Examining a reduced jet-medium coupling in Pb+Pb collisions at the Large Hadron Collider

Recent data on the nuclear modification factor $R_{AA}$ of jet fragments in 2.76 ATeV Pb+Pb collisions at the Large Hadron Collider (LHC) indicate that the jet-medium coupling in a Quark-Gluon Plasma (QGP) is reduced at LHC energies and not compatible with the coupling deduced from data at the Relativistic Hadron Collider (RHIC). We estimate the reduction factor from a combined fit to the available data on $R_{AA}(\sqrt{s},p_T,b)$ and the elliptic flow $v_2(\sqrt{s},p_T,b)$ at $\sqrt{s}=0.2,2.76$ ATeV over a transverse momentum range $p_T$ 10-100 GeV and a broad impact parameter, b, range. We use a simple analytic "polytrope" model ($dE/dx=- \kappa E^{a} x^z T^{c}$) to investigate the dynamical jet-energy loss model dependence. Varying a=0-1 interpolates between weakly-coupled and strongly-coupled models of jet-energy dependence while z=0-2 covers a wide range of possible jet-path dependencies from elastic and radiative to holographic string mechanisms. Our fit to LHC data indicates an approximate 40% reduction of the coupling $\kappa$ from RHIC to LHC and excludes energy-loss models characterized by a jet-energy exponent with a>1/3. In particular, the rapid rise of $R_{AA}$ with $p_T$>10 GeV combined with the slow variation of the asymptotic $v_2(p_T)$ at the LHC rules out popular exponential geometric optics models (a=1). The LHC data are compatible with $0\leq a\leq 1/3$ pQCD-like energy-loss models where the jet-medium coupling is reduced by approximately 10% between RHIC and LHC.Comment: 10 pages, 7 figures, version published in Physical Review

Heterodyne detection of CO2 emission lines and wind velocities in the atmosphere of Venus

Strong 10 micrometer line emission from (c-12)(o-16)2 in the upper atmosphere of Venus was detected by heterodyne techniques. Observations of the absolute Doppler shift of the emission features indicate mean zonal wind velocities less than 10 m/sec in the upper atmosphere near the equator. No evidence was found of the 100 m/sec wind velocity implied by the apparent 4-day rotation period of ultraviolet cloud features

The time-dependent localization of Ki 67 antigen-positive cells in human skin wounds

A total of 77 human skin wounds with a post-infliction interval between 3 h and 7 months were investigated and the proliferation marker antigen Ki 67 was visualized in paraffin sections using a specific monoclonal antibody (MIB). The re-built epidermal layer covering the former lesional area showed only a few basal cells positively staining for Ki 67 antigen. No enhanced reactivity was found when compared to uninjured skin. In basal cells of the epidermis adjacent to the wound area, however, varying numbers of positive cells occurred, but no information useful for a reliable time estimation of skin wounds could be obtained due to the considerable variability in the number of Ki 67 positive epidermal basal cells found in non-damaged skin. Fibroblastic cells in the wound area revealed an increased number of Ki 67-positive sites which could first be detected in a 1.5-day-old skin lesion. Positive results could be obtained in every specimen investigated after a post-infliction interval of 6 days up to 1.5 months. Only the scar tissue of the oldest wound examined (wound age 7 months) revealed no increase in the number of positively staining fibroblasts. Therefore, positive results indicate a wound age of at least approximately 1.5 days and the lack of an increased number of positive fibroblastic cells in a sufficient number of specimens indicates at a wound age of less than 6 days, but cannot totally exclude longer post-infliction intervals

Heterodyne detection of CO2 emission lines and wind velocities in the atmosphere of Venus

Strong 10 micrometer line emission from (C-12)(O-16)2 in the upper atmosphere of Venus was detected by heterodyne techniques. Observations of the absolute Doppler shift of the emission features indicate mean zonal wind velocities less than 10 m/sec in the upper atmosphere near the equator. No evidence was found of the 100 m/sec wind velocity implied by the apparent 4-day rotation period of ultraviolet cloud features

Supercollision cooling in undoped graphene

Carrier mobility in solids is generally limited by electron-impurity or electron-phonon scattering depending on the most frequently occurring event. Three body collisions between carriers and both phonons and impurities are rare; they are denoted supercollisions (SCs). Elusive in electronic transport they should emerge in relaxation processes as they allow for large energy transfers. As pointed out in Ref. \onlinecite{Song2012PRL}, this is the case in undoped graphene where the small Fermi surface drastically restricts the allowed phonon energy in ordinary collisions. Using electrical heating and sensitive noise thermometry we report on SC-cooling in diffusive monolayer graphene. At low carrier density and high phonon temperature the Joule power $P$ obeys a $P\propto T_e^3$ law as a function of electronic temperature $T_e$. It overrules the linear law expected for ordinary collisions which has recently been observed in resistivity measurements. The cubic law is characteristic of SCs and departs from the $T_e^4$ dependence recently reported for metallic graphene below the Bloch-Gr\"{u}neisen temperature. These supercollisions are important for applications of graphene in bolometry and photo-detection

