(2E)-1-(2,5-Dimethyl­thio­phen-3-yl)-3-(3-nitro­phen­yl)prop-2-en-1-one

In the title compound, C15H13NO3S, the benzene ring and the five-membered heterocyclic ring are oriented at a dihedral angle of 12.00 (6)°. In the crystal, C—H⋯O inter­actions generate two types of cyclic motifs, R 2 2(14) and R 2 2(26), connecting the mol­ecules into tapes extending along [101]. In addition, there are π–π stacking inter­actions between the benzene and thio­phene rings with centroid-centroid distances of 3.7263 (14) and 3.7487 (14) Å

2-Amino-4-(3,4-dimeth­oxy­phen­yl)-5,6-dihydro­benzo[h]quinoline-3-carbo­nitrile–3-amino-1-(3,4-dimeth­oxy­phen­yl)-9,10-dihydro­phenanthrene-2,4-dicarbonitrile (1/19)

The asymmetric unit of the 1:19 title co-crystal of 2-amino-4-(3,4-dimeth­oxy­phen­yl)-5,6-dihydro­benzo[h]quinoline-3-carbo­nitrile and 3-amino-1-(3,4-dimeth­oxy­phen­yl)-9,10-dihydro­phenanthrene-2,4-dicarbonitrile, 0.05C22H19N3O2·0.95C24H19N3O2, has the atoms of the fused-ring system and those of the amino, cyano and dimeth­oxy­phenyl substitutents overlapped. The fused-ring system is buckled owing to the ethyl­ene linkage in the central ring with the two flanking aromatic rings being twisted by 31.9 (1)°. The ring of the dimeth­oxy­phenyl substituent is twisted by 72.4 (1)° relative to the amino- and cyano-bearing aromatic ring. In the crystal, mol­ecules are linked by duplex amine N—H⋯O(meth­oxy) hydrogen bonds in a cyclic association [graph-set R 2 2(7)], generating a helical chain structure extending along [201]

1-Chloro-1-[(4-nitro­phen­yl)hydrazinyl­idene]propan-2-one

The non-H atoms of the title compound, C9H8ClN3O3, lie approximately on a plane (r.m.s. deviation = 0.111 Å), and the C=N double bond has a Z configuration. In the crystal, adjacent mol­ecules are linked by an N—H⋯Ocarbon­yl hydrogen bond, forming a chain running along [101]

N-[(E)-Anthracen-9-yl­methyl­idene]-3,4-dimethyl-1,2-oxazol-5-amine

In the title compound, C20H16N2O, an intra­molecular C—H⋯N forms an S(6) ring motif. In the crystal, the mol­ecules are stacked with their anthracene ring planes in sheets along [100]

Effects of acute and sub-chronic ammonium nitrate exposure on rat liver and blood tissues

Use of fertilizers like ammonium nitrate (NH4NO3) for agricultural purposes has increasingly contaminated the ecosystem with nitrate and/or nitrites. Nitrite is a toxic substance that can cause multiple physiological effects if allowed to build up to high concentrations in animals such as methemoglobinemia. This work is concerned with the study of short term (3 days intoxication) and midterm (over 21 days) NH4NO3 exposure to wistar rats at the dose of 250 mg/Kg. Under these conditions, some hematological and biochemical parameters were affected. Methemoglobinemia, increase in serum nitrates as well as a hepatic cytotoxicity indicated by an increase in bilirubin and transaminases levels were observed

1-Chloro-1-[(4-meth­oxy­phen­yl)hydrazinyl­idene]propan-2-one

The non-H atoms of the title compound, C10H11ClN2O2, lie nearly on a plane (r.m.s. deviation = 0.150 Å), and the C=N double bond has a Z configuration. In the crystal, adjacent mol­ecules are linked by an N—H⋯Ocarbon­yl hydrogen bond, forming a chain running along [201]

1-Chloro-1-[(4-methyl­phen­yl)hydrazinyl­idene]propan-2-one

The asymmetric unit of the title compound, C10H11ClN2O, contains two mol­ecules. The non-H atoms of each mol­ecule lie approximately on a plane (r.m.s. deviations = 0.062 and 0.110 Å), and the C=N double bond has a Z-configuration in both independent mol­ecules. In the crystal, adjacent mol­ecules are linked by N—H⋯Ocarbon­yl hydrogen bonds, forming chains running along [100]

Hepatitis B virus-related post-infectious glomerulonephritis: A case report

Hepatitis B virus infection is an uncommon cause of acute glomerulonephritis. We present a case of acute glomerulonephritis revealing a chronic viral  hepatitis B. A 45 year-old man was admitted in the nephrology department of Hassan II university hospital (Fez, Morocco) for nephritic syndrome with  advanced acute kidney injury. The investigations have revealed viral hepatitis B with a positive HBV-DNA and Others viral serology tests were negative. Renal biopsy showed a diffuse and global endocapillary proliferation without extra-capillary proliferation; and global deposits of C3 and Ig G On  immunofluorescence. There wasn't any other infectious cause. We thus retained the diagnosis of hepatitis B virus-associated acute  glomerulonephritis. He was given entecavir and corticosteroids. Three months later, the evolution was marked by the normalization of renal function, negativity of proteinuria and HBV DNA became undetectable. There was no relapse of glomerulonephritis and HBV viral load was still negative after one year follow-up