18 research outputs found
Ultrasound diagnosis of iliac lymph node metastases in cancer of the cervix uteri
The Outpatient Ultrasound Diagnosis Group, Research Consulting Department, N. N. Blokhin Russian Cancer Research Center, studied theΒ results of an examination in 93 patients with the verified diagnosis of cancer of the cervix uteri (CCU). To specify the extent of a tumor process,Β a comprehensive ultrasound examination was made in all the patients with verified CCU during their first visit. Our findings were statisticallyΒ processed. According to our findings, ultrasound computed tomography is a highly informative method to diagnose retroperitoneal lymph nodeΒ (LN) metastases, which defines the shape, sizes, structure, location, and number of metastatic LNs. Iliac LNs with reactive changes wereΒ detected in 24.7 % of CCU cases. No ultrasound signs of iliac LN metastatic involvement were found in 4.3 % of cases in the presence of CCUΒ micrometastases. The number of metastatic regional LNs was validly proven to increase with larger tumor sizes. The threshold values of cervicaltumors were determined, which may presume the presence or absence of iliac LN metastases to have a rather high sensitivity and specificity.Β The risk of LN metastatic involvement was validly proven to be 4.1-fold higher with greater two or more threshold values of a cervicalΒ tumor
PLACE OF ECHOGRAPHY IN SPECIFYING APPROACHES TO TREATING OVARIAN CANCER
The results of ultrasound study and surgical treatment in 248 patients aged 20 to 78 years who had ovarian epithelial malignancies were the subject of this investigation that has provided evidence that ultrasonic tomography is currently the leading imaging technique that allows specification of the ovarian cancer spread pattern and, depending on this, elaboration of adequate treatment policy
ΠΠ½Π°Π»ΠΈΠ· ΡΡ ΠΎΠ³ΡΠ°ΡΠΈΡΠ΅ΡΠΊΠΈΡ ΠΏΡΠΈΠ·Π½Π°ΠΊΠΎΠ² ΠΎΠΏΡΡ ΠΎΠ»Π΅ΠΉ ΡΠΈΡΠ½ΠΈΠΊΠΎΠ²
Purpose: analysis of echographic signs of benign and malignant formations of the uterine appendages using the recommendations of the IOTA group.Materials and methods. 17 articles published in the journal Ultrasound in Obstetrics & Gynecology for 2007β2020 were analyzed. Each article is devoted to the histologically verified pathology of the uterine appendages, of which 431 are benign and 1205 are malignant neoplasms. When describing pathological formations, the re-searchers used a single protocol recommended by the IOTA group. 