Bytes not waves: information communication technologies, global jihadism and counterterrorism

© The Author(s) 2020. Rapoport's conceptualization of the last, religious wave of four global waves remains highly influential. But it, and other typologies, have placed too little emphasis on the influence of information and communication technologies (ICTs) on the evolution of global jihadist activities. This article makes two new contributions by developing both a new ICT-based typology for understanding jihadist evolutions, and by focusing on successful attacks. Our central argument is that ICTs' impact on global jihadism has facilitated dramatic transformations of its strategy, organization and tactics since the 1990s, and that these can be understood as four overlapping iterations. ‘Jihadism 1.0’ describes the hierarchical, top-down directed and overseas financed and trained terrorist organizations that conducted iconic attacks at the turn of the millennium. Jihadism has since evolved into ‘Jihadism 2.0’ and then ‘Jihadism 3.0’. Jihadism 2.0 recognizes that a number of smaller, coordinated attacks can have a global impact. Jihadism 3.0 is inspired terrorism that has no links to the central terror organization, utilizing individuals and crude tactics. Finally, jihadism is evolving toward ‘Jihadism 4.0’, or cyberterrorism. We argue this typology provides a useful basis for scholars and practitioners to conceptualize the ICT dynamics influencing global jihadism, and these may be applicable to other global terrorists. The conclusion analyses how counter-terrorism services can respond to these evolutions and charts areas for future research.UK Research and Innovation Future Leaders Fellowship grant reference MR/S034412/1 and the GLOBSEC Intelligence Reform Initiativ

TNF-dependent regulation and activation of innate immune cells are essential for host protection against cerebral tuberculosis

BACKGROUND: Tuberculosis (TB) affects one third of the global population, and TB of the central nervous system (CNS-TB) is the most severe form of tuberculosis which often associates with high mortality. The pro-inflammatory cytokine tumour necrosis factor (TNF) plays a critical role in the initial and long-term host immune protection against Mycobacterium tuberculosis (M. tuberculosis) which involves the activation of innate immune cells and structure maintenance of granulomas. However, the contribution of TNF, in particular neuron-derived TNF, in the control of cerebral M. tuberculosis infection and its protective immune responses in the CNS were not clear. METHODS: We generated neuron-specific TNF-deficient (NsTNF / ) mice and compared outcomes of disease against TNF f/f control and global TNF / mice. Mycobacterial burden in brains, lungs and spleens were compared, and cerebral pathology and cellular contributions analysed by microscopy and flow cytometry after M. tuberculosis infection. Activation of innate immune cells was measured by flow cytometry and cell function assessed by cytokine and chemokine quantification using enzyme-linked immunosorbent assay (ELISA). RESULTS: Intracerebral M. tuberculosis infection of TNF / mice rendered animals highly susceptible, accompanied by uncontrolled bacilli replication and eventual mortality. In contrast, NsTNF / mice were resistant to infection and presented with a phenotype similar to that in TNF f/f control mice. Impaired immunity in TNF / mice was associated with altered cytokine and chemokine synthesis in the brain and characterised by a reduced number of activated innate immune cells. Brain pathology reflected enhanced inflammation dominated by neutrophil influx. CONCLUSION: Our data show that neuron-derived TNF has a limited role in immune responses, but overall TNF production is necessary for protective immunity against CNS-TB

Cognitive architecture for perception-reaction intelligent computer agents (CAPRICA)

In this paper, we introduce a cognitive agent architecture that can be used in the study of Human-Robot Interaction. The Cognitive Architecture for Perception-Reaction Intelligent Computer Agents (CAPRICA) is an extensible agent library built around the ideas of theory of mind, episodic memory, and embodied cognition. Existing agent research in each of these areas was used to formulate design requirements. We provide an overview of the library\u27s design and discuss future work in progress