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A comparative study of far-field tsunami amplitudes and ocean-wide propagation properties: Insight from major trans-Pacific tsunamis of 2010-2015
Copyright © The Author(s) 2018. We studied ocean-wide propagation properties of four recent trans-Pacific tsunamis based on deep-ocean measurements across the Pacific Ocean. First, we analyzed and simulated the 16 September 2015 tsunami generated by the Illapel (Chile) earthquake (Mw 8.4) and compared its ocean-wide propagation with those of three other events: the 2014 Iquique (Mw 8.2), 2010 Maule (Mw 8.8) and 2011 Tohoku (Mw 9.0). The Illapel and Maule tsunami sources are located close to each other and we reconstructed the source spectrum of the larger (i.e. Maule) tsunami by applying spectral deconvolution using the smaller (i.e. Illapel) tsunami as the empirical Green's function. The initial negative phase was found for all four events with durations of 8–29 (Iquique), 20–35 (Illapel), 22–70 (Maule) and 40–79 (Tohoku) min, with the maximum amplitudes of 0.11–0.26, 0.4–0.7, 0.5–2.9 and 1.9–2.5 cm, and the amplitude ratios to the first elevation phases of 20–40 per cent, 22–41 per cent, 29–61 per cent and 12–67 per cent, respectively. Unlike other studies, our results revealed that the duration ({D_{ini}}$ $) and amplitude ({A_{ini}}) of the initial negative phase are directly proportional to the earthquake magnitude ({M_w}$ $) with equations: {M_w} = \;6.129 + 1.629\;{\rm{log}}( {{D_{ini}}} ) and {M_w} = \;8.676 + 0.706\;{\rm{log}}( {{A_{ini}}} )$ $. No relationships were observed between these parameters (i.e. {D_{ini}} and {A_{ini}}$ $) and distance from the source. The amplitudes of far-field DART waves do not vary with distance or strike angle, and depend only on the {M_w}. The average far-field deep-ocean amplitudes ({A_{tsu}}$ $) for the Iquique, Illapel, Maule and Tohoku tsunamis were 0.9, 1.7, 6.0 and 15.0 cm, respectively, yielding the equation: {M_w} = \;8.245 + 0.665\;{\rm{log}}( {{A_{tsu}}} ).Brunel Research Initiative and Enterprise Fun
Ultrathin 2 nm gold as ideal impedance-matched absorber for infrared light
Thermal detectors are a cornerstone of infrared (IR) and terahertz (THz)
technology due to their broad spectral range. These detectors call for suitable
broad spectral absorbers with minimalthermal mass. Often this is realized by
plasmonic absorbers, which ensure a high absorptivity butonly for a narrow
spectral band. Alternativly, a common approach is based on impedance-matching
the sheet resistance of a thin metallic film to half the free-space impedance.
Thereby, it is possible to achieve a wavelength-independent absorptivity of up
to 50 %, depending on the dielectric properties of the underlying substrate.
However, existing absorber films typicallyrequire a thickness of the order of
tens of nanometers, such as titanium nitride (14 nm), whichcan significantly
deteriorate the response of a thermal transducers. Here, we present the
application of ultrathin gold (2 nm) on top of a 1.2 nm copper oxide seed layer
as an effective IR absorber. An almost wavelength-independent and long-time
stable absorptivity of 47(3) %, ranging from 2 m to 20 m, could be
obtained and is further discussed. The presented gold thin-film represents
analmost ideal impedance-matched IR absorber that allows a significant
improvement of state-of-the-art thermal detector technology
Injection of Human Bone Marrow and Mononuclear Cell Extract into Infarcted Mouse Hearts Results in Functional Improvement
Background: We have previously shown that mouse whole bone marrow cell (BMC) extract results in improvement of cardiac function and decreases scar size in a mouse model of myocardial infarction (MI), in the absence of intact cells. It is not clear if thes
Effect of obesity on intraoperative bleeding volume in open gastrectomy with D2 lymph-node dissection for gastric cancer
<p>Abstract</p> <p>Background</p> <p>To investigate the effect of obesity on open gastrectomy with D2 lymph-node dissection.</p> <p>Methods</p> <p>Between January 2005 and March 2007, 100 patients with preoperatively diagnosed gastric cancer who underwent open gastrectomy with D2 lymph-node dissection were enrolled in this study. Of these, 61 patients underwent open distal gastrectomy (ODG) and 39 patients underwent open total gastrectomy (OTG). Patients were classified as having a high body-mass index (BMI; ≥ 25.0 kg/m<sup>2</sup>; <it>n </it>= 21) or a normal BMI (<25.0 kg/m<sup>2</sup>; <it>n </it>= 79). The visceral fat area (VFA) and subcutaneous fat area (SFA) were assessed as identifiers of obesity using FatScan software. Patients were classified as having a high VFA (≥ 100 cm<sup>2</sup>; <it>n </it>= 34) or a normal VFA (<100 cm<sup>2</sup>; <it>n </it>= 66). The relationship between obesity and short-term patient outcomes after open gastrectomy was evaluated. Patients were classified as having high intraoperative blood loss (IBL; ≥ 300 ml; <it>n </it>= 42) or low IBL (<300 ml; <it>n </it>= 58). Univariate and multivariate analyses were used to identify predictive factors for high IBL.