21 parameters were assessed, including the morphology of the formation, the structure of fluid inclusions and solid component, the presence of fluid in the posterior uterine pocket and ascites, as well as the degree of tumor vascularization.Results. Πll ultrasound signs of tumors were found in both groups, but the frequency of their occurrence was different. Thus, unilocular neoplasms were more often detected in benign tumors than in malignant ones (p = 0.05). Also, acoustic shadows were found significantly more frequently in benign tumors (p < 0.05). When assessing tumor morphology, attention should be paid to tendencies that are more characteristic of malignant tumors, which include a solid structure (p = 0.13) and the occurrence of ascites (p = 0.13), while a multilocular structure without a solid component was more common in benign (p = 0.10). The size of the neoplasm, uneven contour, papillary growths, hyperechoic inclusions and the nature of the internal contents of the cystic cavities are found with approximately the same frequency in both groups. When as-sessing the blood supply to a pathological formation, hypervascularization confidently indicated a malignant tumor (p < 0.05), while avascularization in such neoplasms was rare, however, the differences with benign ones were insignificant (p = 0.06).Conclusions. There are no reliable echographic signs of the nature of the neo-plasm. The set of criteria will improve the quality of preoperative ultrasound diagnostics of ovarian tumors.Π¦Π΅Π»Ρ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ: Π°Π½Π°Π»ΠΈΠ· ΡΡ
ΠΎΠ³ΡΠ°ΡΠΈΡΠ΅ΡΠΊΠΈΡ
ΠΏΡΠΈΠ·Π½Π°ΠΊΠΎΠ² Π΄ΠΎΠ±ΡΠΎΠΊΠ°ΡΠ΅ΡΡΠ²Π΅Π½Π½ΡΡ
ΠΈ Π·Π»ΠΎΠΊΠ°ΡΠ΅ΡΡΠ²Π΅Π½Π½ΡΡ
ΠΎΠ±ΡΠ°Π·ΠΎΠ²Π°Π½ΠΈΠΉ ΠΏΡΠΈΠ΄Π°ΡΠΊΠΎΠ² ΠΌΠ°ΡΠΊΠΈ Ρ ΠΏΡΠΈΠΌΠ΅Π½Π΅Π½ΠΈΠ΅ΠΌ ΡΠ΅ΠΊΠΎΠΌΠ΅Π½Π΄Π°ΡΠΈΠΉ Π³ΡΡΠΏΠΏΡ IOTA.ΠΠ°ΡΠ΅ΡΠΈΠ°Π» ΠΈ ΠΌΠ΅ΡΠΎΠ΄Ρ. ΠΡΠΎΠ°Π½Π°Π»ΠΈΠ·ΠΈΡΠΎΠ²Π°Π½Ρ 17 ΡΡΠ°ΡΠ΅ΠΉ, ΠΎΠΏΡΠ±Π»ΠΈΠΊΠΎΠ²Π°Π½Π½ΡΡ
Π² ΠΆΡΡΠ½Π°Π»Π΅ Ultrasound in Obstetrics & Gynecology Π·Π° 2007β2020 Π³Π³. ΠΠ°ΠΆΠ΄Π°Ρ ΡΡΠ°ΡΡΡ ΠΏΠΎΡΠ²ΡΡΠ΅Π½Π° Π°Π½Π°Π»ΠΈΠ·Ρ ΡΠ»ΡΡΡΠ°Π·Π²ΡΠΊΠΎΠ²ΠΎΠ³ΠΎ ΠΈΠ·ΠΎΠ±ΡΠ°ΠΆΠ΅Π½ΠΈΡ ΡΠ°Π·Π»ΠΈΡΠ½ΠΎΠΉ Π³ΠΈΡΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈ Π²Π΅ΡΠΈΡΠΈΡΠΈΡΠΎΠ²Π°Π½Π½ΠΎΠΉ ΠΏΠ°ΡΠΎΠ»ΠΎΠ³ΠΈΠΈ ΠΏΡΠΈΠ΄Π°ΡΠΊΠΎΠ² ΠΌΠ°ΡΠΊΠΈ, Π³Π΄Π΅ 431 β Π΄ΠΎΠ±ΡΠΎΠΊΠ°ΡΠ΅ΡΡΠ²Π΅Π½Π½ΡΠ΅ ΠΈ 1205 β Π·Π»ΠΎΠΊΠ°ΡΠ΅ΡΡΠ²Π΅Π½Π½ΡΠ΅ Π½ΠΎΠ²ΠΎΠΎΠ±ΡΠ°Π·ΠΎΠ²Π°Π½ΠΈΡ. ΠΡΠΈ ΠΎΠΏΠΈΡΠ°Π½ΠΈΠΈ ΠΏΠ°ΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ
