The Nambu-Jona-Lasinio model with staggered fermions

We investigate the neighbourhood of the chiral phase transition in a lattice Nambu--Jona-Lasinio model, using both Monte Carlo methods and lattice Schwinger-Dyson equations.Comment: Talks at LAT93, Dallas, U.S.A. Postscript file, 6 pages, figures include

Decorrelation of the topological charge in tempered Hybrid Monte Carlo simulations of QCD

We study the improvement of simulations of QCD with dynamical Wilson fermions by combining the Hybrid Monte Carlo algorithm with parallel tempering. As an indicator for decorrelation we use the topological charge.Comment: LATTICE99 (algorithms and machines

Resolution of the Landau pole problem in QED

We present new numerical results for the renormalized mass and coupling in non-compact lattice QED with staggered fermions. Implications for the continuum limit and the role of the Landau pole are discussed.Comment: 3 pages, talk presented by H. St\"uben at Lattice '97, Edinburg

Meson decay constants from Nf=2 clover fermions

We present recent results for meson decay constants calculated on configurations with two flavours of O(a)-improved Wilson fermions. Non-perturbative renormalisation is applied and quark mass dependencies as well as finite volume and discretisation effects are investigated. In this work we also present a computation of the coupling of the light vector mesons to the tensor current using dynamical fermions.Comment: 6 pages, contribution to Lattice2005(Hadron spectrum and quark masses

A determination of the strange quark mass for unquenched clover fermions using the AWI

Using the O(a) Symanzik improved action an estimate is given for the strange quark mass for unquenched (nf=2) QCD. The determination is via the axial Ward identity (AWI) and includes a non-perturbative evaluation of the renormalisation constant. Numerical results have been obtained at several lattice spacings, enabling the continuum limit to be taken. Results indicate a value for the strange quark mass (in the MSbar-scheme at a scale of 2GeV) in the range 100 - 130MeV.Comment: 6 pages, contribution to Lattice2005(Hadron spectrum and quark masses), uses PoS.cl

The present status of non-compact lattice QED

We give a 1993 update of non-compact lattice QED, in particular the chiral condensate, finite size effects and meson mass ratios. We compare descriptions of the phase transition. Our previous conclusions remain valid.Comment: Poster presentation at LAT93, Dallas, U.S.A. Postscript file, 4 pages, figures included. Preprint numbers DESY-93-178, FUB-HEP/93-20 and HLRZ 93-7

A Determination of the Lambda Parameter from Full Lattice QCD

We present a determination of the QCD parameter Lambda in the quenched approximation (n_f=0) and for two flavours (n_f=2) of light dynamical quarks. The calculations are performed on the lattice using O(a) improved Wilson fermions and include taking the continuum limit. We find Lambda_{n_f=0} = 259(1)(20) MeV and Lambda_{n_f=2} = 261(17)(26) MeV}, using r_0 = 0.467 fm to set the scale. Extrapolating our results to five flavours, we obtain for the running coupling constant at the mass of the Z boson alpha_s(m_Z) = 0.112(1)(2). All numbers refer to the MSbar scheme.Comment: 25 pages, 9 figure

Targeting of Rad51-dependent homologous recombination: implications for the radiation sensitivity of human lung cancer cell lines

The aim of the present work was to study the role of Rad51-dependent homologous recombination in the radiation response of non-small-cell lung cancer (NSCLC) cell lines. A dose- and time-dependent increase in the formation of Rad51 and γ-H2AX foci with a maximum at about 4 and 1 h after irradiation, followed by a decrease, has been found. The relative fraction of cells with persisting Rad51 foci was 20–30% in radioresistant and 60–80% in radiosensitive cell lines. In comparison, a higher fraction of residual Dsb was evident in cell lines with nonfunctional p53. Transfection with As-Rad51 significantly downregulates radiation-induced formation of Rad51 foci and increases apoptosis, but did not influence the rejoining of DNA double-strand breaks. Interestingly, wortmannin, a well-known inhibitor of nonhomologous end-joining, also inhibits Rad51 foci formation. In general, there was no correlation between the clonogenic survival at 2 Gy and the percentage of initial Rad51 or γ-H2AX foci after ionising radiation (IR). The most reliable predictive factor for radiosensitivity of NSCLC cell lines was the relative fraction of Rad51 foci remaining at 24 h after IR. Although most of the Rad51 foci are co-localised with γ-H2AX foci, no correlation of the relative fraction of persisting γ-H2AX foci and SF2 is evident