Effects of Vestibular Rehabilitation Using the Dizziness Handicap Inventory

When individuals have an insult to the vestibular system they often experience symptoms including vertigo, decreased static and dynamic balance, and a decreased ability to participate in activities of daily living. The Dizziness Handicap Inventory (DHI) is a dizzy-specific questionnaire that was developed in 1990 to measure how dizziness and imbalance affect an individual\u27s quality of life. It is an assessment tool, made up of physical, emotional, and functional sub-scales, that has reliability and is easy to administer and score. The purpose of this study was to measure the effectiveness of a vestibular rehabilitation program, using the Dizziness Handicap Inventory, in subjects who had mixed vestibular disorders. Forty-nine randomly selected subjects participated in a telephone survey, using the Dizziness Handicap Inventory, to compare how they felt before and after their vestibular rehabilitation program. Total scores and sub-scores before and after vestibular rehabilitation were calculated and compared, using the sign test, with the alpha level set at .05. Results showed that 57.1 % of the subjects interviewed had significant improvements in their total DHI scores following vestibular rehabilitation. Statistically significant differences in each of the individual sub-scores before and after vestibular rehabilitation was also found to be present (p\u3c.001). Overall, this study demonstrates the benefits that an organized vestibular rehabilitation program can have for patients with mixed vestibular deficits, and how the Dizziness Handicap Inventory can be utilized in the assessment of outcomes

Social Representations of Foreign Aid: Exploring Meaning-Making in Aid Practice in Sulu, Southern Philippines

Conceptualising foreign aid as a controversial social object, this study utilised Social Representations Theory as a social constructionist framework to understand the meanings that arise from people\u27s social interactions in relation to foreign aid practice in a particular historical, political and social context such as the province of Sulu in Southern Philippines. Key informant interviews and group discussions with representatives of various social groups involved in the practice of foreign aid in Sulu were conducted. Research data were examined using thematic analysis. Results showed two interrelated representational systems about foreign aid in the province. First, foreign aid was understood as a valuable resource for peace and development in Sulu. Second, based on narratives of aid practice in the province, the same social object was also represented as a profiteering enterprise that operates at various levels of the aid structure. Results are discussed in terms of meaning-making in aid practice; the possible psychological, social and political consequences of the social meaning of foreign aid as a profiteering enterprise; and the potential of these social representations for reflection, critique and transformation in the practice of foreign aid

Isomorphism of graph classes related to the circular-ones property

We give a linear-time algorithm that checks for isomorphism between two 0-1 matrices that obey the circular-ones property. This algorithm leads to linear-time isomorphism algorithms for related graph classes, including Helly circular-arc graphs, \Gamma-circular-arc graphs, proper circular-arc graphs and convex-round graphs.Comment: 25 pages, 9 figure

CB1 Receptor Antagonism Blocks Stress-Potentiated Reinstatement of Cocaine Seeking in Rats

Rationale Under some conditions, stress, rather than directly triggering cocaine seeking, potentiates reinstatement to other stimuli, including a subthreshold cocaine dose. The mechanisms responsible for stress-potentiated reinstatement are not well defined. Endocannabinoid signaling is increased by stress and regulates synaptic transmission in brain regions implicated in motivated behavior. Objectives The objective of this study was to test the hypothesis that cannabinoid type 1 receptor (CB1R) signaling is required for stress-potentiated reinstatement of cocaine seeking in rats. Methods Following i.v. cocaine self-administration (2 h access/day) and extinction in male rats, footshock stress alone does not reinstate cocaine seeking but reinstatement is observed when footshock is followed by an injection of an otherwise subthreshold dose of cocaine (2.5 mg/kg, i.p.). CB1R involvement was tested by systemic administration of the CB1R antagonist AM251 (0, 1, or 3 mg/kg, i.p.) prior to testing for stress-potentiated reinstatement. Results Stress-potentiated reinstatement was blocked by both 1 and 3 mg/kg AM251. By contrast, AM251 only attenuated food-reinforced lever pressing at the higher dose (i.e., 3 mg/kg) and did not affect locomotor activity at either dose tested. Neither high-dose cocaine-primed reinstatement (10 mg/kg, i.p.) nor footshock stress-triggered reinstatement following long-access cocaine self-administration (6 h access/day) was affected by AM251 pretreatment. Footshock stress increased concentrations of both endocannabinoids, N-arachidonylethanolamine and 2-arachidonoylglycerol, in regions of the prefrontal cortex. Conclusions These findings demonstrate that footshock stress increases prefrontal cortical endocannabinoids and stress-potentiated reinstatement is CB1R-dependent, suggesting that CB1R is a potential therapeutic target for relapse prevention, particularly in individuals whose cocaine use is stress-related

Biogeochemistry of Isotopically-distinct Sources of Lead in a Former WWII Aerial Gunnery Range