ΠΎΠ±ΡΠ°Π·ΠΎΠ²Π°Π½ΠΈΠΉ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°ΡΠ΅Π»ΠΈ ΠΈΡΠΏΠΎΠ»Ρ Π·ΠΎΠ²Π°Π»ΠΈ Π΅Π΄ΠΈΠ½ΡΠΉ ΠΏΡΠΎΡΠΎΠΊΠΎΠ», ΡΠ΅ΠΊΠΎΠΌΠ΅Π½Π΄ΠΎΠ²Π°Π½Π½ΡΠΉ Π³ΡΡΠΏΠΏΠΎΠΉ IOTA. ΠΡΠ΅Π½ΠΈΠ²Π°Π»ΠΈ 21 ΠΏΠ°ΡΠ°ΠΌΠ΅ΡΡ, Π²ΠΊΠ»ΡΡΠ°ΡΡΠΈΠΉ ΡΠ»ΡΡΡΠ°Π·Π²ΡΠΊΠΎΠ²ΠΎΠ΅ ΡΡΡΠΎΠ΅Π½ΠΈΠ΅ ΠΎΠ±ΡΠ°Π·ΠΎΠ²Π°Π½ΠΈΡ, ΡΡΡΡΠΊΡΡΡΡ ΠΆΠΈΠ΄ΠΊΠΎΡΡΠ½ΡΡ
Π²ΠΊΠ»ΡΡΠ΅Π½ΠΈΠΉ ΠΈ ΡΠΎΠ»ΠΈΠ΄Π½ΠΎΠ³ΠΎ ΠΊΠΎΠΌΠΏΠΎΠ½Π΅Π½ΡΠ°, Π½Π°Π»ΠΈΡΠΈΠ΅ ΠΆΠΈΠ΄ΠΊΠΎΡΡΠΈ Π² ΠΏΠΎΠ·Π°Π΄ΠΈΠΌΠ°ΡΠΎΡΠ½ΠΎΠΌ ΠΏΡΠΎΡΡΡΠ°Π½ΡΡΠ²Π΅ ΠΈ Π°ΡΡΠΈΡ, Π° ΡΠ°ΠΊΠΆΠ΅ ΡΡΠ΅ΠΏΠ΅Π½Ρ Π²Π°ΡΠΊΡΠ»ΡΡΠΈΠ·Π°ΡΠΈΠΈ ΠΎΠΏΡΡ
ΠΎΠ»ΠΈ.Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ. ΠΡΠ΅ ΡΠ»ΡΡΡΠ°Π·Π²ΡΠΊΠΎΠ²ΡΠ΅ ΠΏΡΠΈΠ·Π½Π°ΠΊΠΈ ΠΎΠΏΡΡ
ΠΎΠ»Π΅ΠΉ Π±ΡΠ»ΠΈ ΠΎΠ±Π½Π°ΡΡΠΆΠ΅Π½Ρ Π² ΠΎΠ±Π΅ΠΈΡ
Π³ΡΡΠΏΠΏΠ°Ρ
, Π½ΠΎ ΡΠ°ΡΡΠΎΡΠ° ΠΈΡ
Π²ΡΡΡΠ΅ΡΠ°Π΅ΠΌΠΎΡΡΠΈ ΠΎΠΊΠ°Π·Π°Π»Π°ΡΡ ΡΠ°Π·Π»ΠΈΡΠ½ΠΎΠΉ. Π’Π°ΠΊ, ΠΎΠ΄Π½ΠΎΠΊΠ°ΠΌΠ΅ΡΠ½ΡΠ΅ Π½ΠΎΠ²ΠΎΠΎΠ±ΡΠ°Π·ΠΎΠ²Π°Π½ΠΈΡ ΡΠ°ΡΠ΅ Π²ΡΡΠ²Π»Π΅Π½Ρ Π² Π΄ΠΎΠ±ΡΠΎΠΊΠ°ΡΠ΅ΡΡΠ²Π΅Π½Π½ΡΡ
ΠΎΠΏΡΡ
ΠΎΠ»ΡΡ
, ΡΠ΅ΠΌ Π² Π·Π»ΠΎΠΊΠ°ΡΠ΅ΡΡΠ²Π΅Π½Π½ΡΡ
(p = 0,05). Π’Π°ΠΊΠΆΠ΅ Π² Π΄ΠΎΠ±ΡΠΎΠΊΠ°ΡΠ΅ΡΡΠ²Π΅Π½Π½ΡΡ
ΠΎΠΏΡΡ
ΠΎΠ»ΡΡ
Π΄ΠΎΡΡΠΎΠ²Π΅ΡΠ½ΠΎ ΡΠ°ΡΠ΅ Π²ΡΡΡΠ΅ΡΠ°Π»ΠΈΡΡ Π°ΠΊΡΡΡΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΡΠ΅Π½ΠΈ (Ρ < 0,05). ΠΡΠΈ ΠΎΡΠ΅Π½ΠΊΠ΅ ΡΠ»ΡΡΡΠ°Π·Π²ΡΠΊΠΎΠ²ΠΎΠ³ΠΎ ΡΡΡΠΎΠ΅Π½ΠΈΡ ΠΎΠΏΡΡ
ΠΎΠ»ΠΈ ΡΠ»Π΅Π΄ΡΠ΅Ρ ΠΎΠ±ΡΠ°ΡΠΈΡΡ Π²Π½ΠΈΠΌΠ°Π½ΠΈΠ΅ Π½Π° ΡΠ΅Π½Π΄Π΅Π½ΡΠΈΠΈ, Π±ΠΎΠ»Π΅Π΅ Ρ
Π°ΡΠ°ΠΊΡΠ΅ΡΠ½ΡΠ΅ Π΄Π»Ρ Π·Π»ΠΎΠΊΠ°ΡΠ΅ΡΡΠ²Π΅Π½Π½ΡΡ
ΠΎΠΏΡΡ
ΠΎΠ»Π΅ΠΉ, ΠΊ ΠΊΠΎΡΠΎΡΡΠΌ Π½Π΅ΠΎΠ±Ρ
ΠΎΠ΄ΠΈΠΌΠΎ ΠΎΡΠ½Π΅ΡΡΠΈ ΡΠΎΠ»ΠΈΠ΄Π½ΠΎΠ΅ ΡΡΡΠΎΠ΅Π½ΠΈΠ΅ (Ρ = 0,13) ΠΈ Π²ΠΎΠ·Π½ΠΈΠΊΠ½ΠΎΠ²Π΅Π½ΠΈΠ΅ Π°ΡΡΠΈΡΠ° (Ρ = 0,13), Π² ΡΠΎ Π²ΡΠ΅ΠΌΡ ΠΊΠ°ΠΊ ΠΌΠ½ΠΎΠ³ΠΎΠΊΠ°ΠΌΠ΅ΡΠ½ΠΎΡΡΡ Π±Π΅Π· ΡΠΎΠ»ΠΈΠ΄Π½ΠΎΠ³ΠΎ ΠΊΠΎΠΌΠΏΠΎΠ½Π΅Π½ΡΠ° ΡΠ°ΡΠ΅ Π²ΡΡΡΠ΅ΡΠ°Π»Π°ΡΡ Π² Π΄ΠΎΠ±ΡΠΎΠΊΠ°ΡΠ΅ΡΡΠ²Π΅Π½Π½ΡΡ
(Ρ = 0,10). Π Π°Π·ΠΌΠ΅ΡΡ Π½ΠΎΠ²ΠΎΠΎΠ±ΡΠ°Π·ΠΎΠ²Π°Π½ΠΈΡ, Π½Π΅ΡΠΎΠ²Π½ΡΠΉ ΠΊΠΎΠ½ΡΡΡ, ΠΏΠ°ΠΏΠΈΠ»Π»ΡΡΠ½ΡΠ΅ ΡΠ°Π·ΡΠ°ΡΡΠ°Π½ΠΈΡ, Π³ΠΈΠΏΠ΅ΡΡΡ
ΠΎΠ³Π΅Π½Π½ΡΠ΅ Π²ΠΊΠ»ΡΡΠ΅Π½ΠΈΡ ΠΈ Ρ
Π°ΡΠ°ΠΊΡΠ΅Ρ Π²Π½ΡΡΡΠ΅Π½Π½Π΅Π³ΠΎ ΡΠΎΠ΄Π΅ΡΠΆΠΈΠΌΠΎΠ³ΠΎ ΠΊΠΈΡΡΠΎΠ·Π½ΡΡ
ΠΏΠΎΠ»ΠΎΡΡΠ΅ΠΉ ΠΎΠ±Π½Π°ΡΡΠΆΠΈΠ²Π°ΡΡΡΡ ΠΏΡΠΈΠΌΠ΅ΡΠ½ΠΎ Ρ ΠΎΠ΄ΠΈΠ½Π°ΠΊΠΎΠ²ΠΎΠΉ ΡΠ°ΡΡΠΎΡΠΎΠΉ Π² ΠΎΠ±Π΅ΠΈΡ
Π³ΡΡΠΏΠΏΠ°Ρ
. ΠΡΠΈ ΠΎΡΠ΅Π½ΠΊΠ΅ ΠΊΡΠΎΠ²ΠΎΡΠ½Π°Π±ΠΆΠ΅Π½ΠΈΡ ΠΏΠ°ΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΠΎΠ±ΡΠ°Π·ΠΎΠ²Π°Π½ΠΈΡ Π³ΠΈΠΏΠ΅ΡΠ²Π°ΡΠΊΡΠ»ΡΡΠΈΠ·Π°ΡΠΈΡ ΠΌΠΎΠΆΠ΅Ρ ΡΠΊΠ°Π·ΡΠ²Π°ΡΡ Π½Π° Π·Π»ΠΎΠΊΠ°ΡΠ΅ΡΡΠ²Π΅Π½Π½ΡΡ ΠΏΡΠΈΡΠΎΠ΄Ρ ΠΎΠΏΡΡ
