3,831 research outputs found

    Engineering Quantum Jump Superoperators for Single Photon Detectors

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    We study the back-action of a single photon detector on the electromagnetic field upon a photodetection by considering a microscopic model in which the detector is constituted of a sensor and an amplification mechanism. Using the quantum trajectories approach we determine the Quantum Jump Superoperator (QJS) that describes the action of the detector on the field state immediately after the photocount. The resulting QJS consists of two parts: the bright counts term, representing the real photoabsorptions, and the dark counts term, representing the amplification of intrinsic excitations inside the detector. First we compare our results for the counting rates to experimental data, showing a good agreement. Then we point out that by modifying the field frequency one can engineer the form of QJS, obtaining the QJS's proposed previously in an ad hoc manner

    Non-local quantum correlations and detection processes in QFT

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    Quantum detection processes in QFT must play a key role in the description of quantum field correlations, such as the appearance of entanglement, and of causal effects. We consider the detection in the case of a simple QFT model with a suitable interaction to exact treatment, consisting of a quantum scalar field coupled linearly to a classical scalar source. We then evaluate the response function to the field quanta of two-level point-like quantum model detectors, and analyze the effects of the approximation adopted in standard detection theory. We show that the use of the RWA, that characterizes the Glauber detection model, leads in the detector response to non-local terms corresponding to an instantaneously spreading of source effects over the whole space. Other detector models, obtained with non-standard or the no-application of RWA, give instead local responses to field quanta, apart from source independent vacuum contribution linked to preexisting correlations of zero-point field.Comment: 23 page

    Coxiella burnetii Blocks Intracellular Interleukin-17 Signaling in Macrophages

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    Coxiella burnetii is an obligate intracellular bacterium and the etiological agent of Q fever. Successful host cell infection requires the Coxiella type IVB secretion system (T4BSS), which translocates bacterial effector proteins across the vacuole membrane into the host cytoplasm, where they manipulate a variety of cell processes. To identify host cell targets of Coxiella T4BSS effector proteins, we determined the transcriptome of murine alveolar macrophages infected with a Coxiella T4BSS effector mutant. We identified a set of inflammatory genes that are significantly upregulated in T4BSS mutant-infected cells compared to mock-infected cells or cells infected with wild-type (WT) bacteria, suggesting that Coxiella T4BSS effector proteins downregulate the expression of these genes. In addition, the interleukin-17 (IL-17) signaling pathway was identified as one of the top pathways affected by the bacteria. While previous studies demonstrated that IL-17 plays a protective role against several pathogens, the role of IL-17 during Coxiella infection is unknown. We found that IL-17 kills intracellular Coxiella in a dose-dependent manner, with the T4BSS mutant exhibiting significantly more sensitivity to IL-17 than WT bacteria. In addition, quantitative PCR confirmed the increased expression of IL-17 downstream signaling genes in T4BSS mutant-infected cells compared to WT- or mock-infected cells, including the proinflammatory cytokine genes Il1a, Il1b, and Tnfa, the chemokine genes Cxcl2 and Ccl5, and the antimicrobial protein gene Lcn2 We further confirmed that the Coxiella T4BSS downregulates macrophage CXCL2/macrophage inflammatory protein 2 and CCL5/RANTES protein levels following IL-17 stimulation. Together, these data suggest that Coxiella downregulates IL-17 signaling in a T4BSS-dependent manner in order to escape the macrophage immune response

    Smooth quantum-classical transition in photon subtraction and addition processes

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    Recently Parigi et al. [Science 317, 1890 (2007)] implemented experimentally the photon subtraction and addition processes from/to a light field in a conditional way, when the required operations were produced successfully only upon the positive outcome of a separate measurement. It was verified that for a low intensity beam (quantum regime) the bosonic annihilation operator does indeed describe a single photon subtraction, while the creation operator describes a photon addition. Nonetheless, the exact formal expressions for these operations do not always reduce to these simple identifications, and in this connection here we deduce the general superoperators for multiple photons subtraction and addition processes and analyze the statistics of the resulting states for classical field states having an arbitrary intensity. We obtain closed analytical expressions and verify that for classical fields with high intensity (classical regime) the operators that describe photon subtraction and addition processes deviate significantly from simply annihilation and creation operators. Complementarily, we analyze in details such a smooth quantum-classical transition as function of beam intensity for both processes.Comment: 7 pages, 5 figures. To appear in Phys. Rev.

    Microscopic models of quantum jump super-operators

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    We discuss the quantum jump operation in an open system, and show that jump super-operators related to a system under measurement can be derived from the interaction of that system with a quantum measurement apparatus. We give two examples for the interaction of a monochromatic electromagnetic field in a cavity (the system) with 2-level atoms and with a harmonic oscillator (representing two different kinds of detectors). We show that derived quantum jump super-operators have `nonlinear' form which depends on assumptions made about the interaction between the system and the detector. A continuous transition to the standard Srinivas--Davies form of the quantum jump super-operatoris shown

    Implementation of projective measurements with linear optics and continuous photon counting

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    We investigate the possibility of implementing a given projection measurement using linear optics and arbitrarily fast feedforward based on the continuous detection of photons. In particular, we systematically derive the so-called Dolinar scheme that achieves the minimum error discrimination of binary coherent states. Moreover, we show that the Dolinar-type approach can also be applied to projection measurements in the regime of photonic-qubit signals. Our results demonstrate that for implementing a projection measurement with linear optics, in principle, unit success probability may be approached even without the use of expensive entangled auxiliary states, as they are needed in all known (near-)deterministic linear-optics proposals.Comment: 11 pages, 2 figures, updated to the published versio

    Micropropagation of Crotalaria laburnifolia L. – An ethnomedicinally important herbal species

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    A protocol for in vitro shoot multiplication in Crotalaria labumifolia L. through nodal explants was established. Excision and culture of the nodal segments from in vitro developed shoots on fresh MS medium with concentration of BA (1mg/1) facilitated development of multiple shoots. Subsequent cultures enhanced the rate of shoot proliferation. Shoots cultured on ½ MS medium containing NAA (0.5 mg/1) initiated roots well compared with IBA and this is the most suitable protocol studied in C. labumifolia. The present study is the first report on in vitro regeneration in this species&nbsp
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