2 research outputs found
Extremely Slow Dynamics of an Abiotic Helical Assembly: Unusual Relevance to the Secondary Structure of Proteins
Serendipitously, we found that isoleucine methylester
functionalized
perylenediimide <b>1</b> undergoes an extremely slow supramolecular
helical assembly over a day’s time. Surprisingly, heating led
to irreversible chiral denaturation. However, reversible helical assembly
could be achieved only in the presence of nondenatured aggregates
of <b>1</b>, which act as seeds. The intriguing functional relevance
deduced from <b>1</b> was employed to draw parallels with the
secondary structure of proteins, envisaging its plausible implications
Molecular Architectonics of Naphthalenediimides for Efficient Structure–Property Correlation
We present a bioinspired design strategy
to effectively tailor the assembly of naphthalenediimides (NDIs) into
a wide variety of architectures by functionalizing with amino acid
derivatives. This bioinspired process of custom designing and engineering
molecular assemblies is termed “bioinspired architectonics”.
By employing minute structural mutations in the form of α-substituents
of amino acids, we successfully engineered molecular assembly of NDIs
into zero-dimensional (0D, spheres), one-dimensional (1D, fibers),
and two-dimensional (2D, sheets) architectures. The 2D sheets of phenylalanine
methylester appended NDI <b>1</b> showed remarkable bulk electron
mobility of up to 1 cm<sup>2</sup> V<sup>–1</sup>s<sup>–1</sup>. With the aid of photophysical, diffraction, and microscopy techniques
we rationalize the effect of molecular structure with their ordering
and electronic properties in an effort to find structure–property
correlations via a bioinspired modular approach