83 research outputs found

    Estimated proportion of cases averted for different vaccination coverages and at different times to the outbreak in cattle (top panel) and sheep (bottom panel).

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    <p>Estimated proportion of cases averted for different vaccination coverages and at different times to the outbreak in cattle (top panel) and sheep (bottom panel).</p

    Summary flow diagram of the model structure demonstrating the bidirectional RVFV transmission between domestic livestock and the two mosquito species.

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    <p>The structure also shows the infection states of livestock and mosquitoes and the parameters that describe transition pathways. <i>Aedes</i> spp population growth is governed by a fuzzy distribution model that leads to development, through explicitly modelled aquatic stages (Ϫ), of either susceptible or infectious adults. <i>Culex</i> spp population growth is governed by a logistic distribution model that leads to development, through explicitly modelled aquatic stages (Ϫ), of susceptible adults. See vector aquatic stages modelling in the text.</p

    Simulated incidence of RVFV in hosts over 1200 days.

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    <p>The inset graph is a magnification of the full-blown outbreak period.</p

    Estimated proportion of cases averted for different vaccination coverages implemented at the onset of outbreak.

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    <p>The dashed blue line shows the predicted vaccination coverage estimated to reduce the cumulative incidence in each host species by 50% in an outbreak.</p

    Proportional (%) change in cumulative incidence in cattle and sheep upon a ±50% of model parameter values.

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    <p>Proportional (%) change in cumulative incidence in cattle and sheep upon a ±50% of model parameter values.</p

    Predicted temporal relationship between fuzzy (panel A) and logistic probability functions (panel B) and vector: host ratios.

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    <p>Predicted temporal relationship between fuzzy (panel A) and logistic probability functions (panel B) and vector: host ratios.</p

    Impacts of integrating various levels of routine and reactive vaccination required to stop an RVF outbreak using a prefect vaccine (Panel A) and imperfect vaccine with 50% vaccine efficacy (Panel B).

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    <p>Impacts of integrating various levels of routine and reactive vaccination required to stop an RVF outbreak using a prefect vaccine (Panel A) and imperfect vaccine with 50% vaccine efficacy (Panel B).</p

    Expected impacts of biannual (Panel A) and annual (Panel B) periodic vaccination scenarios on the cumulative incidence of RVFV using a perfect vaccine and a vaccine with 50% efficacy.

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    <p>Expected impacts of biannual (Panel A) and annual (Panel B) periodic vaccination scenarios on the cumulative incidence of RVFV using a perfect vaccine and a vaccine with 50% efficacy.</p
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