ΠΎΠ»ΠΈ (Ρ < 0,05), Π²ΠΌΠ΅ΡΡΠ΅ Ρ ΡΠ΅ΠΌ Π°Π²Π°ΡΠΊΡΠ»ΡΡΠΈΠ·Π°ΡΠΈΡ ΡΠ°ΠΊΠΆΠ΅ Π±ΡΠ»Π° ΠΎΡΠΌΠ΅ΡΠ΅Π½Π° Π² ΠΏΠΎΠ΄ΠΎΠ±Π½ΡΡ
Π½ΠΎΠ²ΠΎΠΎΠ±ΡΠ°Π·ΠΎΠ²Π°Π½ΠΈΡΡ
, ΠΏΡΠΈ ΡΡΠΎΠΌ ΡΠ°Π·Π»ΠΈΡΠΈΡ Ρ Π΄ΠΎΠ±ΡΠΎΠΊΠ°ΡΠ΅ΡΡΠ²Π΅Π½Π½ΡΠΌΠΈ Π±ΡΠ»ΠΈ Π½Π΅Π΄ΠΎΡΡΠΎΠ²Π΅ΡΠ½ΡΠΌΠΈ (p = 0,06).ΠΠ°ΠΊΠ»ΡΡΠ΅Π½ΠΈΠ΅. ΠΠΎΡΡΠΎΠ²Π΅ΡΠ½ΡΠ΅ ΡΡ
ΠΎΠ³ΡΠ°ΡΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΠΏΡΠΈΠ·Π½Π°ΠΊΠΈ, ΠΎΠΏΡΠ΅Π΄Π΅Π»ΡΡΡΠΈΠ΅ ΠΎΡΠΎΠ±Π΅Π½Π½ΠΎΡΡΠΈ ΠΌΠΎΡΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΡΠΈΠΏΠ° Π½ΠΎΠ²ΠΎ ΠΎΠ±ΡΠ°Π·ΠΎΠ²Π°Π½ΠΈΡ, ΠΎΡΡΡΡΡΡΠ²ΡΡΡ. Π‘ΠΎΠ²ΠΎΠΊΡΠΏΠ½ΠΎΡΡΡ ΠΊΡΠΈΡΠ΅ΡΠΈΠ΅Π² ΠΏΠΎΠ·Π²ΠΎΠ»ΠΈΡ ΠΏΠΎΠ²ΡΡΠΈΡΡ ΠΊΠ°ΡΠ΅ΡΡΠ²ΠΎ Π΄ΠΎΠΎΠΏΠ΅ΡΠ°ΡΠΈΠΎΠ½Π½ΠΎΠΉ ΡΠ»ΡΡΡΠ°Π·Π²ΡΠΊΠΎΠ²ΠΎΠΉ Π΄ΠΈΠ°Π³Π½ΠΎΡΡΠΈΠΊΠΈ ΠΎΠΏΡΡ
ΠΎΠ»Π΅ΠΉ ΡΠΈΡΠ½ΠΈΠΊΠΎΠ²
Π£Π»ΡΡΡΠ°Π·Π²ΡΠΊΠΎΠ²ΡΠ΅ ΠΏΡΠΈΠ·Π½Π°ΠΊΠΈ ΠΎΠΏΡΡ ΠΎΠ»Π΅ΠΉ ΡΠΈΡΠ½ΠΈΠΊΠΎΠ² ΠΏΠΎ ΡΡΠ°Π½Π΄Π°ΡΡΠΈΠ·ΠΎΠ²Π°Π½Π½ΠΎΠΌΡ ΠΏΡΠΎΡΠΎΠΊΠΎΠ»Ρ
Objective: to identify the characteristic echographic features of benign ovarian tumors using the recommendations of the IOTA group.Materials and methods. Five articles published in the journal Ultrasound in Obstetrics & Gynecology for 2008β2019 were analyzed. Each article is devoted to a histologically verified pathology of the ovaries, representing four morphological variants of an ovarian tumor (strum, fibroma/fibrothecoma, uroepithelial tumor (Brenner's tumor) and cystadenofibroma, as well as endometrioma in pregnancy. The total number was 380 women. When describing pathological formations, the researchers used a single protocol recommended by the IOTA group. Evaluated twentyone parameters, including the morphology of the formation, the structure of fluid inclusions and the solid component, the presence of fluid in the retrouterine space and ascites, as well as the degree of tumor vascularization.Results. The analysis of the struma, fibroma (fibrothecoma), Brenner tumor, cystadenofibroma and endometrioma of pregnant women indicates that there are no reliable criteria for diagnosing the histological structure of the tumor, both by the age of the patients, the size of the formation, and by ultrasound signs. Hyperechoic inclusions, which are noted only in Brenner tumors, both benign and malignant, can serve as the only marker among the pathology under consideration. In the study of the listed benign neoplasms of the