89 research outputs found
Estimation des taux de recombinaison entre les locus Phi et Pgd et le complexe SLA chez le porc
International audienc
Estimation des taux de recombinaison entre les locus Phi et Pgd et le complexe SLA chez le porc
Mise en place d'une expérience avec le grand public: entre recherche, vulgarisation et pédagogie
Methodological considerations on implementing a participative experimentWe present the implementation of an economic experiment conducted simultaneously in 11 French cities, with over 2700 participants, during four uninterrupted hours, during a popular-science event held in September 2015. Our goal is both to provide a roadmap for a possible replication and to discuss how the discipline can be used in new fields (science popularization, popular education, public communication)
Immunity Traits in Pigs: Substantial Genetic Variation and Limited Covariation
BACKGROUND: Increasing robustness via improvement of resistance to pathogens is a major selection objective in livestock breeding. As resistance traits are difficult or impossible to measure directly, potential indirect criteria are measures of immune traits (ITs). Our underlying hypothesis is that levels of ITs with no focus on specific pathogens define an individual's immunocompetence and thus predict response to pathogens in general. Since variation in ITs depends on genetic, environmental and probably epigenetic factors, our aim was to estimate the relative importance of genetics. In this report, we present a large genetic survey of innate and adaptive ITs in pig families bred in the same environment. METHODOLOGY/PRINCIPAL FINDINGS: Fifty four ITs were studied on 443 Large White pigs vaccinated against Mycoplasma hyopneumoniae and analyzed by combining a principal component analysis (PCA) and genetic parameter estimation. ITs include specific and non specific antibodies, seric inflammatory proteins, cell subsets by hemogram and flow cytometry, ex vivo production of cytokines (IFNα, TNFα, IL6, IL8, IL12, IFNγ, IL2, IL4, IL10), phagocytosis and lymphocyte proliferation. While six ITs had heritabilities that were weak or not significantly different from zero, 18 and 30 ITs had moderate (0.1<h2≤0.4) or high (h2>0.4) heritability values, respectively. Phenotypic and genetic correlations between ITs were weak except for a few traits that mostly include cell subsets. PCA revealed no cluster of innate or adaptive ITs. CONCLUSIONS/SIGNIFICANCE: Our results demonstrate that variation in many innate and adaptive ITs is genetically controlled in swine, as already reported for a smaller number of traits by other laboratories. A limited redundancy of the traits was also observed confirming the high degree of complementarity between innate and adaptive ITs. Our data provide a genetic framework for choosing ITs to be included as selection criteria in multitrait selection programmes that aim to improve both production and health traits
O trabalho e a saúde de cuidadores de adolescentes com deficiência: uma aproximação a partir do ponto de vista da atividade
Aspectos de complexidade do trabalho de coletores de lixo domiciliar: a gestão da variabilidade do trabalho na rua
Condições de trabalho e transtornos mentais comuns em trabalhadores da rede básica de saúde de Botucatu (SP)
Identification of manganese efficiency candidate genes in winter barley (Hordeum vulgare) using genome wide association mapping
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