The Globular Cluster System in the Inner Region of M87

1057 globular cluster candidates have been identified in a WFPC2 image of the inner region of M87. The Globular Cluster Luminosity Function (GCLF) can be well fit by a Gaussian profile with a mean value of m_V^0=23.67 +/- 0.07 mag and sigma=1.39 +/- 0.06 mag (compared to m_V^0=23.74 mag and sigma=1.44 mag from an earlier study using the same data by Whitmore it et al. 1995). The GCLF in five radial bins is found to be statistically the same at all points, showing no clear evidence of dynamical destruction processes based on the luminosity function (LF), in contradiction to the claim by Gnedin (1997). Similarly, there is no obvious correlation between the half light radius of the clusters and the galactocentric distance. The core radius of the globular cluster density distribution is R_c=56'', considerably larger than the core of the stellar component (R_c=6.8''). The mean color of the cluster candidates is V-I=1.09 mag which corresponds to an average metallicity of Fe/H = -0.74 dex. The color distribution is bimodal everywhere, with a blue peak at V-I=0.95 mag and a red peak at V-I=1.20 mag. The red population is only 0.1 magnitude bluer than the underlying galaxy, indicating that these clusters formed late in the metal enrichment history of the galaxy and were possibly created in a burst of star/cluster formation 3-6 Gyr after the blue population. We also find that both the red and the blue cluster distributions have a more elliptical shape (Hubble type E3.5) than the nearly spherical galaxy. The average half light radius of the clusters is ~2.5 pc which is comparable to the 3 pc average effective radius of the Milky Way clusters, though the red candidates are ~20% smaller than the blue ones.Comment: 40 pages, 17 figures, 4 tables, latex, accepted for publication in the Ap

Onset of Phase Synchronization in Neurons Conneted via Chemical Synapses

We study the onset of synchronous states in realistic chaotic neurons coupled by mutually inhibitory chemical synapses. For the realistic parameters, namely the synaptic strength and the intrinsic current, this synapse introduces non-coherences in the neuronal dynamics, yet allowing for chaotic phase synchronization in a large range of parameters. As we increase the synaptic strength, the neurons undergo to a periodic state, and no chaotic complete synchronization is found.Comment: to appear in Int. J. Bif. Chao

Robustness and Enhancement of Neural Synchronization by Activity-Dependent Coupling

We study the synchronization of two model neurons coupled through a synapse having an activity-dependent strength. Our synapse follows the rules of Spike-Timing Dependent Plasticity (STDP). We show that this plasticity of the coupling between neurons produces enlarged frequency locking zones and results in synchronization that is more rapid and much more robust against noise than classical synchronization arising from connections with constant strength. We also present a simple discrete map model that demonstrates the generality of the phenomenon.Comment: 4 pages, accepted for publication in PR

Towards a Full Census of the Obscure(d) Vela Supercluster using MeerKAT

Recent spectroscopic observations of a few thousand partially obscured galaxies in the Vela constellation revealed a massive overdensity on supercluster scales straddling the Galactic Equator (l $\sim$ 272.5deg) at $cz \sim 18000$km/s. It remained unrecognised because it is located just beyond the boundaries and volumes of systematic whole-sky redshift and peculiar velocity surveys - and is obscured by the Milky Way. The structure lies close to the apex where residual bulkflows suggest considerable mass excess. The uncovered Vela Supercluster (VSCL) conforms of a confluence of merging walls, but its core remains uncharted. At the thickest foreground dust column densities (|b| < 6 deg) galaxies are not visible and optical spectroscopy is not effective. This precludes a reliable estimate of the mass of VSCL, hence its effect on the cosmic flow field and the peculiar velocity of the Local Group. Only systematic HI-surveys can bridge that gap. We have run simulations and will present early-science observing scenarios with MeerKAT 32 (M32) to complete the census of this dynamically and cosmologically relevant supercluster. M32 has been put forward because this pilot project will also serve as precursor project for HI MeerKAT Large Survey Projects, like Fornax and Laduma. Our calculations have shown that a survey area of the fully obscured part of the supercluster, where the two walls cross and the potential core of the supercluster resides, can be achieved on reasonable time-scales (200 hrs) with M32.Comment: 10 pages, 3 figures, accepted for publication, Proceedings of Science, workshop on "MeerKAT Science: On the Pathway to the SKA", held in Stellenbosch 25-27 May 201

