13 research outputs found
Novi steroidni derivati sintetizirani iz 3betha-hidroksiandrosten-17-ona
Get PDFIn this study, we synthesized some new substituted steroidal derivatives using 3betha-hydroxyandrosten-17-one (dehydroepiandrosterone) as starting material. The synthesized steroidal derivatives 1-11 were evaluated for their androgenic-anabolic activities compared to testosterone as positive control. Details of the synthesis, spectroscopic data and toxicity (LD50) of synthesized compounds are reported.U radu je opisana sinteza novih steroidnih derivata 1-11 koristeći 3betha-hidroksiandrosten-17-on (dehidroepiandrosteron) kao početnu supstanciju. Androgeno-anaboličko djelovanje tih spojeva uspoređivano je s djelovanjem testosterona kao pozitivnom kontrolom. Navode se detaljni sintetski postupci, spektroskopska karakterizacija i podaci o toksičnosti (LD50)
Caspases, DNA fragmentation, and oxidative stress: implications for the pathogenesis of preeclamsia and relationship with the maternal risk factors and perinatal outcome
No full textNo Abstract. The Egyptian Journal of Biochemistry and Molecular Biology Vol. 23(2) 2005: 105-12
Synthesis and reactions of thiosemicarbazides, triazoles, and Schiff bases as antihypertensive α-blocking agents
No full textAntianexiety activity of pyridine derivatives synthesized from 2-chloro-6-hydrazino-isonicotinic acid hydrazide
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Changes in the amount of reduced glutathione and activity of antioxidant enzymes in chosen mouse organs influenced by zymosan and melatonin administration
No full textAndrogen Receptor Antagonists and Anti-prostate Cancer Activities of Some Synthesized Steroidal Candidates
No full textEvaluation of 3-(4′-(4″-fluorophenyl)-6′-phenylpyrimidin-2′-yl)-2-phenylthiazolidin-4-one for in vivo
No full textChanges of Oxidative Stress, Glutathione, and Its Dependent Antioxidant Enzyme Activities in Patients with Hepatocellular Carcinoma before and after Tumor Resection
No full textGlutathione-dependent formaldehyde dehydrogenase (ADH3) and low km mitochondrial aldehyde dehydrogenase (ALDH2). New evidence for differential expression in the rat retina in response to oxidative stress
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