88 research outputs found

    On the Change in Archivability of Websites Over Time

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    As web technologies evolve, web archivists work to keep up so that our digital history is preserved. Recent advances in web technologies have introduced client-side executed scripts that load data without a referential identifier or that require user interaction (e.g., content loading when the page has scrolled). These advances have made automating methods for capturing web pages more difficult. Because of the evolving schemes of publishing web pages along with the progressive capability of web preservation tools, the archivability of pages on the web has varied over time. In this paper we show that the archivability of a web page can be deduced from the type of page being archived, which aligns with that page's accessibility in respect to dynamic content. We show concrete examples of when these technologies were introduced by referencing mementos of pages that have persisted through a long evolution of available technologies. Identifying these reasons for the inability of these web pages to be archived in the past in respect to accessibility serves as a guide for ensuring that content that has longevity is published using good practice methods that make it available for preservation.Comment: 12 pages, 8 figures, Theory and Practice of Digital Libraries (TPDL) 2013, Valletta, Malt

    Influence of anatomy of cervical ostium on the efficiency of cervical traversing after relaxation protocol in Santa Ines ewes.

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    Abstract: Ewes have certain particularities in the cervical anatomy leading to the commercial use of surgical methods for collecting embryos in this species. However, the literature shows that Non-Surgical Embryo Recovery (NSER) is possible through specific protocols for cervical relaxation (Fonseca et al., 2019. Reprod Fertil Devel, 31:17-26). The cervical ostium may have several classifications: flap, duckbill, rosette, rose, spiral or papilla. This study aimed to assess the influence of cervical ostium anatomy on the difficulty of traversing cervical rings. In conclusion, the current data suggest that the morphology of cervical ostium may have influence on the success of embryo collection by Non-Surgical Embryo Recovery (NSER) technique. [Influência da anatomia do óstio cervical na eficiência da transposição cervical após protocolo de relaxamento em ovelhas Santa Inês].Edição dos resumos do XXIII Congresso Brasileiro de Reprodução Animal, Gramado, RS, Brasil, 15 a 17 de maio 2019

    Superovulation of Morada Nova Ewes with protocols diverging only progestagem duration regimen.

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    Abstract: Despite the importance of Morada Nova for Northeast sheep production systems, information about embryo production of this breed is scarce with only one report of multiple ovulation and surgical embryo recovery (Brasil et al., 2016. ArqBrasMedVetZootec, 68:1390-1394) and non-surgical uterine access (Fonseca et al., 2016. Theriogenology, 86:144-151). In this context, the objective of this study was to evaluate the efficiency of different superovulation protocols in pluriparous Morada Nova using nonsurgical embryo recovery (NSER) to access embryo production. [Superovulação de ovelhas Morada Nova com protocolos divergentes apenas do regime de duração da progestágeno].Edição dos resumos do XXIII Congresso Brasileiro de Reprodução Animal, Gramado, RS, Brasil, 15 a 17 de maio 2019

    Donor evaluation and scoring for non-surgical embryo transfer in Santa Inês sheep.

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    Abstract: This study checked the effectiveness of ranking the difficulty to clip/traction and traverse the cervix with the Hegar dilator as a predictor method for selecting suitable animals to undergo NSER. A total of 46 pluriparous Santa Inês received intravaginal sponges containing 60 mg medroxyprogesterone (Progespon®, Syntex, Buenos Aires, Argentina) during six days plus 200 IU eCG (Novormon 5000®, Syntex, Buenos Aires, Argentina) i.m. and 37.5 ?g d-cloprostenol (Prolise®, ARSA S.R.L., Buenos Aires, Argentina) latero-vulvar 24 h before sponge removal. This grading system may indicate the probability of individual animals to successfully proceed with NSER. It is suggested that a selective system for donors should include an attempt to clip/traction/traverse the cervix, ranking the difficulty of the process, before starting a MOET/NSER protocol. Animals that receive scores 4 and 5 could be excluded from the protocol in order to prevent the use of unable or laborious animals, avoiding wasting resources. [Avaliação e ranqueamento de doadoras para coleta de embriões não cirúrgica em ovelhas Santa Inês].Edição dos resumos do XXIII Congresso Brasileiro de Reprodução Animal, Gramado, RS, Brasil, 15 a 17 de maio 2019

    Induction of synchronous estrus in Morada Nova ewes: effects of distinct progestagen duration regimen and non-surgical embryo recovery as a tool to access efficiency measurements.

