13,093 research outputs found
Signatures of Spherical Compactification at the LHC
TeV-scale extra dimensions may play an important role in electroweak or
supersymmetry breaking. We examine the phenomenology of such dimensions,
compactified on a sphere , , and show that they possess distinct
features and signatures. For example, unlike flat toroidal manifolds, spheres
do not trivially allow fermion massless modes. Acceptable phenomenology then
generically leads to "non-universal" extra dimensions with "pole-localized"
4- fermions; the bosonic fields can be in the bulk. Due to spherical
symmetry, some Kaluza-Klein (KK) modes of bulk gauge fields are either stable
or extremely long-lived, depending on the graviton KK spectrum. Using precision
electroweak data, we constrain the lightest gauge field KK modes to lie above
TeV. We show that some of these KK resonances are within the reach
of the LHC in several different production channels. The models we study can be
uniquely identified by their collider signatures.Comment: 21 pages, 5 fig
MENGA: a new comprehensive tool for the integration of neuroimaging data and the Allen human brain transcriptome atlas
Brain-wide mRNA mappings offer a great potential for neuroscience research as they can provide information about system proteomics. In a previous work we have correlated mRNA maps with the binding patterns of radioligands targeting specific molecular systems and imaged with positron emission tomography (PET) in unrelated control groups. This approach is potentially applicable to any imaging modality as long as an efficient procedure of imaging-genomic matching is provided. In the original work we considered mRNA brain maps of the whole human genome derived from the Allen human brain database (ABA) and we performed the analysis with a specific region-based segmentation with a resolution that was limited by the PET data parcellation. There we identified the need for a platform for imaging-genomic integration that should be usable with any imaging modalities and fully exploit the high resolution mapping of ABA dataset.In this work we present MENGA (Multimodal Environment for Neuroimaging and Genomic Analysis), a software platform that allows the investigation of the correlation patterns between neuroimaging data of any sort (both functional and structural) with mRNA gene expression profiles derived from the ABA database at high resolution.We applied MENGA to six different imaging datasets from three modalities (PET, single photon emission tomography and magnetic resonance imaging) targeting the dopamine and serotonin receptor systems and the myelin molecular structure. We further investigated imaging-genomic correlations in the case of mismatch between selected proteins and imaging targets
Bosonic Seesaw in the Unparticle Physics
Recently, conceptually new physics beyond the Standard Model has been
proposed by Georgi, where a new physics sector becomes conformal and provides
"unparticle" which couples to the Standard Model sector through higher
dimensional operators in low energy effective theory. Among several
possibilities, we focus on operators involving the (scalar) unparticle, Higgs
and the gauge bosons. Once the Higgs develops the vacuum expectation value
(VEV), the conformal symmetry is broken and as a result, the mixing between the
unparticle and the Higgs boson emerges. In this paper, we consider a natural
realization of bosonic seesaw in the context of unparticle physics. In this
framework, the negative mass squared or the electroweak symmetry breaking
vacuum is achieved as a result of mass matrix diagonalization. In the
diagonalization process, it is important to have zero value in the
(1,1)-element of the mass matrix. In fact, the conformal invariance in the
hidden sector can actually assure the zero of that element. So, the bosonic
seesaw mechanism for the electroweak symmetry breaking can naturally be
understood in the framework of unparticle physics.Comment: 5 pages, no figure; added one more referenc
On Direct Verification of Warped Hierarchy-and-Flavor Models
We consider direct experimental verification of warped models, based on the
Randall-Sundrum (RS) scenario, that explain gauge and flavor hierarchies,
assuming that the gauge fields and fermions of the Standard Model (SM)
propagate in the 5D bulk. Most studies have focused on the bosonic Kaluza Klein
(KK) signatures and indicate that discovering gauge KK modes is likely
possible, yet challenging, while graviton KK modes are unlikely to be
accessible at the LHC, even with a luminosity upgrade. We show that direct
evidence for bulk SM fermions, {\it i.e.} their KK modes, is likely also beyond
the reach of a luminosity-upgraded LHC. Thus, neither the spin-2 KK graviton,