ovaries, no features of the blood supply were revealed. All neoplasms had vascularization from the complete absence of vessels (1 point) to their moderate number (3 points). Hypervascularization (4 points) occurred in struma, fibroma (fibrotecoma), and cystadenofibroma.Conclusions. The task of ultrasound examination is the timely detection of an ovarian tumor with a presumptive conclusion of the probability of malignancy, based on standardized protocols of the IOTA group, which is important for the correct routing of the patient.Β Π¦Π΅Π»Ρ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ: Π²ΡΡΠ²ΠΈΡΡ Ρ
Π°ΡΠ°ΠΊΡΠ΅ΡΠ½ΡΠ΅ ΡΡ
ΠΎΠ³ΡΠ°ΡΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΠΏΡΠΈΠ·Π½Π°ΠΊΠΈ Π΄ΠΎΠ±ΡΠΎΠΊΠ°ΡΠ΅ΡΡΠ²Π΅Π½Π½ΡΡ
ΠΎΠΏΡΡ
ΠΎΠ»Π΅ΠΉ ΡΠΈΡΠ½ΠΈΠΊΠΎΠ² Ρ ΠΏΡΠΈΠΌΠ΅Π½Π΅Π½ΠΈΠ΅ΠΌ ΡΠ΅ΠΊΠΎΠΌΠ΅Π½Π΄Π°ΡΠΈΠΉ Π³ΡΡΠΏΠΏΡ IOTA.ΠΠ°ΡΠ΅ΡΠΈΠ°Π» ΠΈ ΠΌΠ΅ΡΠΎΠ΄Ρ. ΠΡΠΎΠ°Π½Π°Π»ΠΈΠ·ΠΈΡΠΎΠ²Π°Π½Ρ 5 ΡΡΠ°ΡΠ΅ΠΉ, ΠΎΠΏΡΠ±Π»ΠΈΠΊΠΎΠ²Π°Π½Π½ΡΡ
Π² ΠΆΡΡΠ½Π°Π»Π΅ Ultrasound in Obstetrics & Gynecology Π·Π° 2008β2019 Π³Π³. ΠΠ°ΠΆΠ΄Π°Ρ ΡΡΠ°ΡΡΡ ΠΏΠΎΡΠ²ΡΡΠ΅Π½Π° Π³ΠΈΡΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈ Π²Π΅ΡΠΈΡΠΈΡΠΈΡΠΎΠ²Π°Π½Π½ΠΎΠΉ ΠΏΠ°ΡΠΎΠ»ΠΎΠ³ΠΈΠΈ ΡΠΈΡΠ½ΠΈΠΊΠΎΠ², ΠΏΡΠ΅Π΄ΡΡΠ°Π²Π»ΡΡΡΠΈΡ
4 ΠΌΠΎΡΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ
Π²Π°ΡΠΈΠ°Π½ΡΠ° ΠΎΠΏΡΡ
ΠΎΠ»ΠΈ ΡΠΈΡΠ½ΠΈΠΊΠΎΠ²: ΡΡΡΡΠΌΠ°, ΡΠΈΠ±ΡΠΎΠΌΠ°/ΡΠΈΠ±ΡΠΎΡΠ΅ΠΊΠΎΠΌΠ°, ΡΡΠΎΡΠΏΠΈΡΠ΅Π»ΠΈΠ°Π»ΡΠ½Π°Ρ ΠΎΠΏΡΡ
ΠΎΠ»Ρ (ΠΎΠΏΡΡ
ΠΎΠ»Ρ ΠΡΠ΅Π½Π½Π΅ΡΠ°) ΠΈ ΡΠΈΡΡΠ°Π΄Π΅Π½ΠΎΡΠΈΠ±ΡΠΎΠΌΠ°, Π° ΡΠ°ΠΊΠΆΠ΅ ΡΠ½Π΄ΠΎΠΌΠ΅ΡΡΠΈΠΎΠΈΠ΄Π½Π°Ρ ΠΊΠΈΡΡΠ° ΠΏΡΠΈ Π±Π΅ΡΠ΅ΠΌΠ΅Π½Π½ΠΎΡΡΠΈ. ΠΠ±ΡΠ΅Π΅ ΠΊΠΎΠ»ΠΈΡΠ΅ΡΡΠ²ΠΎ ΡΠΎΡΡΠ°Π²ΠΈΠ»ΠΎ 380 ΠΆΠ΅Π½ΡΠΈΠ½. ΠΡΠΈ ΠΎΠΏΠΈΡΠ°Π½ΠΈΠΈ ΠΏΠ°ΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ
ΠΎΠ±ΡΠ°Π·ΠΎΠ²Π°Π½ΠΈΠΉ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°ΡΠ΅Π»ΠΈ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π»ΠΈ Π΅Π΄ΠΈΠ½ΡΠΉ ΠΏΡΠΎΡΠΎΠΊΠΎΠ», ΡΠ΅ΠΊΠΎΠΌΠ΅Π½Π΄ΠΎΠ²Π°Π½Π½ΡΠΉ Π³ΡΡΠΏΠΏΠΎΠΉ IOTA. ΠΡΠ΅Π½ΠΈΠ²Π°Π»ΡΡ 21 ΠΏΠ°ΡΠ°ΠΌΠ΅ΡΡ, Π²ΠΊΠ»ΡΡΠ°ΡΡΠΈΠΉ ΠΌΠΎΡΡΠΎΠ»ΠΎΠ³ΠΈΡ ΠΎΠ±ΡΠ°Π·ΠΎΠ²Π°Π½ΠΈΡ, ΡΡΡΡΠΊΡΡΡΡ ΠΆΠΈΠ΄ΠΊΠΎΡΡΠ½ΡΡ
Π²ΠΊΠ»ΡΡΠ΅Π½ΠΈΠΉ ΠΈ ΡΠΎΠ»ΠΈΠ΄Π½ΠΎΠ³ΠΎ ΠΊΠΎΠΌΠΏΠΎΠ½Π΅Π½ΡΠ°, Π½Π°Π»ΠΈΡΠΈΠ΅ ΠΆΠΈΠ΄ΠΊΠΎΡΡΠΈ Π² ΠΏΠΎΠ·Π°Π΄ΠΈΠΌΠ°ΡΠΎΡΠ½ΠΎΠΌ ΠΏΡΠΎΡΡΡΠ°Π½ΡΡΠ²Π΅ ΠΈ Π°ΡΡΠΈΡ, Π° ΡΠ°ΠΊΠΆΠ΅ ΡΡΠ΅ΠΏΠ΅Π½Ρ Π²Π°ΡΠΊΡΠ»ΡΡΠΈΠ·Π°ΡΠΈΠΈ ΠΎΠΏΡΡ
ΠΎΠ»ΠΈ.Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ. ΠΡΠΎΠ²Π΅Π΄Π΅Π½Π½ΡΠΉ Π°Π½Π°Π»ΠΈΠ· ΡΡΡΡΠΌΡ, ΡΠΈΠ±ΡΠΎΠΌΡ (ΡΠΈΠ±ΡΠΎΡΠ΅ΠΊΠΎΠΌΡ), ΠΎΠΏΡΡ
