271 research outputs found
A reappraisal of the Carboniferous macrofloras of the Zonguldak – Amasra Coal Basin, north-western Turkey
The Zonguldak – Amasra Coal Basin in north-western Turkey has Carboniferous terrestrial deposits ranging in age from Arnsbergian to late Asturian or possibly early Cantabrian. They yield macrofloras that allow detailed biostratigraphical correlations with sequences in Europe. These correlations suggest there are substantial gaps in the Zonguldak – Amasra succession, with middle to upper Namurian, upper Langsettian, Duckmantian and lower Asturian strata apparently being missing. This in turn suggests the area was subjected to significant tectonic instability during Pennsylvanian (late Carboniferous) times and that this might have been instrumental in initiating the progressive change in composition and eventual collapse of the coal swamp biome across Variscan Euramerica during Westphalian times.</p
Five narratives of religious itinerary from the Bosomefi and Anowa families of Ian Oguaa in Fanteland, Ghana : a theological exploration of the affinity between the world-view of the Christian scriptures and the African primal world-view.
Thesis (M.Th.)-University of KwaZulu-Natal, Pietermaritzburg, 2005.The purpose of the study is to show the presence of Christ in Fanteland by treating five Fante ancestral and current narratives as analogues of Genesis XIV and interpreting the resulting interpenetrating Scripture and Fante narratives sensus plenior in the manner of Hebrews VII for Fante Christians, revealing the hidden presence of Christ in them. This is made possible by a postulate of an affinity between the Hebrew world view and that of the Fante. What is considered right behaviour in Fanteland is also resonant with the ethics in Hebrews. A section on ethics arising out of the presence of Christ in the narrative follows in each case. The first chapter is introductory giving the aim and objectives of the study the justification, scope and limitations. This is followed by the intellectual framework from secondary sources and the methodology used. In Chapter II there is a comparison of the world view of Hebrews and of Fanteland with a view to seeing their affinity. Chapters III -V give the literary and historical background to each narrative, the narratives themselves and a theological and ethical meditation. In conclusion the fruit of these meditations is summarized and an evaluation is made
A Web-based multimedia collaboratory. Empirical work studies in film archives
This report represents the latest study in the activity on Ecological Information Systems conducted in the Center for Human Machine Interaction situated at Ris National Laboratory and the University of Aarhus. The purpose of this activity is to give a description of the characteristics of work domains that will serve to outline the general context of concern to design of collaboratories. In addition, a set of preliminary implications for the design of a collaboratory are derived from the cognitive work analysis. To anticipate, further research on this approach to the design of collaboratories will show how the preceding analysis is likely to lead to a novel theoretical framework, called Ecological Collaborative Information Systems (ECIS), required for the design of collaboratories. The intention is to illustrate how the general principles of ECIS can be instantiated to develop a concrete design product: A crossdisciplinary and cross-cultural collaboratory to support customer service and professional research in archives. A web based Collaboratory Numerous valuable historic and cultural films and their sources are scattered in various national archives. Knowledge and usage of the multinational film material are severely impeded by access problems. To fully exploit the cultural film heritage internationally, a high degree of cross-disciplinary and international collaboration among professionals working with the film media is required. The Collaboratory for Annotation, Indexing and Retrieval of Digitized Historical Archive Material (Collate) is intended to foster and support collaboration on research, cultural mediation and preservation of films through a distributed multimedia repository. The collaboratory will provide webbased tools and interfac..
