Some aspects of therapy on a girl's psychiatric ward

Thesis (M.S.)--Boston University, 195

Thermocurrents and their Role in high Q Cavity Performance

Over the past years it became evident that the quality factor of a superconducting cavity is not only determined by its surface preparation procedure, but is also influenced by the way the cavity is cooled down. Moreover, different data sets exists, some of them indicate that a slow cool-down through the critical temperature is favourable while other data states the exact opposite. Even so there where speculations and some models about the role of thermo-currents and flux-pinning, the difference in behaviour remained a mystery. In this paper we will for the first time present a consistent theoretical model which we confirmed by data that describes the role of thermo-currents, driven by temperature gradients and material transitions. We will clearly show how they impact the quality factor of a cavity, discuss our findings, relate it to findings at other labs and develop mitigation strategies which especially addresses the issue of achieving high quality factors of so-called nitrogen doped cavities in horizontal test

Coherent Moving States in Highway Traffic (Originally: Moving Like a Solid Block)

Recent advances in multiagent simulations have made possible the study of realistic traffic patterns and allow to test theories based on driver behaviour. Such simulations also display various empirical features of traffic flows, and are used to design traffic controls that maximise the throughput of vehicles in heavily transited highways. In addition to its intrinsic economic value, vehicular traffic is of interest because it may throw light on some social phenomena where diverse individuals competitively try to maximise their own utilities under certain constraints. In this paper, we present simulation results that point to the existence of cooperative, coherent states arising from competitive interactions that lead to a new phenomenon in heterogeneous highway traffic. As the density of vehicles increases, their interactions cause a transition into a highly correlated state in which all vehicles practically move with the same speed, analogous to the motion of a solid block. This state is associated with a reduced lane changing rate and a safe, high and stable flow. It disappears as the vehicle density exceeds a critical value. The effect is observed in recent evaluations of Dutch traffic data.Comment: Submitted on April 21, 1998. For related work see http://www.theo2.physik.uni-stuttgart.de/helbing.html and http://www.parc.xerox.com/dynamics

Single-vehicle data of highway traffic - a statistical analysis

In the present paper single-vehicle data of highway traffic are analyzed in great detail. By using the single-vehicle data directly empirical time-headway distributions and speed-distance relations can be established. Both quantities yield relevant information about the microscopic states. Several fundamental diagrams are also presented, which are based on time-averaged quantities and compared with earlier empirical investigations. In the remaining part time-series analyses of the averaged as well as the single-vehicle data are carried out. The results will be used in order to propose objective criteria for an identification of the different traffic states, e.g. synchronized traffic.Comment: 12 pages, 19 figures, RevTe

The Arp2/3 complex is essential for the actin-based motility of Listeria monocytogenes

AbstractActin polymerisation is thought to drive the movement of eukaryotic cells and some intracellular pathogens such as Listeria monocytogenes. The Listeria surface protein ActA synergises with recruited host proteins to induce actin polymerisation, propelling the bacterium through the host cytoplasm [1]. The Arp2/3 complex is one recruited host factor [2,3]; it is also believed to regulate actin dynamics in lamellipodia [4,5]. The Arp2/3 complex promotes actin filament nucleation in vitro, which is further enhanced by ActA [6,7]. The Arp2/3 complex also interacts with members of the Wiskott–Aldrich syndrome protein (WASP) [8] family – Scar1 [9,10] and WASP itself [11]. We interfered with the targeting of the Arp2/3 complex to Listeria by using carboxy-terminal fragments of Scar1 that bind the Arp2/3 complex [11]. These fragments completely blocked actin tail formation and motility of Listeria, both in mouse brain extract and in Ptk2 cells overexpressing Scar1 constructs. In both systems, Listeria could initiate actin cloud formation, but tail formation was blocked. Full motility in vitro was restored by adding purified Arp2/3 complex. We conclude that the Arp2/3 complex is a host-cell factor essential for the actin-based motility of L. monocytogenes, suggesting that it plays a pivotal role in regulating the actin cytoskeleton

Establishing a framework for dynamic risk management in 'intelligent' aero-engine control

The behaviour of control functions in safety critical software systems is typically bounded to prevent the occurrence of known system level hazards. These bounds are typically derived through safety analyses and can be implemented through the use of necessary design features. However, the unpredictability of real world problems can result in changes in the operating context that may invalidate the behavioural bounds themselves, for example, unexpected hazardous operating contexts as a result of failures or degradation. For highly complex problems it may be infeasible to determine the precise desired behavioural bounds of a function that addresses or minimises risk for hazardous operation cases prior to deployment. This paper presents an overview of the safety challenges associated with such a problem and how such problems might be addressed. A self-management framework is proposed that performs on-line risk management. The features of the framework are shown in context of employing intelligent adaptive controllers operating within complex and highly dynamic problem domains such as Gas-Turbine Aero Engine control. Safety assurance arguments enabled by the framework necessary for certification are also outlined

