Does changing the pulling direction give better insight into biomolecules?

Single molecule manipulation techniques reveal that the mechanical resistance of a protein depends on the direction of the applied force. Using a lattice model of polymers, we show that changing the pulling direction leads to different phase diagrams. The simple model proposed here indicates that in one case the system undergoes a transition akin to the unzipping of a $\beta$ sheet, while in the other case the transition is of a shearing (slippage) nature. Our results are qualitatively similar to experimental results. This demonstrates the importance of varying the pulling direction since this may yield enhanced insights into the molecular interactions responsible for the stability of biomolecules.Comment: RevTeX v4, 10 pages with 6 eps figure

Exchange bias effect and intragranular magnetoresistance in Nd$_{0.84}Sr_{0.16}CoO_3

Electrical transport properties as a function of magnetic field and time have been investigated in polycrystalline, Nd_{0.84}Sr_{0.16}CoO_3. A strong exchange bias (EB) effect is observed associated with the fairly large intragranular magnetoresistance (MR). The EB effect observed in the MR curve is compared with the EB effect manifested in magnetic hysteresis loop. Training effect, described as the decrease of EB effect when the sample is successively field-cycled at a particular temperature, has been observed in the shift of the MR curve. Training effect could be analysed by the successful models. The EB effect, MR and a considerable time dependence in MR are attributed to the intrinsic nanostructure giving rise to the varieties of magnetic interfaces in the grain interior

Pengaruh Promosi dan Citra Merek terhadap Keputusan Pembelian

Tingginya persaingan antar Perusahaan saat ini mengharuskan setiap Perusahaan untuk terus berinovasi dan kreatif dalam menyusun strategi pemasarannya. Salah satu program pemasaran yang efektif dalam mengkomunikasikan produknya adalah melalui program promosi dan citra merek yang positif dibenak konsumen agar dapat membantu konsumen dalam pembuatan keputusan pembeliannya. Penelitian ini bertujuan mengetahui pengaruh promosi yang dilakukan dan citra merek Perusahaan terhadap keputusan pembelian mobil jenis MPV merek Toyota di Kota Denpasar. Purposive sampling adalah teknik sampling yang digunakan dengan responden berjumlah 120 orang dan regresi linear berganda merupakan teknik analisis data yang digunakan. Hasil analisis menunjukkan bahwa, promosi iklan dan citra merek berpengaruh positif signifikan secara parsial dan simultan terhadap keputusan pembelian mobil jenis MPV merek Toyota di Kota Denpasar

Normal mode analysis for scalar fields in BTZ black hole background

We analyze the possibility of inequivalent boundary conditions for a scalar field propagating in the BTZ black hole space-time. We find that for certain ranges of the black hole parameters, the Klein-Gordon operator admits a one-parameter family of self-adjoint extensions. For this range, the BTZ space-time is not quantum mechanically complete. We suggest a physically motivated method for determining the spectra of the Klein-Gordon operator.Comment: 6 pages, no figure, late

Modeling, Design, and Analysis of MagnetoElastic NML Circuits

With the predicted end of CMOS scaling process, researchers started to study several alternative technologies. Among them NanoMagnet Logic (NML) offers advantages complementary to MOS transistors especially for its magnetic nature. Its intrinsic memory capability makes it suitable for zero stand-by power and logic-in-memory applications. NML requires a clock system that, if based on a magnetic field, highly increases the circuit dynamic power consumption. We have recently proposed a solution based on the magnetoelastic effect (ME-NML) [1] and on currently available fabrication processes, which drastically reduces dynamic power consumption. However, many questions still remain unanswered. Which kind of applications are best suited for this technology? How can we effectively design, analyze, and compare ME-NML circuits? Does it really offer advantages over state-of-the-art CMOS transistors? In this paper, we provide answers to all these questions and the results prove that this technology offers indeed extremely good performance. We have designed a Galois field multiplier with a systolic array structure to reduce interconnection overhead. We developed a new RTL model that allows us to easily describe and simulate circuits of any complexity, evaluating at the same time the performance and keeping into account technology constraints. We approach for the first time in the NML scenario the design of ME-NML circuits adopting the standard-cell method used in standard technologies and fulfill the design down to the physical level. The same circuit is designed also with NML technology based on magnetic fields and with a 28 nm low power CMOS bulk technology for comparison. The CMOS circuit is obtained through physical place&route with a commercial tool, providing, therefore, the most accurate comparison ever presented in literature. Power analysis shows that ME-NML circuits have a considerable advantage over both NML and state-of-the-art CMOS bulk technology. As a further by-product results clearly highlight which kind of architectures can better exploit the true potential of NML technology

Self-Adjointness of Generalized MIC-Kepler System

We have studied the self-adjointness of generalized MIC-Kepler Hamiltonian, obtained from the formally self-adjoint generalized MIC-Kepler Hamiltonian. We have shown that for \tilde l=0, the system admits a 1-parameter family of self-adjoint extensions and for \tilde l \neq 0 but \tilde l <{1/2}, it has also a 1-parameter family of self-adjoint extensions.Comment: 11 pages, Latex, no figur

Study of prevalence and socio-demographic determinants of pterygium patients attending at a tertiary care teaching hospital of Western Maharashtra, India

Background: The pterygium is known to cause refractive errors including astigmatism, which can have negative impact on the vision. The present study was carried out to find out the prevalence and socio-demographic determinants of pterygium patients attending Pravara rural hospital, Loni, Maharashtra, India.Methods: A cross-sectional study was conducted in outpatient department of ophthalmology in Pravara rural hospital, Loni. A total of 1910 patients of various ocular morbidities were registered during the studied period in the department of ophthalmology, among these, 100 patients who had pterygium were reviewed. All 100 patients were examined by torch and slit lamp. Data were analysed statistically using percentage and proportions whenever necessary.Results: Out of the 100 pterygium patients, 48% were in the age group of >60 years, followed by 32% in the age group of 51-60 years. In relation to occupation, maximum 82% patients were farm labours followed by 11% were house workers. Majority (62%) having unilateral, while (38%) was having bilateral pterygium. All cases of pterygium were nasal.Conclusion: People who work outdoors are subjected to increase U.V. exposure. So people must be aware of this and they must take appropriate precautions like wearing protective glasses and caps etc.

Possibility of extracting the weak phase γ\gamma from Λb→ΛD0\Lambda_b \to \Lambda D^0 decays

We explore the possibility of extracting the weak phase $\gamma$ from pure tree decays $\Lambda_b \to \Lambda (D^0, \bar{D^0}, D^0_{CP})$ in a model independent way. The CP violating weak phase $\gamma$ can be determined cleanly, without any hadronic uncertainties, as these decay modes are free from the penguin pollutions. Furthermore, neither tagging nor time dependent studies are required to extract the angle $\gamma$ with these modes.Comment: 12 pages, LaTex, Minor changes in the text, version to appear in Phys. Rev.

Role of loop entropy in the force induced melting of DNA hairpin

Dynamics of a single stranded DNA, which can form a hairpin have been studied in the constant force ensemble. Using Langevin dynamics simulations, we obtained the force-temperature diagram, which differs from the theoretical prediction based on the lattice model. Probability analysis of the extreme bases of the stem revealed that at high temperature, the hairpin to coil transition is entropy dominated and the loop contributes significantly in its opening. However, at low temperature, the transition is force driven and the hairpin opens from the stem side. It is shown that the elastic energy plays a crucial role at high force. As a result, the phase diagram differs significantly with the theoretical prediction.Comment: 9 pages, 8 figures; J. Chem. Phys (2011