the most distinct RS signal, nor the KK SM fermions, direct evidence for bulk
flavor, seem to be within the reach of the LHC. We then consider hadron
colliders with 21, 28, and 60 TeV. We find that discovering the
first KK modes of SM fermions and the graviton typically requires the Next
Hadron Collider (NHC) with TeV and
ab of integrated luminosity. If the LHC yields hints of these warped
models, establishing that Nature is described by them, or their 4D CFT duals,
requires an NHC-class machine in the post-LHC experimental program.Comment: Revtex4, 21 pages, 11 figure
Collider Production of TeV Scale Black Holes and Higher-Curvature Gravity
We examine how the production of TeV scale black holes at colliders is
influenced by the presence of Lovelock higher-curvature terms in the action of
models with large extra dimensions. Such terms are expected to arise on rather
general grounds, e.g., from string theory and are often used in the literature
to model modifications to the Einstein-Hilbert action arising from quantum
and/or stringy corrections. While adding the invariant which is quadratic in
the curvature leads to quantitative modifications in black hole properties,
cubic and higher invariants are found to produce significant qualitative
changes, e.g., classically stable black holes. We use these higher-order
curvature terms to construct a toy model of the black hole production cross
section threshold. For reasonable parameter values we demonstrate that detailed
measurements of the properties of black holes at future colliders will be
highly sensitive to the presence of the Lovelock higher-order curvature terms.Comment: 37 pages, 11 figures, references adde
Invariant NKT cells and rheumatic disease: Focus on primary sjogren syndrome
Primary Sjogren syndrome (pSS) is a complex autoimmune disease mainly affecting salivary and lacrimal glands. Several factors contribute to pSS pathogenesis; in particular, innate immunity seems to play a key role in disease etiology. Invariant natural killer (NK) T cells (iNKT) are a T-cell subset able to recognize glycolipid antigens. Their function remains unclear, but studies have pointed out their ability to modulate the immune system through the promotion of specific cytokine milieu. In this review, we discussed the possible role of iNKT in pSS development, as well as their implications as future markers of disease activity
Lessons and Prospects from the pMSSM after LHC Run I: Neutralino LSP
We study SUSY signatures at the 7, 8 and 14 TeV LHC employing the
19-parameter, R-Parity conserving p(henomenological)MSSM, in the scenario with
a neutralino LSP. Our results were obtained via a fast Monte Carlo simulation
of the ATLAS SUSY analysis suite. The flexibility of this framework allows us
to study a wide variety of SUSY phenomena simultaneously and to probe for weak
spots in existing SUSY search analyses. We determine the ranges of the
sparticle masses that are either disfavored or allowed after the searches with
the 7 and 8 TeV data sets are combined. We find that natural SUSY models with
light squarks and gluinos remain viable. We extrapolate to 14 TeV with both 300
fb and 3 ab of integrated luminosity and determine the expected
sensitivity of the jets + MET and stop searches to the pMSSM parameter space.
We find that the high-luminosity LHC will be powerful in probing SUSY with
neutralino LSPs and can provide a more definitive statement on the existence of
natural Supersymmetry.Comment: 41 pages, 27 figures. arXiv admin note: substantial text overlap with
arXiv:1307.844
Single Production in Collisions at the NLC
Single production in collisions at the NLC can be used to
probe the Majorana nature of the heavy neutrinos present in the Left-Right
Symmetric Model below the kinematic threshold for their direct production. For
colliders in the TeV range, typical cross sections of order
are obtained, depending on the specific choice of model parameters.
Backgrounds arising from Standard Model processes are shown to be small. This
analysis greatly extends the kinematic range of previous studies wherein the
production of an on-shell, like-sign pair of 's at the NLC was considered.Comment: 13pp, 3 figures (available on request), LaTex, SLAC-PUB-647
Chaos in temperature in the Sherrington-Kirkpatrick model
We prove the existence of chaos in temperature in the
Sherringhton-Kirkpatrick model. The effect is exceedingly small, namely of the
ninth order in perturbation theory. The equations describing two systems at
different temperatures constrained to have a fixed overlap are studied
analytically and numerically, yielding information about the behaviour of the
overlap distribution function in finite-size systems.Comment: REVTEX, 6 pages, 2 figure
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