First Use of Superpulsed Fibre Thulium Laser-Based Contact Stone Ablation in Common Bile and Main Pancreatic Ducts

Aim. A clinical demonstration of the feasibility of novel superpulsed thulium fibre laser in contact intraductal lithotripsy in patients with choledocholithiasis and pancreatic lithiasis.Key points. We describe two clinically successful ablations of large biliary and pancreatic calculi using a FiberLase U2 superpulse fibre thulium laser appliance (IRE-Polus, Russia) during oral transpapillary cholangiopancreaticoscopy in patients with technically unfeasible conventional minimally invasive treatment for choledocho- and pancreatic lithiasis. A 72-yo patient was urgently admitted with acute mechanical jaundice, cholangitis and a history of endoscopic papillosphincterotomy (EPST) and bilioduodenal stenting with a plastic implant for technically impractical lithotripsy and lithoextraction. An ineffective extracorporeal lithotripsy attempt was followed on day 3 by a second retrograde intervention and endoscopic contact laser lithotripsy controlled in oral transpapillary cholangioscopy with FiberLase U2. A 50-yo patient was admitted with clinical signs of chronic calculous pancreatitis and a history of EPST, pancreatic ductotomy and plastic pancreatic stenting. The first endoscopy stage comprised the encrusted pancreatic stent removal, retrograde pancreaticography, pancreatic ductotomy, narrowed terminal Wirsung’s duct bougienage with mechanical dilators and additional balloon-assisted dilation of the excision area and pancreatic stricture. Mechanical intraductal lithotripsy was unsuccessful. Contact lithotripsy with a novel superpulsed fibre thulium laser has been rendered. The technique presented ensures a complete sanation of the duct at no mucosal damage.Conclusion. We present the fully successful first national and world experience of the superpulsed fibre thulium laser application in contact lithotripsy of large calculi in common bile and main pancreatic ducts

The Megapixel EBCCD: a high-resolution imaging tube sensitive to single photons

A hybrid image-intensifier tube, suitable for extremely low-light imaging, has been tested. This device is based on an Electron-Bombarded CCD chip (EBCCD) with $1024 \times 1024$ sensitive pixe ls. The tube, which has a photocathode diameter of 40 mm, is gateable and zoomable, with an image magnification varying from 0.62 to 1.3. The high gain (about 4000 collected electrons per photo electron at the operational voltage of 15 kV) and the relatively low noise (180 electrons per pixel at 10 MHz pixel-readout frequency), allows single-photoelectron signals to be separated from n oise with a signal-to-noise ratio greater than 10. By applying an appropriate threshold on the signal amplitude, the background can almost be eliminated, with a loss of few percent in single-ph otoelectron counting. High inner gain, low noise, single-photoelectron sensitivity, and high spatial resolution make the EBCCD imaging tube a unique device, attractive for many applications in h igh-energy physics, astrophysics, biomedical diagnostics

Description of the two-nucleon system on the basis of the Bargmann representation of the S matrix

For the effective-range function $k\cot \delta$, a pole approximation that involves a small number of parameters is derived on the basis of the Bargmann representation of the $S$ matrix. The parameters of this representation, which have a clear physical meaning, are related to the parameters of the Bargmann $S$ matrix by simple equations. By using a polynomial least-squares fit to the function $k\cot \delta$ at low energies, the triplet low-energy parameters of neutron-proton scattering are obtained for the latest experimental data of Arndt et al. on phase shifts. The results are $a_{t}=5.4030$fm, $r_{t}=1.7494$fm, and $v_{2}=0.163$fm$^{3}$. With allowance for the values found for the low-energy scattering parameters and for the pole parameter, the pole approximation of the function $k\cot \delta$ provides an excellent description of the triplet phase shift for neutron-proton scattering over a wide energy range ($T_{\text{lab}}\lesssim 1000$MeV), substantially improving the description at low energies as well. For the experimental phase shifts of Arndt et al., the triplet shape parameters $v_{n}$ of the effective-range expansion are obtained by using the pole approximation. The description of the phase shift by means of the effective-range expansion featuring values found for the low-energy scattering parameters proves to be fairly accurate over a broad energy region extending to energy values approximately equal to the energy at which this phase shift changes sign, this being indicative of a high accuracy and a considerable value of the effective-range expansion in describing experimental data on nucleon-nucleon scattering. The properties of the deuteron that were calculated by using various approximations of the effective-range function comply well with their experimental values.Comment: 39 pages, 3 figure

Applied Physics Letters

p. 3605-3607The performance of a VO2 thin-film microbolometer has been investigated. The device is operated within 35 °C<T<60 °C, in the hysteretic metal-insulator transition region. An algebraic hysteresis model has been used to model the resistance-temperature characteristic of the sensor. It accurately describes the resistance versus temperature characteristics of the material. Employing this model, and in conjunction with established bolometer theory, the responsivity of a VO2 film is calculated and compared with experimental data. Superior performance of the device is achievable under conditions of single pulse incident radiation where the operating point remains on the major hysteresis loop. This results in a pronounced responsivity peak within the center of the metal-insulator transition. Continuous periodic excitation, in contrast, leads to a steadily decreasing and much lower sensitivity at higher temperature, due to the formation of minor hysteresis loops and the loop accommodation process