ΠΎΠ»ΠΈ ΠΡΠ΅Π½Π½Π΅ΡΠ°, ΡΠΈΡΡΠ°Π΄Π΅Π½ΠΎΡΠΈΠ±ΡΠΎΠΌΡ ΠΈ ΡΠ½Π΄ΠΎΠΌΠ΅ΡΡΠΈΠΎΠΈΠ΄Π½ΠΎΠΉ ΠΊΠΈΡΡΡ Π±Π΅ΡΠ΅ΠΌΠ΅Π½Π½ΡΡ
ΡΠ²ΠΈΠ΄Π΅ΡΠ΅Π»ΡΡΡΠ²ΡΠ΅Ρ ΠΎ ΡΠΎΠΌ, ΡΡΠΎ ΠΎΡΡΡΡΡΡΠ²ΡΡΡ Π½Π°Π΄Π΅ΠΆΠ½ΡΠ΅ ΠΊΡΠΈΡΠ΅ΡΠΈΠΈ Π΄ΠΈΠ°Π³Π½ΠΎΡΡΠΈΠΊΠΈ Π³ΠΈΡΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΡΡΡΠΎΠ΅Π½ΠΈΡ ΠΎΠΏΡΡ
ΠΎΠ»ΠΈ ΠΊΠ°ΠΊ ΠΏΠΎ Π²ΠΎΠ·ΡΠ°ΡΡΡ Π±ΠΎΠ»ΡΠ½ΡΡ
, ΡΠ°Π·ΠΌΠ΅ΡΠ°ΠΌ ΠΎΠ±ΡΠ°Π·ΠΎΠ²Π°Π½ΠΈΡ, ΡΠ°ΠΊ ΠΈ ΠΏΠΎ ΡΠ»ΡΡΡΠ°Π·Π²ΡΠΊΠΎΠ²ΡΠΌ ΠΏΡΠΈΠ·Π½Π°ΠΊΠ°ΠΌ. ΠΠ΄ΠΈΠ½ΡΡΠ²Π΅Π½Π½ΡΠΌ ΠΌΠ°ΡΠΊΠ΅ΡΠΎΠΌ ΡΡΠ΅Π΄ΠΈ ΡΠ°ΡΡΠΌΠ°ΡΡΠΈΠ²Π°Π΅ΠΌΠΎΠΉ ΠΏΠ°ΡΠΎΠ»ΠΎΠ³ΠΈΠΈ ΠΌΠΎΠ³ΡΡ ΡΠ»ΡΠΆΠΈΡΡ Π³ΠΈΠΏΠ΅ΡΡΡ
ΠΎΠ³Π΅Π½Π½ΡΠ΅ Π²ΠΊΠ»ΡΡΠ΅Π½ΠΈΡ, ΠΊΠΎΡΠΎΡΡΠ΅ ΠΎΡΠΌΠ΅ΡΠ΅Π½Ρ ΡΠΎΠ»ΡΠΊΠΎ Π² ΠΎΠΏΡΡ
ΠΎΠ»ΡΡ
ΠΡΠ΅Π½Π½Π΅ΡΠ°, ΠΊΠ°ΠΊ Π΄ΠΎΠ±ΡΠΎΠΊΠ°ΡΠ΅ΡΡΠ²Π΅Π½Π½ΡΡ
, ΡΠ°ΠΊ ΠΈ Π·Π»ΠΎΠΊΠ°ΡΠ΅ΡΡΠ²Π΅Π½Π½ΡΡ
. ΠΡΠΈ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠΈ ΠΏΠ΅ΡΠ΅ΡΠΈΡΠ»Π΅Π½Π½ΡΡ
Π΄ΠΎΠ±ΡΠΎΠΊΠ°ΡΠ΅ΡΡΠ²Π΅Π½Π½ΡΡ
Π½ΠΎΠ²ΠΎΠΎΠ±ΡΠ°Π·ΠΎΠ²Π°Π½ΠΈΠΉ ΡΠΈΡΠ½ΠΈΠΊΠΎΠ² Π½Π΅ Π²ΡΡΠ²Π»Π΅Π½ΠΎ ΠΎΡΠΎΠ±Π΅Π½Π½ΠΎΡΡΠ΅ΠΉ ΠΊΡΠΎΠ²ΠΎΡΠ½Π°Π±ΠΆΠ΅Π½ΠΈΡ. ΠΡΠ΅ Π½ΠΎΠ²ΠΎΠΎΠ±ΡΠ°Π·ΠΎΠ²Π°Π½ΠΈΡ ΠΈΠΌΠ΅Π»ΠΈ Π²Π°ΡΠΊΡΠ»ΡΡΠΈΠ·Π°ΡΠΈΡ ΠΎΡ ΠΏΠΎΠ»Π½ΠΎΠ³ΠΎ ΠΎΡΡΡΡΡΡΠ²ΠΈΡ ΡΠΎΡΡΠ΄ΠΎΠ² (1 Π±Π°Π»Π») Π΄ΠΎ ΡΠΌΠ΅ΡΠ΅Π½Π½ΠΎΠ³ΠΎ ΠΈΡ
ΠΊΠΎΠ»ΠΈΡΠ΅ΡΡΠ²Π° (3 Π±Π°Π»Π»Π°). ΠΠΈΠΏΠ΅ΡΠ²Π°ΡΠΊΡΠ»ΡΡΠΈΠ·Π°ΡΠΈΡ (4 Π±Π°Π»Π»Π°) Π²ΡΡΡΠ΅ΡΠ°Π»Π°ΡΡ Π² ΡΡΡΡΠΌΠ΅, ΡΠΈΠ±ΡΠΎΠΌΠ΅ (ΡΠΈΠ±ΡΠΎΡΠ΅ΠΊΠΎΠΌΠ΅) ΠΈ ΡΠΈΡΡΠ°Π΄Π΅Π½ΠΎΡΠΈΠ±ΡΠΎΠΌΠ΅.ΠΠ°ΠΊΠ»ΡΡΠ΅Π½ΠΈΠ΅. ΠΠ°Π΄Π°ΡΠ΅ΠΉ ΡΠ»ΡΡΡΠ°Π·Π²ΡΠΊΠΎΠ²ΠΎΠ³ΠΎ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ ΡΠ²Π»ΡΠ΅ΡΡΡ ΡΠ²ΠΎΠ΅Π²ΡΠ΅ΠΌΠ΅Π½Π½ΠΎΠ΅ Π²ΡΡΠ²Π»Π΅Π½ΠΈΠ΅ ΠΎΠΏΡΡ
ΠΎΠ»ΠΈ ΡΠΈΡΠ½ΠΈΠΊΠ° Ρ ΠΏΡΠ΅Π΄ΠΏΠΎΠ»ΠΎΠΆΠΈΡΠ΅Π»ΡΠ½ΡΠΌ Π·Π°ΠΊΠ»ΡΡΠ΅Π½ΠΈΠ΅ΠΌ Π²Π΅ΡΠΎΡΡΠ½ΠΎΡΡΠΈ ΠΌΠ°Π»ΠΈΠ³Π½ΠΈΠ·Π°ΡΠΈΠΈ, ΠΎΡΠ½ΠΎΠ²Π°Π½Π½ΠΎΠΌ Π½Π° ΡΡΠ°Π½Π΄Π°ΡΡΠΈΠ·ΠΎΠ²Π°Π½Π½ΡΡ
ΠΏΡΠΎΡΠΎΠΊΠΎΠ»Π°Ρ
Π³ΡΡΠΏΠΏΡ IOTA, ΡΡΠΎ Π²Π°ΠΆΠ½ΠΎ Π΄Π»Ρ ΠΏΡΠ°Π²ΠΈΠ»ΡΠ½ΠΎΠΉ ΠΌΠ°ΡΡΡΡΡΠΈΠ·Π°ΡΠΈΠΈ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΊΠΈ
ΠΠΠ«Π’ Π£ΠΠ¬Π’Π ΠΠΠΠ£ΠΠΠΠΠΠ ΠΠ‘Π‘ΠΠΠΠΠΠΠΠΠ― Π‘ ΠΠΠΠ’Π ΠΠ‘Π’ΠΠ«Π Π£Π‘ΠΠΠΠΠΠΠ ΠΠ Π ΠΠΠΠΠΠΠ‘Π’ΠΠΠ Π ΠΠΠ Π¨ΠΠΠΠ ΠΠΠ’ΠΠ
The purpose of the study was to evaluate the value of contrast-enhanced ultrasound in detecting local spread, regional and distant metastases from cervical cancer. Materials and methods. The findings of contrast-enhanced ultrasound examination of 4 cervical cancer patients (IB1βIVB) treated at N.N. Blokhin Russian Cancer Research Center from September to October 2016 were evaluated. The HI VISION Ascendus device was used. Ultrasound patterns in different