17 research outputs found
Some Unusual Properties of Turbulent Convection and Dynamos in Rotating Spherical Shells
The dynamics of convecting fluids in rotating spherical shells is governed at
Prandtl numbers of the order unity by the interaction between differential
rotation and roll-like convection eddies. While the differential rotation is
driven by the Reynolds stresses of the eddies, its shearing action inhibits
convection and causes phenomena such as localized convection and turbulent
relaxation oscillations. The response of the system is enriched in the case of
dynamo action. Lorentz forces may brake either entirely or partially the
geostrophic differential rotation and give rise to two rather different dynamo
states. Bistability of turbulent dynamos exists for magnetic Prandtl numbers of
the order unity. While the ratios between mean magnetic and kinetic energies
differ by a factor of 5 or more for the two dynamo states, the mean convective
heat transports are nearly the same. They are much larger than in the absence
of a magnetic field.Comment: To appear in Procs. IUTAM Symposium on Turbulence in the Atmosphere
and Oceans, 08-7 = GA.06-0
Patterns of convection in rotating spherical shells
Patterns of convection in internally heated, self-gravitating rotating
spherical fluid shells are investigated through numerical simulations. While
turbulent states are of primary interest in planetary and stellar applications
the present paper emphasizes more regular dynamical features at Rayleigh
numbers not far above threshold which are similar to those which might be
observed in laboratory or space experiments. Amplitude vacillations and spatial
modulations of convection columns are common features at moderate and large
Prandtl numbers. In the low Prandtl number regime equatorially attached
convection evolves differently with increasing Rayleigh number and exhibits an
early transition into a chaotic state. Relationships of the dynamical features
to coherent structures in fully turbulent convection states are emphasized
Novel imino sugar α-glucosidase inhibitors as antiviral drugs
International audienc
Selection of the biological activity of DNJ neoglycoconjugates through click length variation of the side chain.
A series of neoglycoconjugates derived from deoxynojirimycin has been prepared by click connection with functionalised adamantanes. They have been assayed as glycosidase inhibitors, as inhibitors of the glycoenzymes relevant to the treatment of Gaucher disease, as well as correctors of the defective ion-transport protein involved in cystic fibrosis. We have demonstrated that it is possible to selectively either strongly inhibit ER-α-glucosidases and ceramide glucosyltransferase or restore the activity of CFTR in CF-KM4 cells by varying the length of the alkyl chain linking DNJ and adamantane