4 research outputs found

    Category-specific naming impairment in temporal lobe epilepsy through cortical electrical stimulation: Case report

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    Current studies based on specific naming subcategories are scarce and specially if they are combined with cortical electrical stimulation mapping (CES). Most researchers use generic categories of objects that have not shown to be useful for epileptic patients. The present study explores the ability to retrieve words with the aim of naming entities through CES during surgery of a patient with left temporal lobe epilepsy (TLE) prior to anterior temporal lobectomy (ATL). During the CES we observed alterations in the naming of faces, living things (LTh) and parts of the body, with conservation of non-living things (NLTh). CES allowed the identification and prediction of regions at risk of being resected. This result shows that the naming deficits are selective and can be used as indicators and predictors of post-operative cognitive dysfunction in TLE since the regions involved in this function are associated with the pole and inferior and medial temporal gyrus. Resumen: Actualmente los estudios de subcategorías en la denominación son escasos y más cuando se combinan con estimulación eléctrica cortical directa (EEC). La mayoría usa objetos que no han mostrado ser específicos en epilepsia del lóbulo temporal (ELT). El presente estudio explora la recuperación de las palabras con el objetivo de nombrar entidades (denominación) a través de la EEC durante la cirugía de una paciente con ELT-izquierdo previo a la lobectomía temporal anterior (LTA) Durante la estimulación se observaron alteraciones en la denominación de rostros, seres vivos (SV) animados y partes del cuerpo, con conservación de los seres no vivos (SNV). La EEC permitió identificar y predecir las regiones con riesgo de ser resecadas. Este resultado muestra que las alteraciones en la denominación son selectivas por lo que pueden emplearse como predictores de disfunción cognitiva postquirúrgica, ya que esta función depende de polo y giro temporal inferior y medial. Keywords: Naming, Cortical electrical stimulation mapping, Language, Temporal lobe epilepsy, Palabras clave: Denominación, Estimulación eléctrica cortical directa, Lenguaje, Epilepsia del lóbulo tempora

    Stress neuropeptide levels in adults with chest pain due to coronary artery disease: potential implications for clinical assessment

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    : Substance P (SP) and neuropeptide Y (NPY) are neuropeptides involved in nociception. The study of biochemical markers of pain in communicating critically ill coronary patients may provide insight for pain assessment and management in critical care. Purpose of the study was to to explore potential associations between plasma neuropeptide levels and reported pain intensity in coronary critical care adults, in order to test the reliability of SP measurements for objective pain assessment in critical care
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