90 research outputs found

    Chance of aneurysm in patients suspected of SAH who have a ‘negative’ CT scan but a ‘positive’ lumbar puncture

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    In patients with sudden severe headache and a negative computed tomography (CT) scan, a lumbar puncture (LP) is performed to rule in or out a subarachnoid haemorrhage (SAH), but this procedure is under debate. In a hospital-based series of 30 patients with sudden headache, a negative CT scan but a positive LP (defined as detection of bilirubin >0.05 at wavelength 458 nm), we studied the chance of harbouring an aneurysm and the clinical outcome. Aneurysms were found in none of both patients who presented within 3 days, in 8 of the 18 (44%) who presented within 4–7 days and in 5 of the 10 (50%) who presented within 8–14 days. Of the 13 patients with an aneurysm, 3 (23%) had poor outcome. In patients who present late after sudden headache, the yield in terms of aneurysms is high in those who have a positive lumbar puncture. In patients with an aneurysm as cause of the positive lumbar puncture, outcome is in the same range as in SAH patients admitted in good clinical condition

    Discrepancy between instructor and student evaluations of instruction: Effect on instructor

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    To find out whether a discrepancy between the instructor's and the student's evaluations of teaching influence teaching, 13 introductory and educational psychology instructors and their students were given a Student Opinion Questionnaire (SOQ) twice: on the fourth week of a fall term and eight weeks after feedback sessions with the instructors. The instructors received feedback on the direction and amount of initial discrepancy. The results showed that the unfavorable discrepant instructors (instructor rating better than students) changed more on skill, feedback, rapport, general teaching ability, and the overall value of the course than the favorably discrepant instructors (student ratings better than instructor). The unfavorably discrepant instructors improved their teaching significantly more than the favorably discrepant instructors.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/43863/1/11251_2004_Article_BF00120231.pd

    Stroke in women — from evidence to inequalities

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    Stroke is the second largest cause of disability-adjusted life-years lost worldwide. The prevalence of stroke in women is predicted to rise rapidly, owing to the increasing average age of the global female population. Vascular risk factors differ between women and men in terms of prevalence, and evidence increasingly supports the clinical importance of sex differences in stroke. The influence of some risk factors for stroke — including diabetes mellitus and atrial fibrillation — are stronger in women, and hypertensive disorders of pregnancy also affect the risk of stroke decades after pregnancy. However, in an era of evidence-based medicine, women are notably under-represented in clinical trials — despite governmental actions highlighting the need to include both men and women in clinical trials — resulting in a reduced generalizability of study results to women. The aim of this Review is to highlight new insights into specificities of stroke in women, to plan future research priorities, and to influence public health policies to decrease the worldwide burden of stroke in women

    Arachnids of medical importance in Brazil: main active compounds present in scorpion and spider venoms and tick saliva

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