phases of contrast-enhanced accumulation and excretion were analyzed. Results. Our first experience in using contrast-enhanced ultrasound in the detection of local spread, regional and distant metastases from cervical cancer allowed us to study the structure of the tumor and its spread in greater detail. Conclusion. A small number of observations do not yet allow us to draw serious conclusions about the capabilities of this modern technology.Β Π¦Π΅Π»Ρ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ. ΠΡΠ΅Π½ΠΈΡΡ Π²ΠΎΠ·ΠΌΠΎΠΆΠ½ΠΎΡΡΠΈ ΠΊΠΎΠ½ΡΡΠ°ΡΡΠ½ΠΎ-ΡΡΠΈΠ»Π΅Π½Π½ΠΎΠ³ΠΎ ΡΠ»ΡΡΡΠ°Π·Π²ΡΠΊΠΎΠ²ΠΎΠ³ΠΎ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ (ΠΠ£Π£ΠΠ) Π² Π΄ΠΈΠ°Π³Π½ΠΎΡΡΠΈΠΊΠ΅ ΠΌΠ΅ΡΡΠ½ΠΎΠ³ΠΎ ΡΠ°ΡΠΏΡΠΎΡΡΡΠ°Π½Π΅Π½ΠΈΡ, ΡΠ΅Π³ΠΈΠΎΠ½Π°ΡΠ½ΡΡ
ΠΈ ΠΎΡΠ΄Π°Π»Π΅Π½Π½ΡΡ
ΠΌΠ΅ΡΠ°ΡΡΠ°Π·ΠΎΠ² ΡΠ°ΠΊΠ° ΡΠ΅ΠΉΠΊΠΈ ΠΌΠ°ΡΠΊΠΈ (Π Π¨Π). ΠΠ°ΡΠ΅ΡΠΈΠ°Π» ΠΈ ΠΌΠ΅ΡΠΎΠ΄Ρ. ΠΡΠΎΠ°Π½Π°Π»ΠΈΠ·ΠΈΡΠΎΠ²Π°Π½Ρ ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΡ ΠΠ£Π£ΠΠ ΡΠ΅ΡΡΡΠ΅Ρ
ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠΊ Ρ Π΄ΠΈΠ°Π³Π½ΠΎΠ·ΠΎΠΌ Π Π¨Π IB1βIVB ΡΡΠ°Π΄ΠΈΠΉ, Π½Π°Ρ
ΠΎΠ΄ΠΈΠ²ΡΠΈΡ
ΡΡ Π½Π° ΠΎΠ±ΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠΈ ΠΈ ΡΡΠ°ΡΠΈΠΎΠ½Π°ΡΠ½ΠΎΠΌ Π»Π΅ΡΠ΅Π½ΠΈΠΈ Π² Π ΠΠΠ¦ ΠΈΠΌ Π.Π.ΠΠ»ΠΎΡ
ΠΈΠ½Π° Π² ΠΏΠ΅ΡΠΈΠΎΠ΄ Ρ ΡΠ΅Π½ΡΡΠ±ΡΡ ΠΏΠΎ ΠΎΠΊΡΡΠ±ΡΡ 2016 Π³ΠΎΠ΄Π°. Π£Π»ΡΡΡΠ°Π·Π²ΡΠΊΠΎΠ²ΠΎΠ΅ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠ΅ ΠΏΡΠΎΠ²ΠΎΠ΄ΠΈΠ»ΠΈ Π½Π° Π°ΠΏΠΏΠ°ΡΠ°ΡΠ΅ Β«Hitachi Hi Vision AscendusΒ», ΡΠ°ΡΡΠΌΠΎΡΡΠ΅Π½Ρ ΠΎΡΠΎΠ±Π΅Π½Π½ΠΎΡΡΠΈ ΡΠ»ΡΡΡΠ°Π·Π²ΡΠΊΠΎΠ²ΠΎΠΉ ΠΊΠ°ΡΡΠΈΠ½Ρ Π² ΡΠ°Π·Π½ΡΠ΅ ΡΠ°Π·Ρ Π½Π°ΠΊΠΎΠΏΠ»Π΅Π½ΠΈΡ ΠΈ Π²ΡΠ²Π΅Π΄Π΅Π½ΠΈΡ ΠΊΠΎΠ½ΡΡΠ°ΡΡΠ½ΠΎΠ³ΠΎ ΠΏΡΠ΅ΠΏΠ°ΡΠ°ΡΠ° Π‘ΠΎΠ½ΠΎΠ²ΡΡ. Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ. ΠΠ΅ΡΠ²ΡΠΉ ΠΎΠΏΡΡ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½ΠΈΡ ΠΊΠΎΠ½ΡΡΠ°ΡΡΠ½ΠΎΠ³ΠΎ ΡΡΠΈΠ»Π΅Π½ΠΈΡ (ΠΠ£) ΠΏΡΠΈ ΡΠ»ΡΡΡΠ°Π·Π²ΡΠΊΠΎΠ²ΠΎΠΌ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠΈ (Π£ΠΠ) Π² Π΄ΠΈΠ°Π³Π½ΠΎΡΡΠΈΠΊΠ΅ ΠΌΠ΅ΡΡΠ½ΠΎΠ³ΠΎ ΡΠ°ΡΠΏΡΠΎΡΡΡΠ°Π½Π΅Π½ΠΈΡ, ΡΠ΅Π³ΠΈΠΎΠ½Π°ΡΠ½ΡΡ
ΠΈ ΠΎΡΠ΄Π°Π»Π΅Π½Π½ΡΡ
ΠΌΠ΅ΡΠ°ΡΡΠ°Π·ΠΎΠ² Π Π¨Π ΠΏΠΎΠ·Π²ΠΎΠ»ΠΈΠ» Π±ΠΎΠ»Π΅Π΅ Π΄Π΅ΡΠ°Π»ΡΠ½ΠΎ ΠΈΠ·ΡΡΠΈΡΡ ΡΡΡΡΠΊΡΡΡΡ ΠΎΠΏΡΡ
ΠΎΠ»ΠΈ ΠΈ Ρ
Π°ΡΠ°ΠΊΡΠ΅Ρ Π΅Π΅ ΡΠ°ΡΠΏΡΠΎΡΡΡΠ°Π½Π΅Π½ΠΈΡ. ΠΠ°ΠΊΠ»ΡΡΠ΅Π½ΠΈΠ΅. ΠΠ΅Π±ΠΎΠ»ΡΡΠΎΠ΅ ΠΊΠΎΠ»ΠΈΡΠ΅ΡΡΠ²ΠΎ Π½Π°Π±Π»ΡΠ΄Π΅Π½ΠΈΠΉ Π½Π΅ ΠΏΠΎΠ·Π²ΠΎΠ»ΡΠ΅Ρ ΠΏΠΎΠΊΠ° ΡΠ΄Π΅Π»Π°ΡΡ ΡΠ΅ΡΡΠ΅Π·Π½ΡΡ
Π²ΡΠ²ΠΎΠ΄ΠΎΠ² ΠΎ Π²ΠΎΠ·ΠΌΠΎΠΆΠ½ΠΎΡΡΡΡ
ΡΡΠΎΠΉ ΡΠΎΠ²ΡΠ΅ΠΌΠ΅Π½Π½ΠΎΠΉ ΡΠ΅Ρ
Π½ΠΎΠ»ΠΎΠ³ΠΈΠΈ.
