Covid-19 vaccines and the competition between independent and politicised models of regulation

The regulatory approaches used to approve Covid-19 vaccines vary substantially across different countries. While some states assign responsibility for vaccine approval to independent regulatory agencies, politicians in other states have greater scope to influence decision-making. Eva Heims and Slobodan Tomic write that the current push to roll out vaccination programmes as quickly as possible is shining a light on competition between these independent and politicised models of regulation

Coexistence of Superconductivity and Spin Density Wave orderings in the organic superconductor (TMTSF)_2PF_6

The phase diagram of the organic superconductor (TMTSF)_2PF_6 has been revisited using transport measurements with an improved control of the applied pressure. We have found a 0.8 kbar wide pressure domain below the critical point (9.43 kbar, 1.2 K) for the stabilisation of the superconducting ground state featuring a coexistence regime between spin density wave (SDW) and superconductivity (SC). The inhomogeneous character of the said pressure domain is supported by the analysis of the resistivity between T_SDW and T_SC and the superconducting critical current. The onset temperature T_SC is practically constant (1.20+-0.01 K) in this region where only the SC/SDW domain proportion below T_SC is increasing under pressure. An homogeneous superconducting state is recovered above the critical pressure with T_SC falling at increasing pressure. We propose a model comparing the free energy of a phase exhibiting a segregation between SDW and SC domains and the free energy of homogeneous phases which explains fairly well our experimental findings.Comment: 13 pages, 10 figures, revised v: fig.9 added, section 4.2 rewritten, accepted v: sections 4&5 improve

Fiber-optic interferometric sensor of magnetic field for structural health monitoring

AbstractIn this paper we report on results of measurement of AC and DC magnetic field by fiber-optic interferometric sensor. Principle of operation is based on change of length of optical path cavity between the magnetostrictive wire and fiber-optic tip. Any change of the outside magnetic field causes elongation or contraction of the sensing wire. Using a fiber-optic sensing configuration based on single-mode 3×3 coupler and low-coherence interferometry we were able to read the instant separation between the wire and fiber ends with accuracy of about 50 nm. This separation corresponds with the intensity of the magnetic field in the range of 50 nT to 800 μT what is measured by using well calibrated magnetometer. The sensor is dedicated for on-line structural health monitoring of composite materials made of carbon reinforced epoxy matrix with integrated magnetic particles. Due to final purpose to be embedded in the structure, the sensor is designed to have small overall size of about 250 μm in outside diameter

Linearization of multichannel amplifiers with the injection of second harmonics into the amplifier and predistortion circuit

A linearization technique that uses the injection of the fundamental signal second harmonics together with the fundamental signals at the amplifier input has been extended in this paper by introducing the injection the second harmonics into nonlinear microwave amplifier and so-called predistortion circuit. Predistortion circuit produces the third-order intermodulation signals that are injected at the amplifier input together with the second harmonics making the linearization procedure more independent on the phase variation of the second harmonics. In addition, a considerably better improvement is attained for the power of fundamental signals close to 1-dB compression point by applying the linearization technique proposed in this paper in comparison to the linearization with the injection of the second harmonics merely in the nonlinear amplifier

4-Lump kinetic model for hydrotreated gas oil catalytic cracking

This study has monitored the influence of one of the hydrodesulphurisation process parameters - H2/CH ratio on the properties of three catalytic cracking products (gas, petrol, light cyclic oil, and heavy cyclic oil ). The microactivity test (MAT) was applied to all kinetic measurements. A 4-lump, non-isothermal and non-stationary kinetic model for the fixed, plug-flow MAT reactor was developed to model catalytic cracking of hydrotreated gas oil. Kinetic constants were estimated by the Nelder Mead method. The product yields predicted by the model showed good confirmity with experimental data

Enhanced Thermoelectric Power and Electronic Correlations in RuSe2_2

We report the electronic structure, electric and thermal transport properties of Ru$_{1-x}$Ir$_{x}$Se$_2$ ($x \leq 0.2$). RuSe$_2$ is a semiconductor that crystallizes in a cubic pyrite unit cell. The Seebeck coefficient of RuSe$_2$ exceeds -200 $\mu$V/K around 730 K. Ir substitution results in the suppression of the resistivity and the Seebeck coefficient, suggesting the removal of the peaks in density of states near the Fermi level. Ru$_{0.8}$Ir$_{0.2}$Se$_{2}$ shows a semiconductor-metal crossover at about 30 K. The magnetic field restores the semiconducting behavior. Our results indicate the importance of the electronic correlations in enhanced thermoelectricity of RuSb$_{2}$.Comment: 6 pages, 4 figure

Anisotropic charge dynamics in the quantum spin-liquid candidate κ\kappa-(BEDT-TTF)2_2Cu2_2(CN)3_3

We have in detail characterized the anisotropic charge response of the dimer Mott insulator $\kappa$-(BEDT-TTF)$_2$\-Cu$_2$(CN)$_3$ by dc conductivity, Hall effect and dielectric spectroscopy. At room temperature the Hall coefficient is positive and close to the value expected from stoichiometry; the temperature behavior follows the dc resistivity $\rho(T)$. Within the planes the dc conductivity is well described by variable-range hopping in two dimensions; this model, however, fails for the out-of-plane direction. An unusually broad in-plane dielectric relaxation is detected below about 60 K; it slows down much faster than the dc conductivity following an Arrhenius law. At around 17 K we can identify a pronounced dielectric anomaly concomitantly with anomalous features in the mean relaxation time and spectral broadening. The out-of-plane relaxation, on the other hand, shows a much weaker dielectric anomaly; it closely follows the temperature behavior of the respective dc resistivity. At lower temperatures, the dielectric constant becomes smaller both within and perpendicular to the planes; also the relaxation levels off. The observed behavior bears features of relaxor-like ferroelectricity. Because heterogeneities impede its long-range development, only a weak tunneling-like dynamics persists at low temperatures. We suggest that the random potential and domain structure gradually emerge due to the coupling to the anion network.Comment: 14 pages, 13 figure

PRM51 From Clinical Trial to Real-World Evidence: A Systematic Approach to Identifying Data Sources for Observational Research

Edifici industrial de dos cossos de planta baixa i tres plantes pis acabades amb mansarda. Destaca el nombre i dimensions de les obertures que permeten una gran entrada de llum a l'interior i l'amplitud de les plantes diàfanes.Digitalitzat per Tecnodo