639 research outputs found
Interfertility between Armillaria cepistipes and A. sinapina
Des Ă©tudes ont rapportĂ© que des lignĂ©es europĂ©ennes d'Armillaria cepistipes Ă©taient interfertiles avec trois lignĂ©es amĂ©ricaines d'Armillaria dĂ©signĂ©es par les termes espĂšce biologique nord-amĂ©ricaine (NABS) V (A sinapina), NABS X et NABS XI. Une telle interfertilitĂ© entre les espĂšces soulĂšve des doutes au sujet de l'utilisation de binĂŽmes latins distincts pour des espĂšces pouvant se reproduire. Cette interfertilitĂ© a Ă©tĂ© rĂ©-examinĂ©e en mettant 24 isolats haploĂŻdes d'A cepistipes europĂ©en en prĂ©sence de 23 isolats 6'A. sinapina d'AmĂ©rique du Nord et d'Asie. Les appariements individuels ont Ă©tĂ© effectuĂ©s de façon indĂ©pendante au moins une fois Ă l'UniversitĂ© Laval (Canada) et Ă NNRA Clermont-Ferrand (France). Des 420 appariements interspĂ©cifiques effectuĂ©s Ă l'UniversitĂ© Laval, deux Ă©taient positifs et sept Ă©taient ambigus, pour un total de 2,1 % de tous les appariements. Des 506 appariements effectuĂ©s Ă Clermont-Ferrand, 10 Ă©taient positifs et 24 Ă©taient ambigus pour un total de 6,7 % des appariements. Les diffĂ©rences dans les rĂ©sultats de ces appariements peuvent ĂȘtre expliquĂ©es par les tempĂ©ratures d'incubation, ainsi que par les diffĂ©rents types et concentrations d'extrait de malt utilisĂ©s dans chaque laboratoire. Les bas niveaux d'interfertilitĂ© trouvĂ©s entre A cepistipes et A. sinapina peuvent rĂ©sulter de l'absence de barriĂšres gĂ©nĂ©tiques habituellement prĂ©sentes entre des espĂšces sympatriques. Ce bas niveau d'interfertilitĂ© reflĂšte des diffĂ©rences entre la morphologie, la rĂ©partition et les habitats des deux espĂšces d'Armillaria, et appuie la conservation de dĂ©nominations d'espĂšces distinctes.European strains of Armillaria cepistipes were reported to be interfertile with strains from three American Armillaria species known as North American Biological Species (NABS) V (A sinapina), NABS X and NABS XI. Such interfertility between species raises some doubts about using different Latin binomials for species capable of mating. This interfertility was reinvestigated by mating 24 haploid isolates of European A cepistipes with 23 isolates of A sinapinafrom North America and Asia. Individual pairings were independently performed at least once at Universite Laval, Canada and at INRA Clermont-Ferrand, France. From the 420 interspecific pairings performed at Laval, two were positive and seven were ambiguous for a total of 2.1% of all the pairings. From the 506 pairings made at Clermont-Ferrand, 10 were positive and 24 were ambiguous for a total of 6.7%. The differences in the pairing results may be explained by incubation temperatures, and the different types and concentrations of malt extract used at each laboratory. The low levels of interfertility found between A. cepistipes and A. sinapina may result from the absence of genetic barriers that are usually present between sympatric species. This low level of interfertility reflects differences in morphology, distribution, and habitat for these two species of Armillaria and this supports the retention of different species denominations
The effect of tailored Web-based interventions on pain in adults: a systematic review protocol
QOZs in the Big Easy: A Study of Qualified Opportunity Zones in New Orleans
The MURP 4005/5005 Introduction to Neighborhood Planning course provided service learning to HousingNOLA. HousingNOLA focuses on issues that relate to housing, employment, socio-economic development, community engagement, public policy and strategic uses of data to empower individuals and enrich the non-profit, public and private sectors. The course provided an introduction to neighborhood issues that HousingNOLA cares about and strives to make better: community involvement in the planning process. The focus of the project research was on US Federal Qualified Opportunity Zones (QOZ) and how this national policy has been deployed in both New Orleans, LA.