</p> <p>Results</p> <p>Significantly increased IBL was seen in the following: patients with high BMI versus normal BMI; patients with gastric cancer in the upper third of the stomach versus gastric cancer in the middle or lower third of the stomach; patients who underwent OTG versus ODG; patients who underwent splenectomy versus no splenectomy; and patients with high VFA versus low VFA. BMI and VFA were significantly greater in the high IBL group than in the low IBL group. There was no significant difference in morbidity between the high IBL group and the low IBL group. Multivariate analysis revealed that patient age, OTG and high BMI or high VFA independently predicted high IBL.</p> <p>Conclusion</p> <p>It is necessary to perform operative manipulations with particular care in patients with high BMI or high VFA in order to reduce the IBL during D2 gastrectomy.</p
Bone marrow transplantation modulates tissue macrophage phenotype and enhances cardiac recovery after subsequent acute myocardial infarction
AbstractBackgroundBone marrow transplantation (BMT) is commonly used in experimental studies to investigate the contribution of BM-derived circulating cells to different disease processes. During studies investigating the cardiac response to acute myocardial infarction (MI) induced by permanent coronary ligation in mice that had previously undergone BMT, we found that BMT itself affects the remodelling response.Methods and resultsCompared to matched naive mice, animals that had previously undergone BMT developed significantly less post-MI adverse remodelling, infarct thinning and contractile dysfunction as assessed by serial magnetic resonance imaging. Cardiac rupture in male mice was prevented. Histological analysis showed that the infarcts of mice that had undergone BMT had a significantly higher number of inflammatory cells, surviving cardiomyocytes and neovessels than control mice, as well as evidence of significant haemosiderin deposition. Flow cytometric and histological analyses demonstrated a higher number of alternatively activated (M2) macrophages in myocardium of the BMT group compared to control animals even before MI, and this increased further in the infarcts of the BMT mice after MI.ConclusionsThe process of BMT itself substantially alters tissue macrophage phenotype and the subsequent response to acute MI. An increase in alternatively activated macrophages in this setting appears to enhance cardiac recovery after MI
MIQuant – Semi-Automation of Infarct Size Assessment in Models of Cardiac Ischemic Injury
BACKGROUND: The cardiac regenerative potential of newly developed therapies is traditionally evaluated in rodent models of surgically induced myocardial ischemia. A generally accepted key parameter for determining the success of the applied therapy is the infarct size. Although regarded as a gold standard method for infarct size estimation in heart ischemia, histological planimetry is time-consuming and highly variable amongst studies. The purpose of this work is to contribute towards the standardization and simplification of infarct size assessment by providing free access to a novel semi-automated software tool. The acronym MIQuant was attributed to this application. METHODOLOGY/PRINCIPAL FINDINGS: Mice were subject to permanent coronary artery ligation and the size of chronic infarcts was estimated by area and midline-length methods using manual planimetry and with MIQuant. Repeatability and reproducibility of MIQuant scores were verified. The validation showed high correlation (r(midline length) = 0.981; r(area) = 0.970 ) and agreement (Bland-Altman analysis), free from bias for midline length and negligible bias of 1.21% to 3.72% for area quantification. Further analysis demonstrated that MIQuant reduced by 4.5-fold the time spent on the analysis and, importantly, MIQuant effectiveness is independent of user proficiency. The results indicate that MIQuant can be regarded as a better alternative to manual measurement. CONCLUSIONS: We conclude that MIQuant is a reliable and an easy-to-use software for infarct size quantification. The widespread use of MIQuant will contribute towards the standardization of infarct size assessment across studies and, therefore, to the systematization of the evaluation of cardiac regenerative potential of emerging therapies
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