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    Abstract: The first stet for applying superovulation is to know the responsiveness of the ewe to different estrous synchronous protocol duration and possible implications on embryo yield. On the other hand for nonsurgical embryo recovery (NSER) a well consolidated protocol should be tested and, in Morada Nova ewes, successful non-surgical uterine access was reported (Fonseca et al., 2019. Reprod Fertil Devel, 31:17-26). In this context, the objective of this study was to evaluate the efficiency different synchronous estrus induction and NSER as additional tool to evaluate the results these protocols in pluriparous Morada Nova ewes. A total of 18 pluriparous sheep were divided into three treatment groups with 6 (T6, n=6), 9 (T9, n=6) and 12 (T12, n=6) days of 60 mg of medroxyprogesterone acetate (Progespon®, Zoetis, Campinas, São Paulo, Brazil). The NSER mean duration was 27.6±1.4 min, with recovery of 99.8% of injected fluid and embryo recovery rate of 62.97% (17/27). These preliminary results indicated that all protocols provided similar results and that NSER can be successfully performed and used as additional toll in synchronous estrous induced Morada Nova ewes independently from the duration of progestogen regimen to assure that viable embryos can be produced by ewes subjected by these protocols. [Indução do estro sincrônico em ovelhas Morada Nova: efeitos do regime de duração distinto do progestágeno e recuperação não cirúrgica do embrião como uma ferramenta para acessar medidas de eficiência].Edição dos resumos do XXIII Congresso Brasileiro de Reprodução Animal, Gramado, RS, Brasil, 15 a 17 de maio 2019

    Implementation and effects of user participation in playground management: a comparative study of two Swedish municipalities

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    This paper describes and analyses how customer orientation strategies, with the focus on user participation, are implemented in playground management and their effects on managers’ attitudes and work with physical playgrounds. A comparative case study was conducted in two Swedish municipalities that involve users in different ways: through a manager-driven participation process and through informal user-initiated dialogue. The empirical material consisted of qualitative interviews with professionals in the management organisations and studies of local playgrounds. Implementation of strategies for user participation and tactical management activities appeared to be of importance. The manager-driven participation strategy was associated with a particularly positive attitude among managers, but also difficulties such as maintaining continuous dialogue with users. The small differences found in playground provision between the two municipalities give reason to question the physical effects of participation processes, and show the need for further research

    Second step for non-surgical embryo transfer in sheep: Cervical transposing in diestrus nulliparous and pluriparous ewes.

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    Abstract: Transcervical transposition in sheep cannot be achieved without any cervical relaxation drug (Gusmão et al., 2007, RevBrasSaúdeProdAn, 8:1-10). The first step testing the viability of cervical relaxation protocol for transcervical embryo transfer in sheep is to check the effect of these drugs on pregnancy. Although combination of estradiol benzoate and oxytocin did not compromise pregnancy establishment, no attempts of cervical transposition was reported in sheep (Lewis, 2010. SheepGoatResJ, 25:21-25). In Brazilian conditions, preliminary study showed that association of hCG with E2-OT association given at expected times for embryo transfer appeared not disturbing pregnancy (Arrais et al., 2018. AnimRep, 15:338), but cervical transposition was not tested. [Segundo passo para a transferência não cirúrgica de embriões em ovelhas: Transposição cervical em ovelhas nuliparas e pluríparas em diestro].Edição dos resumos do XXIII Congresso Brasileiro de Reprodução Animal, Gramado, RS, Brasil, 15 a 17 de maio 2019

    Cervical mucus is not efficient to predict the ovulation time in of Santa Ines ewes synchronized to estrus.