(New) Bulgarian Enlighteners and Ambassadors? The Reinvention of National Identity in Times of Crisis

Drawing on empirical data from 37 Bulgarian students and young professionals in the UK, this article explores the intersection of the discourses produced by the European crises and migrants' national identity. In Bulgaria, the crisis narrative is embedded in the arguably never‐ending democratic transition, manifested in socio‐economic instability and political volatility. Simultaneously, “Brexit Britain” is enveloped in strong Eurosceptic sentiments, propelled by a combination of austerity measures and intensified Eastern European migratory flows. Both contexts subject Bulgarian migrants to stigmatizing representations. Looking at migrants' everyday practices, the data reveals that young Bulgarians draw on the related ideas of the “new” Enlightener and Ambassador to counterbalance negative discourses. Thus, the article explores the meanings and significance attributed to the Enlighteners and the Ambassadors, arguing that the participants engage in “social creativity” and “individual mobility” strategies that lead to reinvention of national identity

Punctuated equilibria and 1/f noise in a biological coevolution model with individual-based dynamics

We present a study by linear stability analysis and large-scale Monte Carlo simulations of a simple model of biological coevolution. Selection is provided through a reproduction probability that contains quenched, random interspecies interactions, while genetic variation is provided through a low mutation rate. Both selection and mutation act on individual organisms. Consistent with some current theories of macroevolutionary dynamics, the model displays intermittent, statistically self-similar behavior with punctuated equilibria. The probability density for the lifetimes of ecological communities is well approximated by a power law with exponent near -2, and the corresponding power spectral densities show 1/f noise (flicker noise) over several decades. The long-lived communities (quasi-steady states) consist of a relatively small number of mutualistically interacting species, and they are surrounded by a ``protection zone'' of closely related genotypes that have a very low probability of invading the resident community. The extent of the protection zone affects the stability of the community in a way analogous to the height of the free-energy barrier surrounding a metastable state in a physical system. Measures of biological diversity are on average stationary with no discernible trends, even over our very long simulation runs of approximately 3.4x10^7 generations.Comment: 20 pages RevTex. Minor revisions consistent with published versio

Collaboration between Science and Religious Education teachers in Scottish Secondary schools

The article reports on quantitative research that examines: (1) the current practice in collaboration; and (2) potential for collaboration between Science and Religious Education teachers in a large sample of Scottish secondary schools. The authors adopt and adapt three models (conflict; concordat and consonance) to interrogate the relationship between science and religion (and the perceived relation between these two subjects in schools) (Astley and Francis 2010). The findings indicate that there is evidence of limited collaboration and, in a few cases, a dismissive attitude towards collaboration (conflict and concordat and very weak consonance). There is, however, evidence of a genuine aspiration for greater collaboration among many teachers (moving towards a more robust consonance model). The article concludes by discussing a number of key factors that must be realised for this greater collaboration to be enacted

Cellular automata approach to three-phase traffic theory

The cellular automata (CA) approach to traffic modeling is extended to allow for spatially homogeneous steady state solutions that cover a two dimensional region in the flow-density plane. Hence these models fulfill a basic postulate of a three-phase traffic theory proposed by Kerner. This is achieved by a synchronization distance, within which a vehicle always tries to adjust its speed to the one of the vehicle in front. In the CA models presented, the modelling of the free and safe speeds, the slow-to-start rules as well as some contributions to noise are based on the ideas of the Nagel-Schreckenberg type modelling. It is shown that the proposed CA models can be very transparent and still reproduce the two main types of congested patterns (the general pattern and the synchronized flow pattern) as well as their dependence on the flows near an on-ramp, in qualitative agreement with the recently developed continuum version of the three-phase traffic theory [B. S. Kerner and S. L. Klenov. 2002. J. Phys. A: Math. Gen. 35, L31]. These features are qualitatively different than in previously considered CA traffic models. The probability of the breakdown phenomenon (i.e., of the phase transition from free flow to synchronized flow) as function of the flow rate to the on-ramp and of the flow rate on the road upstream of the on-ramp is investigated. The capacity drops at the on-ramp which occur due to the formation of different congested patterns are calculated.Comment: 55 pages, 24 figure