Optimization of therapy of corneal conjunctival xerosis and evaluation of pharmacoeconomic efficiency
In this study, the analysis of transient corneal-conjunctival xerosis (CCX) therapy, clinical manifestations and indices of local immune resistance and lacrimal gland function were included in the inclusion of pro-activ and actipol in CCX complex therapy. It was found that this scheme increases the function of tear formation and favorably affects local immune defense (the factor of nonΒspecific immune resistance and the pro-inflammatory cytokine IL-1 b) in this category of patients. With the pharmacoeconomic analysis performed, taking into account the frequency of recurrence and the duration of remission, greater efficacy was shown in the use of immunomodulatory therapy.Π Π΄Π°Π½Π½ΠΎΠΌ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠΈ ΠΏΡΠΎΠΈΠ·Π²Π΅Π΄Π΅Π½ Π°Π½Π°Π»ΠΈΠ· ΡΠ΅ΡΠ°ΠΏΠΈΠΈ ΡΡΠ°Π½Π·ΠΈΡΠΎΡΠ½ΠΎΠ³ΠΎ ΡΠΎΠ³ΠΎΠ²ΠΈΡΠ½ΠΎ-ΠΊΠΎΠ½ΡΡΠ½ΠΊΡΠΈΠ²Π°Π»ΡΠ½ΠΎΠ³ΠΎ ΠΊΡΠ΅ΡΠΎΠ·Π° (Π ΠΠ), ΠΊΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΠΏΡΠΎΡΠ²Π»Π΅Π½ΠΈΡ ΠΈ ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»ΠΈ ΠΌΠ΅ΡΡΠ½ΠΎΠΉ ΠΈΠΌΠΌΡΠ½Π½ΠΎΠΉ ΡΠ΅Π·ΠΈΡΡΠ΅Π½ΡΠ½ΠΎΡΡΠΈ ΠΈ ΡΡΠ½ΠΊΡΠΈΠΈ ΡΠ»Π΅Π·Π½ΡΡ
ΠΆΠ΅Π»Π΅Π· ΠΏΡΠΈ Π²ΠΊΠ»ΡΡΠ΅Π½ΠΈΠΈ Β«ΠΡΠΎ-Π°ΠΊΡΠΈΠ²Π°Β» ΠΈ Π°ΠΊΡΠΈΠΏΠΎΠ»Π° Π² ΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡΠ½ΡΡ ΡΠ΅ΡΠ°ΠΏΠΈΡ Π ΠΠ. ΠΡΡΠ²Π»Π΅Π½ΠΎ, ΡΡΠΎ ΡΠΊΠ°Π·Π°Π½Π½Π°Ρ ΡΡ
Π΅ΠΌΠ° ΠΏΠΎΠ²ΡΡΠ°Π΅Ρ ΡΡΠ½ΠΊΡΠΈΡ ΡΠ»Π΅Π·ΠΎΠΎΠ±ΡΠ°Π·ΠΎΠ²Π°Π½ΠΈΡ ΠΈ Π±Π»Π°Π³ΠΎΠΏΡΠΈΡΡΠ½ΠΎ Π²Π»ΠΈΡΠ΅Ρ Π½Π° ΠΌΠ΅ΡΡΠ½ΡΡ ΠΈΠΌΠΌΡΠ½Π½ΡΡ Π·Π°ΡΠΈΡΡ (ΡΠ°ΠΊΡΠΎΡ Π½Π΅ΡΠΏΠ΅ΡΠΈΡΠΈΡΠ΅ΡΠΊΠΎΠΉ ΠΈΠΌΠΌΡΠ½Π½ΠΎΠΉ ΡΠ΅Π·ΠΈΡΡΠ΅Π½ΡΠ½ΠΎΡΡΠΈ ΠΈ ΠΏΡΠΎΠ²ΠΎΡΠΏΠ°Π»ΠΈΡΠ΅Π»ΡΠ½ΡΠΉ ΡΠΈΡΠΎΠΊΠΈΠ½ IL-1b) Ρ Π΄Π°Π½Π½ΠΎΠΉ ΠΊΠ°ΡΠ΅Π³ΠΎΡΠΈΠΈ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ². ΠΡΠΈ ΠΏΡΠΎΠΈΠ·Π²Π΅Π΄Π΅Π½Π½ΠΎΠΌ ΡΠ°ΡΠΌΠ°ΠΊΠΎΠ·ΠΊΠΎΠ½ΠΎΠΌΠΈΡΠ΅ΡΠΊΠΎΠΌ Π°Π½Π°Π»ΠΈΠ·Π΅ Ρ ΡΡΠ΅ΡΠΎΠΌ ΡΠ°ΡΡΠΎΡΡ ΡΠ΅ΡΠΈΠ΄ΠΈΠ²ΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΠΈ ΠΏΡΠΎΠ΄ΠΎΠ»ΠΆΠΈΡΠ΅Π»ΡΠ½ΠΎΡΡΠΈ ΡΠ΅ΠΌΠΈΡΡΠΈΠΈ Π²ΡΡΠ²Π»Π΅Π½Π° Π±ΠΎΠ»ΡΡΠ°Ρ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ ΠΏΡΠΈ ΠΏΡΠΈΠΌΠ΅Π½Π΅Π½ΠΈΠΈ ΠΈΠΌΠΌΡΠ½ΠΎΠΌΠΎΠ΄ΡΠ»ΠΈΡΡΡΡΠ΅ΠΉ ΡΠ΅ΡΠ°ΠΏΠΈΠΈ
Contrast-enhanced ultrasound and tissue elastography in the differential diagnosis of primary and metastatic ovarian tumors in uterine cancer patients: our experience
Objective: to study the possibilities of tissue elastography and contrast-enhanced ultrasound in the differential diagnosis of primary and metastatic ovarian tumors in uterine cancer patients.Materials and methods. The results of observations of 8 patients were analyzed.Results. We identified 8 patients with ovarian tumors, of whom 4 had synchronous primary cancers of the endometrium (synchronous group) and ovary and 4 had endometrial cancer with ovarian metastasis (metastasis group). Ovarian tumors in the synchronous group were more often unilateral, the structure of the ovarian tumor is more often multilocular-solid with uneven, clear contours, the size of the ovaries exceeds 6 cm, and the ovaries were mapped with 4 types of elastograms during tissue elastography. In this group dissemination of the process was not detected. Ovarian tumors in metastasis group were both bilateral and unilateral, represented by solid formations with clear, even contours, ovarian size did not exceed 6 cm, disseminated process was revealed in half of the cases (metastases in the greater omentum and in the retroperitoneal lymph nodes). With tissue elastography solidformations in the structure of the ovaries were mapped mainly by type 5 elastograms. With contrast-enhanced ultrasound in areas of a solid structure a rapid accumulation of the contrast agent in the arterial phase and its rapid excretion into the venous phase was revealed, only the contours of the walls and septum were visualized in the late phase with the multilocularsolid structure of the ovary.Conclusions. When we conduct an ultrasound examination of patients with a uterine cancer, a thorough study of the structure of the ovaries is important for timely diagnosis of the tumor. Further development of differential diagnostic criteria for macrometastases and synchronous ovarian tumors using modern ultrasound technologies is a promising task, since this information is necessary to correct the volume of surgery in this category of patients
Features of ultrasound of endometrial pathological conditions in breast cancer patients receiving tamoxifen: a review of literature
The article examines the possibilities and features of ultrasound in the diagnosis of endometrial pathological conditions on the background of taking tamoxifen in women diagnosed with breast cancer based on data obtained from studying the sources of domestic and foreign literature from 1994 to 2018
Significance of ultrasound morphological comparisons in the complex ultrasound diagnosis of the cervix uteri
Ten ultrasound morphological comparisons were made on the removed uterus for endometrial cancer. The specific features of its ultra- sound image were studied in details. An attempt was undertaken to explain these or those echographic signs when comparing with tumor histotopographic sections
The estimation of functional reserves of organism of children and teenagers health
The unified methodic of level of functional reserves as the basic indicator of children and teenagers health was represented. Age-sexual standards of functional reserves of children and teenagers 5-18 years were determinated. The 5-step algorithm of functional reserves of estimation that provide donosological diagnostics and prophylactic program was established.
Estimation of functional reserves of children and teenagers, screening diagnostics, functional tests, age-sexual standards of functional reserves, donosological diagnostics