Glutamate cycling may drive organic anion transport on the basal membrane of human placental syncytiotrophoblast
The organic anion transporter OAT4 (SLC22A11) and organic anion transporting polypeptide OATP2B1 (SLCO2B1) are expressed in the basal membrane of the placental syncytiotrophoblast. These transporters mediate exchange whereby uptake of one organic anion is coupled to efflux of a counter-ion. In placenta, these exchangers mediate placental uptake of substrates for oestrogen synthesis as well as clearing waste products and xenobiotics from the fetal circulation. However, the identity of the counter-ion driving this transport in the placenta, and in other tissues, is unclear. While glutamate is not a known OAT4 or OATP2B1 substrate, we propose that its high intracellular concentration has the potential to drive accumulation of substrates from the fetal circulation. In the isolated perfused placenta, glutamate exchange was observed between the placenta and the fetal circulation. This exchange could not be explained by known glutamate exchangers. However, glutamate efflux was trans-stimulated by an OAT4 and OATP2B1 substrate (bromosulphothalein). Exchange of glutamate for bromosulphothalein was only observed when glutamate reuptake was inhibited (by addition of aspartate). To determine if OAT4 and/or OATP2B1 mediate glutamate exchange, uptake and efflux of glutamate were investigated in Xenopus laevis oocytes. Our data demonstrate that in Xenopus oocytes expressing either OAT4 or OATP2B1 efflux of intracellular [14C]glutamate could be stimulated by conditions including extracellular glutamate (OAT4), estrone-sulphate and bromosulphothalein (both OAT4 and OATP2B1) or pravastatin (OATP2B1). Cycling of glutamate across the placenta involving efflux via OAT4 and OATP2B1 and subsequent reuptake will drive placental uptake of organic anions from the fetal circulation.<br/
Using Facial Gestures to Drive Narrative in VR
We developed an exploratory VR environment, where spatial features and narratives can be manipulated in real time by the facial and head gestures of the user. We are using the Faceteq prototype, exhibited in 2017, as the interactive interface. Faceteq consists of a wearable technology that can be adjusted on commercial HMDs for measuring facial expressions and biometric responses. Faceteq project was founded with the aim to provide a human-centred additional tool for affective human-computer interaction. The proposed demo will exhibit the hardware and the functionality of the demo in real time
The Free-movement pattern Y-maze:A cross-species measure of working memory and executive function
Numerous neurodegenerative and psychiatric disorders are associated with deficits in executive functions, such as working memory and cognitive flexibility. Progress in developing effective treatments for disorders may benefit from targeting these cognitive impairments, the success of which is predicated on the development of animal models with validated behavioural assays. Zebrafish offer a promising model for studying complex brain disorders, but tasks assessing executive function are lacking. The Free movement pattern (FMP) Ymaze combines aspects of the common Y-maze assay, which exploits the inherent motivation of an organism to explore an unknown environment, with analysis based on a series of sequential two-choice discriminations. We validate the task as a measure of working memory and executive function by comparing task performance parameters in adult zebrafish treated with a range of glutamatergic, cholinergic and dopaminergic drugs known to impair working memory and cognitive flexibility. We demonstrate the cross-species validity of the task by assessing performance parameters in adapted versions of the task for mice and Drosophila, and finally a virtual version in humans, and identify remarkable commonalities between vertebrate species’ navigation of the maze. Together, our results demonstrate that the FMP Y-maze is a sensitive assay for assessing working memory and cognitive flexibility across species from invertebrates to humans, providing a simple and widely applicable behavioural assay with exceptional translational relevance
[Letter to the editor] Telomere fusions associate with coding sequence and copy number alterations in CLL
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FACETEQ interface demo for emotion expression in VR
© 2017 IEEE.Faceteq prototype v.05 is a wearable technology for measuring facial expressions and biometric responses for experimental studies in Virtual Reality. Developed by Emteq Ltd laboratory, Faceteq can enable new avenues for virtual reality research through combination of high performance patented dry sensor technologies, proprietary algorithms and real-time data acquisition and streaming. Emteq founded the Faceteq project with the aim to provide a human-centered additional tool for emotion expression, affective human-computer interaction and social virtual environments. The proposed demonstration will exhibit the hardware and its functionality by allowing attendees to experience three of the showcasing applications we developed this year
FACETEQ; A novel platform for measuring emotion in VR
FaceTeq prototype v.05 is a wearable technology for measuring facial expressions and biometric responses for experimental studies in Virtual Reality. Developed by Emteq Ltd laboratory, FaceTeq can enable new avenues for virtual reality research through combination of high performance patented dry sensor technologies, proprietary algorithms and real-time data acquisition and streaming. FaceTeq project was founded with the aim to provide a human-centred additional tool for emotion expression, affective human-computer interaction and social virtual environments. The proposed poster will exhibit the hardware and its functionality
Moderate early life stress improves adult zebrafish (Danio rerio) working memory but does not affect social and anxiety-like responses
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