The research report will serve as a âfirst lookâ at NOLA QOZs from the national to state to local perspectives. The NOLA QOZ report will be shared with the City of New Orleans Municipal Offices and the New Orleans Business Alliance who is leading the development of a QOZ strategic plan. UNO Students identified and tested free public and private geospatial analysis and map making services. The students have shared guides to online mapping resources to summarize the conditions, and create a profile, of the QOZ that was âadoptedâ for the class
Invariant vector fields and the prolongation method for supersymmetric quantum systems
The kinematical and dynamical symmetries of equations describing the time
evolution of quantum systems like the supersymmetric harmonic oscillator in one
space dimension and the interaction of a non-relativistic spin one-half
particle in a constant magnetic field are reviewed from the point of view of
the vector field prolongation method. Generators of supersymmetries are then
introduced so that we get Lie superalgebras of symmetries and supersymmetries.
This approach does not require the introduction of Grassmann valued
differential equations but a specific matrix realization and the concept of
dynamical symmetry. The Jaynes-Cummings model and supersymmetric
generalizations are then studied. We show how it is closely related to the
preceding models. Lie algebras of symmetries and supersymmetries are also
obtained.Comment: 37 pages, 7 table
Regulation of c-Raf stability through the CTLH complex
c-Raf is a central component of the extracellular signal-regulated kinase (ERK) pathway which is implicated in the development of many cancer types. RanBPM (Ran-Binding Protein M) was previously shown to inhibit c-Raf expression, but how this is achieved remains unclear. RanBPM is part of a recently identified E3 ubiquitin ligase complex, the CTLH (C-terminal to LisH) complex. Here, we show that the CTLH complex regulates c-Raf expression through a control of its degradation. Several domains of RanBPM were found necessary to regulate c-Raf levels, but only the C-terminal CRA (CT11-RanBPM) domain showed direct interaction with c-Raf. c-Raf ubiquitination and degradation is promoted by the CTLH complex. Furthermore, A-Raf and B-Raf protein levels are also regulated by the CTLH complex, indicating a common regulation of Raf family members. Finally, depletion of CTLH subunits RMND5A (required for meiotic nuclear division 5A) and RanBPM resulted in enhanced proliferation and loss of RanBPM promoted tumour growth in a mouse model. This study uncovers a new mode of control of c-Raf expression through regulation of its degradation by the CTLH complex. These findings also uncover a novel target of the CTLH complex, and suggest that the CTLH complex has activities that suppress cell transformation and tumour formation
Loss of ATRX in Chondrocytes Has Minimal Effects on Skeletal Development
BACKGROUND:Mutations in the human ATRX gene cause developmental defects, including skeletal deformities and dwarfism. ATRX encodes a chromatin remodeling protein, however the role of ATRX in skeletal development is currently unknown. METHODOLOGY/PRINCIPAL FINDINGS:We induced Atrx deletion in mouse cartilage using the Cre-loxP system, with Cre expression driven by the collagen II (Col2a1) promoter. Growth rate, body size and weight, and long bone length did not differ in Atrx(Col2cre) mice compared to control littermates. Histological analyses of the growth plate did not reveal any differences between control and mutant mice. Expression patterns of Sox9, a transcription factor required for cartilage morphogenesis, and p57, a marker of cell cycle arrest and hypertrophic chondrocyte differentiation, was unaffected. However, loss of ATRX in cartilage led to a delay in the ossification of the hips in some mice. We also observed hindlimb polydactily in one out of 61 mutants. CONCLUSIONS/SIGNIFICANCE:These findings indicate that ATRX is not directly required for development or growth of cartilage in the mouse, suggesting that the short stature in ATR-X patients is caused by defects in cartilage-extrinsic mechanisms
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