Immunohistochemical localization of collagen types I and VI in human skin wounds

A total of 74 human skin wounds were investigated and collagen types I and VI were localized in the wound area by immunohistochemistry. Collagen type I appeared in the form of ramifying string-like structures after approximately 5–6 days, but positive reactions in the form of a spot-like staining around isolated fibroblasts also occurred in a skin wound aged 4 days. Collagen VI was detectable after a post-infliction interval of at least 3 days showing a strongly positive reacting network associated with fibroblasts in the wound area. Both collagens appeared almost constantly after a wound age of 6–7 clays and could also be found in wounds aged a few months. Therefore, although a positive reaction for collagen type I in the form of string-like and ramifying structures around wound fibroblasts indicates a wound age of at least 5–6 days, a spot-like positive staining for collagen type I cannot exclude a wound age of at least 4 days. A positive staining for collagen type VI represents a post-infliction time of 3 days or more. The almost constant appearance of these collagen types suggests that negative results in a sufficient number of specimens indicate a wound age of less than 6–7 days, but cannot completely exclude longer post-infliction intervals. Since collagen type I and VI are also found in the granulation/scar tissue of lesions with advanced wound age, the immunohistochemical analysis of these proteins provides no further information for an age determination of older skin wounds

Graphene microwave transistors on sapphire substrates

We have developed metal-oxide graphene field-effect transistors (MOGFETs) on sapphire substrates working at microwave frequencies. For monolayers, we obtain a transit frequency up to ~ 80 GHz for a gate length of 200 nm, and a power gain maximum frequency of about ~ 3 GHz for this specific sample. Given the strongly reduced charge noise for nanostructures on sapphire, the high stability and high performance of this material at low temperature, our MOGFETs on sapphire are well suited for a cryogenic broadband low-noise amplifier

Hot electron cooling by acoustic phonons in graphene

We have investigated the energy loss of hot electrons in metallic graphene by means of GHz noise thermometry at liquid helium temperature. We observe the electronic temperature T / V at low bias in agreement with the heat diffusion to the leads described by the Wiedemann-Franz law. We report on $T\propto\sqrt{V}$ behavior at high bias, which corresponds to a T4 dependence of the cooling power. This is the signature of a 2D acoustic phonon cooling mechanism. From a heat equation analysis of the two regimes we extract accurate values of the electron-acoustic phonon coupling constant $\Sigma$ in monolayer graphene. Our measurements point to an important effect of lattice disorder in the reduction of $\Sigma$, not yet considered by theory. Moreover, our study provides a strong and firm support to the rising field of graphene bolometric detectors.Comment: 5 figure

Sensitivity of Azimuthal Jet Tomography to Early Time Energy-Loss at RHIC and LHC

We compute the jet path-length dependence of energy-loss for higher azimuthal harmonics of jet-fragments in a generalized model of energy-loss that can interpolate between pQCD and AdS/CFT limits and compare results with Glauber and CGC/KLN initial conditions. We find, however, that even the high-pT second moment is most sensitive to the poorly known early-time evolution during the first fm/c. Moreover, we demonstrate that quite generally the energy and density-dependence leads to an overquenching jet fragments relative to the first LHC $R_{AA}$-data, once the parameters of the energy-loss model are fixed from $R_{AA}$-data at RHIC.Comment: 4 pages, 2 figures, version accepted for publication in J. Phys. G: Nucl. Part. Phys. as conference proceedings for Quark Matter 2011, May 23 - May 28, Annecy, Franc

Repair of large segmental bone defects: BMP-2 gene activated muscle grafts vs. autologous bone grafting

Background: Common cell based strategies for the treatment of osseous defects require the isolation and expansion of autologous cells. Since this makes such approaches time-consuming and expensive, we developed a novel expedited technology creating gene activated muscle grafts. We have previously shown that large segmental bone defects in rats can be regenerated by implantation of muscle tissue fragments activated by BMP-2 gene transfer. Results: In the present study, we compared the bone healing capacities of such gene activated muscle grafts with bone isografts, mimicking autologous bone grafting, the clinical gold standard for treatment of bone defects in patients. Two of 14 male, syngeneic Fischer 344 rats used for this experiment served as donors for muscle and bone. Muscle tissue was harvested from both hind limbs and incubated with an adenoviral vector carrying the cDNA encoding BMP-2. Bone was harvested from the iliac crest and long bone epiphyses. Bone defects (5 mm) were created in the right femora of 12 rats and were filled with either BMP-2 activated muscle tissue or bone grafts. After eight weeks, femora were evaluated by radiographs, micro-computed tomography (mu CT), and biomechanical testing. In the group receiving BMP-2 activated muscle grafts as well as in the bone-grafting group, 100\% of the bone defects were healed, as documented by radiographs and mu CT-imaging. Bone volume was similar in both groups and biomechanical stability of the two groups was statistically indistinguishable. Conclusions: This study demonstrates that treatment of large bone defects by implantation of BMP-2 gene activated muscle tissue leads to similar bone volume and stability as bone isografts, mimicking autologous bone grafting