Ground-state proton decay of 69Br and implications for the rp-process 68Se waiting-point

The first direct measurement of the proton separation energy, Sp, for the proton-unbound nucleus 69Br is reported. Of interest is the exponential dependence of the 2p-capture rate on Sp which can bypass the 68Se waiting-point in the astrophysical rp process. An analysis of the observed proton decay spectrum is given in terms of the 69Se mirror nucleus and the influence of Sp is explored within the context of a single-zone X-ray burst model.Comment: 6 pages, 6 figures, INPC 2010 conference proceeding

Unfolding cross-linkers as rheology regulators in F-actin networks

We report on the nonlinear mechanical properties of a statistically homogeneous, isotropic semiflexible network cross-linked by polymers containing numerous small unfolding domains, such as the ubiquitous F-actin cross-linker Filamin. We show that the inclusion of such proteins has a dramatic effect on the large strain behavior of the network. Beyond a strain threshold, which depends on network density, the unfolding of protein domains leads to bulk shear softening. Past this critical strain, the network spontaneously organizes itself so that an appreciable fraction of the Filamin cross-linkers are at the threshold of domain unfolding. We discuss via a simple mean-field model the cause of this network organization and suggest that it may be the source of power-law relaxation observed in in vitro and in intracellular microrheology experiments. We present data which fully justifies our model for a simplified network architecture.Comment: 11 pages, 4 figures. to appear in Physical Review

The Spin of M87 as measured from the Rotation of its Globular Clusters

We revisit the kinematical data for 204 globular clusters in the halo of M87. Beyond 3 r_eff along the major axis of the galaxy light, these globular clusters exhibit substantial rotation (~ 300 +/- 70 km/s) that translates into an equally substantial spin (lambda ~ 0.18). The present appearance of M87 is most likely the product of a single major merger, since this event is best able to account for so sizable a spin. A rotation this large makes improbable any significant accretion of material after this merger, since that would have diluted the rotation signature. We see weak evidence for a difference between the kinematics of the metal-poor and metal-rich population, in the sense that the metal-poor globular clusters appear to dominate the rotation. If, as we suspect, the last major merger event of M87 was mainly dissipationless and did not trigger the formation of a large number of globular clusters, the kinematic difference between the two could reflect their orbital properties in the progenitor galaxies; these differences would be compatible with these progenitors having formed in dissipational mergers. However, to put strong kinematic constraints on the origin of the globular clusters themselves is difficult, given the complex history of the galaxy and its last dominant merger event.Comment: 20 pages (AAS two column style, including 1 table and 7 figures) accepted in the AJ (November issue), also available at http://www.ucolick.org/~mkissler

Mitochondrial Abnormality Associates with Type-Specific Neuronal Loss and Cell Morphology Changes in the Pedunculopontine Nucleus in Parkinson Disease

Cholinergic neuronal loss in the pedunculopontine nucleus (PPN) associates with abnormal functions, including certain motor and nonmotor symptoms. This realization has led to low-frequency stimulation of the PPN for treating patients with Parkinson disease (PD) who are refractory to other treatment modalities. However, the molecular mechanisms underlying PPN neuronal loss and the therapeutic substrate for the clinical benefits following PPN stimulation remain poorly characterized, hampering progress toward designing more efficient therapies aimed at restoring the PPN's normal functions during progressive parkinsonism. Here, we investigated postmortem pathological changes in the PPN of PD cases. Our study detected a loss of neurons producing gamma-aminobutyric acid (GABA) as their output and glycinergic neurons, along with the pronounced loss of cholinergic neurons. These losses were accompanied by altered somatic cell size that affected the remaining neurons of all neuronal subtypes studied here. Because studies showed that mitochondrial dysfunction exists in sporadic PD and in PD animal models, we investigated whether altered mitochondrial composition exists in the PPN. A significant up-regulation of several mitochondrial proteins was seen in GABAergic and glycinergic neurons; however, cholinergic neurons indicated down-regulation of the same proteins. Our findings suggest an imbalance in the activity of key neuronal subgroups of the PPN in PD, potentially because of abnormal inhibitory activity and altered cholinergic outflow