Isotopic composition and concentrations of Pb are used to identify sources of anthropogenic and natural Pb and to assess Pb bioavailability in soils and native plants at a former military installation that served as a WWII era aerial gunnery range. Surficial soil and plant samples are obtained both in target practice areas where copious amounts of bullets persist and areas unaffected by target practice that are devoid of bullets. A selective sequential extraction procedure is used to determine the distribution of Pb amongst different soil components: soil carbonates and ion-exchangeable minerals, organics, oxide and hydroxide minerals, and leachate of residual silicate clays. Plants samples are obtained by sampling multiple species within 1 m square area for each soil sample location. Isotopic compositions of samples directly reflect the presence or absence of bullets in the sample area. Anthropogenic Pb in sample locations with abundant bullets display a wide range of ^(206)Pb/^(207)Pb values (1.140–1.234), but relatively less variation in ^(206)Pb/^(208)Pb values (0.473–0.488), which is hypothesized to be reflective of ore-mixing in the manufacture of bullets. Plant samples exhibit a distinction between anthropogenic and natural Pb similar to soil samples, but consistently display lighter ^(206)Pb/^(207)Pb values than soil samples, which is inferred to be representative of the influence of regional atmospheric deposition of contaminant Pb

Conflicting Group Meanings of Territorial Rights in Central Mindanao: Muslim–Christian Social Representations of Land Entitlement

Using a social representations lens, we examined subjective meanings of land entitlements in Central Mindanao among Muslims and Christians. In Study 1, we collected survey data from 231 students from the University of Southern Mindanao in Central Mindanao, asking them: ‘If you were to tell the story of land ownership in Cotabato, what three topics would you want to include in your story?’ Results of our hierarchical evocation analysis show that Christians are concerned with direct conflicts or actual intergroup confrontations while Muslims emphasise land issues. Study 2 implemented Focauldian Discursive Analysis to evaluate two separate focused group discussions by Muslim and Christian village leaders on the question: ‘Who really owns the land in Cotabato, specifically here in Midsayap?’ Findings indicate that Christians hold on to a legal story while Muslims use the ancestral domain narrative to cohere subjective claims to the contested territory. We discuss our results in the light of the role of legalese in an asymmetric territorial conflict and more specifically, the Framework Agreement signed last October 2012 by both the Philippine government and the Moro Islamic Liberation Front

Imagining Unity: The Politics of Transcendence in Donne, Lanyer, Crashaw, and Milton

"Imagining Unity" investigates how an evolving concept of transcendence in early modern England, influenced by Reformation and counter-Reformation theology, created new ways of responding affectively and philosophically to emerging articulations of national identity in British devotional poetry. My project focuses on a series of politically disruptive moments in the seventeenth century--from the residual trauma of the Protestant Reformation to the Civil War of the 1640's--that troubled England's developing sense of national identity. In the shadow of these troubles, devotional poets reworked ideas of transcendence that they had inherited from medieval Catholicism to provide a sense of national cohesion in the midst of a changing political landscape. This dissertation explores transcendence as it is reconceived by four different authors: John Donne's work translates Catholic iconography to symbolize the ascension of a Protestant England; Aemelia Lanyer's poetry appeals to the exclusivity of religious esotericism as a palliative for the actual exclusion of women from political life; Richard Crashaw's writings reinterpret mystical union to rescue sovereignty from failure; and John Milton's work revises transubstantiation to authorize a new republic. By investigating how early modern poetry reimagines transcendence in response to political events, my project widens ongoing conversations in political theology and "the religious turn" of literary studies, which are often unilaterally focused on the influence that religion had on politics in the course of an inevitable secularization of culture. My contribution to this work, and the underlying premise to my argument, is that literature provides a forum for rethinking religious concepts at the heart of political organization despite the apparent impulse toward secularization. In doing so, literature serves as a cultural medium for testing the conceptual limits of transcendence--its viability as a tool for inspiring and maintaining social unity. This dissertation ultimately witnesses a concerted effort in the early modern period to extend the life of religious ideas within the political imagination through devotional poetry's insistent recasting of transcendence as central to the formulation of the body politic

Energy Localization in the Peyrard-Bishop DNA model

We study energy localization on the oscillator-chain proposed by Peyrard and Bishop to model the DNA. We search numerically for conditions with initial energy in a small subgroup of consecutive oscillators of a finite chain and such that the oscillation amplitude is small outside this subgroup for a long timescale. We use a localization criterion based on the information entropy and we verify numerically that such localized excitations exist when the nonlinear dynamics of the subgroup oscillates with a frequency inside the reactive band of the linear chain. We predict a mimium value for the Morse parameter $(\mu >2.25)$ (the only parameter of our normalized model), in agreement with the numerical calculations (an estimate for the biological value is $\mu =6.3$). For supercritical masses, we use canonical perturbation theory to expand the frequencies of the subgroup and we calculate an energy threshold in agreement with the numerical calculations