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    Abstract: In goats, it has been demonstrated that cervical mucus evaluation is able to predict the time of ovulation after estrous hormonal synchronization, which is efficient in determining the ideal time of Artificial Insemination (Fonseca et al., 2017. Reprod Biol; 17:363-369). However, in sheep, this parameter is not established in the literature. The study was conducted in Coronel Pacheco (latitude 21?33 'S and longitude 43?16' W), MG, Brazil. These data are different from that reported in goats, i.e., the standardization of mucus score 3 or 4 at the time of ovulation. It may be concluded that the use of cervical mucus is alone not an efficient parameter to detect the time of ovulation in sheep. [O muco cervical não é eficiente em predizer o momento da ovulação em ovelhas Santa Inês sincronizadas ao estro].Edição dos resumos do XXIII Congresso Brasileiro de Reprodução Animal, Gramado, RS, Brasil, 15 a 17 de maio 2019

    A controlled study of supplementation with essential amino acids and α-keto acids in the conservative management of patients with chronic renal failure

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    Art und Zusammensetzung einer optimalen eiweißarmen Ernährung für Patienten mit Niereninsuffizienz sind weiterhin umstritten. Die orale medikamentöse Behandlung mit essentiellen Aminosäuren oder α-Ketosäuren wird häufig empfohlen. Unsere Untersuchungen vergleichen nacheinander bei 15 ambulanten Patienten mit chronischem Nierenversagen (mittlere Kreatinin-Clearance 10,8 ml/min) unter einer eiweißarmen Ernährung von 0,57 g/kg Körpergewicht (40 g/70 kg) die Wirkung einer Substitution mit essentiellen Aminosäuren, danach die Substitution mit α-Ketosäuren gegenüber Plazebo. Der nachgewiesene Proteingehalt in der Nahrung betrug 0,55 g/kg, die Energiezufuhr 27 kcal/kg Körpergewicht, wie mehrfach Ernährungsprotokolle über jeweils 7 Tage bei den Patienten zeigen ließen. Nach einer Vorperiode von 6 Wochen nur unter diätetischen Maßnahmen erhielten alle Patienten zusätzlich 0,112 g essentielle Aminosäuren/kg Körpergewicht über 6 Wochen, danach in einer Doppelblinduntersuchung 0,105 g α-Ketosäuren/kg Körpergewicht im Vergleich gegenüber Plazebo, ebenfalls jeweils über 6 Wochen. Nüchtern-Blutuntersuchungen wurden für ein Standard-Laborwertprogramm, insbesondere für 15 Proteinmangelparameter, alle 3 Wochen durchgeführt, ferner anthropometrische und klinische Kontrollen. Die Laborwerte erbrachten keine Hinweise auf einen manifesten Proteinmangel. Die Therapie mit α-Ketosäuren erniedrigte die Phosphatspiegel signifikant (p<0,05). Dagegen konnten weder unter essentiellen Aminosäuren oder α-Ketosäuren andere für den Patienten wesentliche Effekte nachgewiesen werden. Deshalb erscheint uns eine Substitution mit essentiellen Aminosäuren oder Ketosäuren überflüssig bei Patienten mit einer chronischen Niereninsuffizienz, die sich in einem stabilen Stoffwechselgleichgewicht befinden und mit einer Eiweißzufuhr von 0,55 g/kg Körpergewicht behandelt werden. Oral therapy with essential amino acids (EAA) or α-keto acids (α-KA) has been recommended in patients with renal failure, but quality and quantity of optimal protein intake are still controversial. This study compares sequentially the effect of supplementation with EAA, and with α-KA versus placebo in 15 ambulatory patients with chronic renal failure (average creatinine clearance 10.8 ml/min), maintained on a protein diet of 0.57 g/kg body weight (40 g for a 70-kg patient). The actual dietary intake averaged 0.55 g protein/kg and 27 kcal/kg according to repeated 7-day dietary recordings. After a 6-week baseline period on this diet, all patients received additionally 0.112 g EAA/kg for 6 weeks followed by a double-blind cross-over study of 0.105 g α-KA/kg versus placebo supplementation for 6 weeks each. Fasting blood samples for multiple parameters, including 15 indicators for protein deficiency, as well as anthropometric and clinical data were evaluated every 3 weeks. Laboratory data revealed no indications of protein deficiency. Therapy with α-KA diminished serum phosphate concentration (p<0.05), however no other significant beneficial effects could be demonstrated during supplementation with either EAA or α-KA. Therefore, such supplementation to a 0.55-g/kg-protein diet appears superfluous in stable ambulatory patients with renal insufficiency.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/41743/1/394_2005_Article_BF02020747.pd
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