250 research outputs found
Spectral Correlation in Incommensurate Multi-Walled Carbon Nanotubes
We investigate the energy spectra of clean incommensurate double-walled
carbon nanotubes, and find that the overall spectral properties are described
by the so-called critical statistics of Anderson metal-insulator transition. In
the energy spectra, there exist three different regimes characterized by
Wigner-Dyson, Poisson, and semi-Poisson distributions. This feature implies
that the electron transport in incommensurate multi-walled nanotubes can be
either diffusive, ballistic, or intermediate between them, depending on the
position of the Fermi energy.Comment: final version to appear in Phys. Rev. Let
ISSUES IN REFORMING TARIFF-RATE IMPORT QUOTAS IN THE AGREEMENT ON AGRICULTURE IN THE WTO
Contents: The Economics of Tariff Rate Quotas and the Effects of Trade Liberalization; TRQs and GATT Rules; An Overview of Tariffs, Quotas and Imports Worldwide; TRQs in the European Union; U.S. TRQs for Sugar, Tobacco and Peanuts; Dairy TRQs in the United States; Tariff Rate Quota Implementation and Administration by Developing Countries; Management of Tariff Rate Quotas in Korea and Japan; Tariff Rate Quota Administration in Canadian Agriculture; The Case of Australia and New Zealand Facing TRQs; The 1999 WTO Panel Report on the EU's Common Market Organization for Bananas; AssessmentInternational Relations/Trade,
DNA demethylation is initiated in the central cells of Arabidopsis and rice
Cytosine methylation is a DNA modification with important regulatory functions in eukaryotes. In flowering plants, sexual reproduction is accompanied by extensive DNA demethylation, which is required for proper gene expression in the endosperm, a nutritive extraembryonic seed tissue. Endosperm arises from a fusion of a sperm cellcarried in the pollen and a female central cell. Endosperm DNA demethylation is observed specifically on the chromosomes inherited from the central cell in Arabidopsis thaliana, rice, and maize, and requires the DEMETER DNA demethylase in Arabidopsis. DEMETER is expressed in the central cell before fertilization, suggesting thatendosperm demethylation patterns are inherited from the central cell. Down-regulation of the MET1 DNA methyltransferase has also been proposed to contribute to central cell demethylation. However, with the exception of three maize genes, central cell DNA methylation has not been directly measured, leaving the origin and mechanism of endosperm demethylation uncertain. Here, we report genome-wide analysis of DNA methylation in the central cells of Arabidopsis and rice-species that diverged 150 million years ago-as well as in rice egg cells. We find that DNA demethylation in both species is initiated in central cells, which requires DEMETER in Arabidopsis. However, we do not observe a global reduction of CG methylation that would be indicative of lowered MET1 activity; on the contrary, CG methylation efficiency is elevated in female gametescompared with nonsexual tissues. Our results demonstrate that locus-specific, active DNA demethylation in the central cell is the origin ofmaternal chromosome hypomethylation in the endosperm.OAIID:RECH_ACHV_DSTSH_NO:T201700144RECH_ACHV_FG:RR00200001ADJUST_YN:EMP_ID:A076495CITE_RATE:9.423FILENAME:2016_PNAS_박경혁.pdfDEPT_NM:생명과학부EMAIL:[email protected]_YN:YFILEURL:https://srnd.snu.ac.kr/eXrepEIR/fws/file/a82f27c2-3a24-42c3-844c-a3446849b316/linkCONFIRM:
Functional Role of the Polymorphic 647 T/C Variant of ENT1 (SLC29A1) and Its Association with Alcohol Withdrawal Seizures
Adenosine is involved in several neurological and behavioral disorders including alcoholism. In cultured cell and animal studies, type 1 equilibrative nucleoside transporter (ENT1, slc29a1), which regulates adenosine levels, is known to regulate ethanol sensitivity and preference. Interestingly, in humans, the ENT1 (SLC29A1) gene contains a non-synonymous single nucleotide polymorphism (647 T/C; rs45573936) that might be involved in the functional change of ENT1.
Our functional analysis showed that prolonged ethanol exposure increased adenosine uptake activity of mutant cells (ENT1-216Thr) compared to wild-type (ENT1-216Ile) transfected cells, which might result in reduced extracellular adenosine levels. We found that mice lacking ENT1 displayed increased propensity to ethanol withdrawal seizures compared to wild-type littermates. We further investigated a possible association of the 647C variant with alcoholism and the history of alcohol withdrawal seizures in subjects of European ancestry recruited from two independent sites. Analyses of the combined data set showed an association of the 647C variant and alcohol dependence with withdrawal seizures at the nominally significant level.
Together with the functional data, our findings suggest a potential contribution of a genetic variant of ENT1 to the development of alcoholism with increased risk of alcohol withdrawal-induced seizures in humans
An Upper Bound on the Decay tau -> mu gamma from Belle
We have performed a search for the lepton-flavor-violating decay tau -> mu
gamma using a data sample of 86.3fb^{-1} accumulated by the Belle detector at
KEK. No evidence for a signal is seen, and we set an upper limit for the
branching fraction of B(tau -> mu gamma) < 3.1 x 10^{-7} at the 90% confidence
level.Comment: 6 pages, 4 figuresm, submitted to Phys. Rev. Let
Observation of a narrow charmonium-like state in exclusive B+ -> K+ pi+pi- J/psi decays
We report the observation of a narrow charmonium-like state produced in the
exclusive decay process B+ -> K+ pi+pi- J/psi. This state, which decays into
pi+pi- J/psi, has a mass of 3872.0+-0.6(stat)+-0.5(syst) MeV, a value that is
very near the M_D + M_D* mass threshold. The results are based on an analysis
of 152M B-Bbar events collected at the Upsilon(4S) resonance in the Belle
detector at the KEKB collider. The statistical significance of the signal is in
excess of 10 sigma.Comment: 10 pages 4 figures, submitted to Physical Review Letter
Observation of
We report the first observation of the flavor-changing neutral current decay
and an improved measurement of the decay , where represents an electron or a muon, with a data
sample of 140 fb accumulated at the resonance with the
Belle detector at KEKB. The results for the branching fractions are and
, where the first error is statistical, the second is systematic and
the third is from model dependence.Comment: 11 pages, 2 figures, submitted to PR
Search for B^- --> J/psi Lambda p-bar decay
We report the results of a search for B^{-} \to \jpsi \Lambda \pbar based
on a data set of 78 fb data collected at the resonance
with the Belle detector at the KEKB asymmetric collider. No
substantial signal is found, and we set the branching fraction upper limit
{\cal B}(B^{-} \to \jpsi \Lambda \pbar) < 4.1 \times 10^{-5} at 90%
confidence level.Comment: 8 pages, 2 figures, submitted to Phys. Rev.
Charmless Hadronic Two-Body B Meson Decays
We report the results of a study of two-body B meson decays to the complete
set of K pi, pi pi, and K K final states. The study is performed on a data
sample of 31.7 +/- 0.3 million B B-bar events recorded on the Upsilon(4S)
resonance by the Belle experiment at KEKB. We observe significant signals in
all K pi final states and in the pi+ pi- and pi+ pi0 final states. We set
limits on the pi0 pi0 and K K final states. A search is performed for
partial-rate asymmetries between conjugate states for flavor-specific final
states.Comment: Submitted to PR
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