Cytogenetic Studies of Normal and Cleft-Palate Epitheliums in Mice

This study investigated teratogenic activity on a cellular level through analysis of the cytogenetic complex in cleft-palate epithelial cells from the progenies of mice treated with cortisone. Analysis showed no detectable aberration from a normal chromosomal complement.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/68120/2/10.1177_00220345690480041601.pd

Effects of Composite Restorations on the Periodontal Membrane in Monkeys

We evaluated the histopathological response of the periodontal membrane to intentionolly-replanted teeth carrying composite (experimental) and silver amalgam (control) restorations in the middle third of each root. The study revealed that the amalgam produced, in the periodontal tissues, an initial localized inflammation that subsided with the subsequent formation of a fibrous capsule. However, the periodontal membrane adjacent to the composite resin restorations demonstrated chronic inflammation. It was concluded that the composite evoked chronic inflammatory responses of the periodontal tissues in monkeys.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/67994/2/10.1177_00220345830620011801.pd

Effects of Amalgam Restorations on the Periodontal Membrane in Monkeys

The response of the periodontal membrane to reimplanted teeth carrying amalgam restorations in the middle third of their roots was studied from seven days to six months after grafting. The study revealed that the amalgam restorations produced an initial localized inflammation in the periodontal tissues that subsided subsequently with the formation of a pseudocapsule.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/66490/2/10.1177_00220345770560092001.pd

Revascularization of the Periodontium After Tooth Grafting in Monkeys

In replanted and homo transplanted teeth a vascular network developed in the blood clot between the two parts of the torn periodontium, which allowed the grafted ligament to regain its vascularity. When dentoalveolar ankylosis developed, the periodontal vasculature was split into a number of vascular clusters. In homotransplants, a definite cellular immunologic response by the host was absent. An acrylic radicular obturator was used.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/67229/2/10.1177_00220345710500025101.pd

The length of the Y chromosome in Nubian males and its location in metaphase spreads

A total of 242 metaphase plates from the peripheral blood of Nubian males living near Aswan, Egypt were studied with respect to the length of the Y chromosome and its location in metaphase spreads. The length of the Y was similar to that found in American Negroes, and the Y chromosome was peripherally located in 79 of the 242 cells.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/47610/1/439_2004_Article_BF00273203.pd

On the peripheral location of the Y chromosome

The location of the Y chromosome in metaphase spreads is studied in groups of (a) 96 normal males, (b) 17 Down's syndrome patients, and (c) 51 patients with Klinefelter's syndrome. The position of the Y is scored as either peripheral or nonperipheral using several of the traditional definitions found in the literature. It is shown that contradictory results may be obtained depending on the particular definition employed and that none of the available definitions capture the essence of the meaning of ‘peripheral’. Therefore a new, standardized definition is introduced—one that applies to both circular and noncircular spreads. Using this new definition, we find definite intergroup variability. The Y is peripheral in normal males, but not in either the Down's or Klinefelter's samples.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/47608/1/439_2004_Article_BF00295405.pd