Primena Veberovih fokalno-direktrisnih ravanskih krivih u aproksimaciji konturne krive osnove arhitektonskih objekata

One of the major aims when researching some problems in architectural design of buildings is to fully understand and adequately apply the underlying scientific foundations that architects use in their projects. In this paper we analyze the application possibilities of the Weber's focal-directorial curves in the approximation of ground-base contour line of architectural objects i.e. buildings. Thus, a Weber's curve with m foci and n directrices was defined. Furthermore, particular qualifiers were introduced in order to estimate the level of adequacy of the conducted approximation. The importance of the research can be sought in the fact that the exact procedure has been created with its applicability in architectural-urban design of contemporary forms as well as in the domain of the historical heritage and conservation in the sense of the creating proper geometrical models for further computer aided use.Jedan od glavnih ciljeva istraživanja nekih problema u arhitektonskom dizajniranju zgrada je potpuno razumevanje i adekvatno primenjivanje naučnih načela koje arhitekte koriste u svojim projektima. U ovom radu analiziramo mogu nosti primene eberovih fokalno-direktrisnih krivih u aproksimaciji konture osnove arhitektonskih objekata, tj. zgrada. U vezi sa tim, definisana je Veberova kriva sa m fokusa i n direktrisa. Osim toga, uvedeni su posebni kvalifikatori kako bi se procenio nivo preciznosti izvršene aproksimacije. ažnost istraživanja se posebno iskazuje u činjenici da je postupak kreiran sa mogu noš u primene u arhitektonsko-urbanističkom dizajniranju savremenih oblika, kao i u domenu zaštite i revitalizacije istorijskog nasle a u smislu stvaranja odgovaraju ih geometrijskih modela za dalju upotrebu pomo u računara

Exposure assessment to essential elements through the consumption of canned fish in Serbia

The aim of this study was to provide a quantitative exposure assessment to essential elements through the consumption of canned fish in Serbia. This objective was fulfilled by analyzing content of essential elements in canned fish and by using data from a food consumption survey. Consumption survey of canned fish was designed and performed to general principles and EFSA guidelines on data collection of national food consumption. The questionnaire was performed on 1,000 respondents during 2018. Determination of copper, zinc and iron levels were performed on 454 canned fish and seafood samples divided into four groups (canned tuna, canned sardines, canned other sea fish and canned seafood) during five consecutive years (2014–2018). This study showed significant association between sex, BMI and weight and consumption patterns. Obtained average weekly consumption of canned fish confirms our assumption that consumption of canned fish is significant in Serbia. Zinc and iron were found in all 454 samples (100%), and copper in 222 samples (48.9%). The average obtained concentration in all samples were 1.268 mg kg–1 for Cu, 5.661 mg kg–1 for Zn and 9.556 mg kg–1 for Fe. The highest concentration for all three minerals were found in canned sardines (Cu — 6.49 mg kg–1, Zn — 37.2 mg kg–1 and Fe — 21.8 mg kg–1). Obtained mean exposure to intake of copper, zinc and iron from canned fish was 1.2241 μg/kg bw/day, 5.4634 μg/kg bw/day and 9.2231 μg/kg bw/day, respectively. Exposure of Serbian population to zinc, copper, and iron through consumption of canned fish is less than recommended daily reference intakes and there is no risk of reaching toxic levels by consuming fish

Incidental finding of an ovarian epithelial tumor, adequate approach and fertility preservation: A case report

Introduction. Ovarian carcinoma is the fifth leading cause of death in women. In 3–14% of cases, it occurs in women under the age of 40 who intend to have children. Studies have shown a high survival rate if the tumor is diagnosed and treated at an early stage, with a 5-year survival rate of 91.2%, which makes a conservative treatment a valid option. Preserving fertility is safe for grade 1 and 2 of the International Federation of Gynecology and Obstetrics (FIGO) stage I epithelial ovarian carcinomas. A sparing operation involves salpingoophorectomy on the tumor side, multiple biopsies of suspected sites, blind biopsies and infracolic omentectomy, as well as cytological analysis of the wash. Case report. A 25-year-old patient, G0, P0, went to the gynecologist due to severe pain in the lesser pelvis. An ultrasound examination revealed a cystic hypoechoic alteration in the right ovary of about 5 × 6 cm, suspected for torsion, and the patient was urgently operated. A right cystectomy was performed. The histopathological finding of the surgically removed cyst was: endometrioid adenocarcinoma of the ovary, histological grade 2 (HG2) and nuclear grade 2 (NG2), without lymphovascular invasion and no penetration of the capsule, submitted in parts. As the surgery performed did not reveal the degree of ovarian malignant tumor spreading, the FIGO stage could not be determined, and a second operation was necessary to stage the disease according to the FIGO protocol for ovarian cancer. Conclusion. Fertility preservation in patients with malignant ovarian epithelial tumors is a major challenge. The intense desire of the patient to have children has to be satisfied without reducing the success of treatment for this type of disease. The staging of the disease spreading is of paramount importance in order to make an adequate decision regarding the treatment

Exposure assessment in the Serbian population and occurrence ofhistamine and heavy metals in fish and seafood

The aim of this study was to conduct a quantitative exposure assessment of fish-borne histamine, cadmium, mercury and arsenic in the Serbian adult population. The consumption survey of fish/fishery products was administered to 1 000 respondents during 2018. Determination of histamine content was performed on 974 fish; cadmium on 1 909, mercury on 1 911 and arsenic on 1 891 fish and seafood samples during five years (2014–2018). Monte Carlo analysis was used to estimate the intake of histamine/heavy metals from consumption of fish. The mean estimated daily intakes (EDIs) of fish-borne histamine, cadmium, mercury and arsenic by the Serbian adult population were 0.0274 mg kg−1 bw/day, 0.0347 μg kg−1 bw/day, 0.2426 μg kg−1 bw/day and 0.5576 μg kg−1 bw/day, respectively. Due to consumption of fish/seafood, 0.04% of the Serbian population are exposed to histamine, 0.05% to cadmium, 15.42% to mercury and 1.24% to arsenic levels over their respective thresholds