
Generation and Structure of Solitary Rossby Vortices in Rotating Fluids
The formation of zonal flows and vortices in the generalized
Charney-Hasegawa-Mima equation is studied. We focus on the regime when the size
of structures is comparable to or larger than the deformation (Rossby) radius.
Numerical simulations show the formation of anticyclonic vortices in unstable
shear flows and ring-like vortices with quiescent cores and vorticity
concentrated in a ring. Physical mechanisms that lead to these phenomena and
their relevance to turbulence in planetary atmospheres are discussed.Comment: 3 pages in REVTeX, 5 postscript figures separately, submitted to
Phys. Rev.
Polymeric human Fc-fusion proteins with modified effector functions
The success of Fc-fusion bio-therapeutics has spurred the development of other Fc-fusion products for treating and/or vaccinating against a range of diseases. We describe a method to modulate their function by converting them into well-defined stable polymers. This strategy resulted in cylindrical hexameric structures revealed by tapping mode atomic force microscopy (AFM). Polymeric Fc-fusions were significantly less immunogenic than their dimeric or monomeric counterparts, a result partly owing to their reduced ability to interact with critical Fc-receptors. However, in the absence of the fusion partner, polymeric IgG1-Fc molecules were capable of binding selectively to FcÎłRs, with significantly increased affinity owing to their increased valency, suggesting that these reagents may prove of immediate utility in the development of well-defined replacements for intravenous immunoglobulin (IVIG) therapy. Overall, these findings establish an effective IgG Fc-fusion based polymeric platform with which the therapeutic and vaccination applications of Fc-fusion immune-complexes can now be explored
Velocity field in the spiral-wave pattern observed in rotating shallow-water experiments
Experimental and computational study of the passage of an electron beam through the curvilinear element of the Drakon stellarator system in a tenuous plasma
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