Long-acting contraceptive agents: Norethisterone esters of polyunsaturated acids

8 pages, 1 scheme.-- PMID: 6658875 [PubMed].Some new derivatives of norethisterone (17α-ethynyl-17β-hydroxyestr-4-en-3-one) are described in which the 17β-hydroxyl group of the steroid is esterified with polyunsaturated aliphatic acids. The potential of these compounds as long-acting contraceptive agents has been evaluated.The authors thank the Special Programme of Research, Development and Research Training in Human Reproduction, World Health Organization, for financial support for this work

Long-acting contraceptive agents: Levonorgestrel esters of unsaturated acids

10 pages, 1 scheme.-- Available online 10 January 2003.Esters of levonorgestrel (13β-ethyl-17β-ethynyl-17β-hydroxygon-4-en-3-one) with a variety of unsaturated carboxylic acids have been synthesized for evaluation as potential long-acting, injectable contraceptive agents.The authors thank the World Health Organization for financial support of this work