Extent of Empowerment of Women Entrepreneurs on Entrepreneurial and Technological Empowerment

Empowerment of women entrepreneurs in the context of technology entails building up the abilities and skills of women to gain insight into the issues affecting them and also building up their capacity to voice their concerns. Technological empowerment of women entrepreneurs will open up avenues to further nrichment. By the use of technology women can broaden the scope of their activities. Hence the present paper focused on analyzing the entrepreneurial and technological empowerment of women entrepreneurs. Majority of the women entrepreneurs had medium level of entrepreneurial and low level of technological empowerment

Micronutrients in HIV: A Bayesian MetaAnalysis

Background: Approximately 28.5 million people living with HIV are eligible for treatment (CD4&500), but currently have no access to antiretroviral therapy. Reduced serum level of micronutrients is common in HIV disease. Micronutrient supplementation (MNS) may mitigate disease progression and mortality. Objectives: We synthesized evidence on the effect of micronutrient supplementation on mortality and rate of disease progression in HIV disease. Methods: We searched MEDLINE, EMBASE, the Cochrane Central, AMED and CINAHL databases through December 2014, without language restriction, for studies of greater than 3 micronutrients versus any or no comparator. We built a hierarchical Bayesian random effects model to synthesize results. Inferences are based on the posterior distribution of the population effects; posterior distributions were approximated by Markov chain Monte Carlo in OpenBugs. Principal Findings: From 2166 initial references, we selected 49 studies for full review and identified eight reporting on disease progression and/or mortality. Bayesian synthesis of data from 2,249 adults in three studies estimated the relative risk of disease progression in subjects on MNS vs. control as 0.62 (95% credible interval, 0.37, 0.96). Median number needed to treat is 8.4 (4.8, 29.9) and the Bayes Factor 53.4. Based on data reporting on 4,095 adults reporting mortality in 7 randomized controlled studies, the RR was 0.84 (0.38, 1.85), NNT is 25 (4.3, ∞). Conclusions: MNS significantly and substantially slows disease progression in HIV+ adults not on ARV, and possibly reduces mortality. Micronutrient supplements are effective in reducing progression with a posterior probability of 97.9%. Considering MNS low cost and lack of adverse effects, MNS should be standard of care for HIV+ adults not yet on ARV

Extent of Empowerment of Women Entrepreneurs on Entrepreneurial and Technological Empowerment

Empowerment of women entrepreneurs in the context of technology entails building up the abilities and skills of women to gain insight into the issues affecting them and also building up their capacity to voice their concerns. Technological empowerment of women entrepreneurs will open up avenues to further nrichment. By the use of technology women can broaden the scope of their activities. Hence the present paper focused on analyzing the entrepreneurial and technological empowerment of women entrepreneurs. Majority of the women entrepreneurs had medium level of entrepreneurial and low level of technological empowerment

Abdominal-A mediated repression of Cyclin E expression during cell-fate specification in the Drosophila central nervous system

Homeotic/Hox genes are known to specify a given developmental pathway by regulating the expression of downstream effector genes. During embryonic CNS development of Drosophila, the Hox protein Abdominal-A (AbdA) is required for the specification of the abdominal NB6-4 lineage. It does so by down regulating the expression of the cell cycle regulator gene Dcyclin E (CycE). CycE is normally expressed in the thoracic NB6-4 lineage to give rise to mixed lineage of neurons and glia, while only glial cells are produced from the abdominal NB6-4 lineage due to the repression of CycE by AbdA. Here we investigate how AbdA represses the expression of CycE to define the abdominal fate of a single NB6-4 precursor cell. We analyze, both in vitro and in vivo, the regulation of a 1.9 kb CNS-specific CycE enhancer element in the abdominal NB6-4 lineage. We show that CycE is a direct target of AbdA and it binds to the CNS specific enhancer of CycE to specifically repress the enhancer activity in vivo. Our results suggest preferential involvement of a series of multiple AbdA binding sites to selectively enhance the repression of CycE transcription. Furthermore, our data suggest a complex network to regulate CycE expression where AbdA functions as a key regulator

Novel Behavior of Gd 3+ Ion in La 2 Al 2 Gd 2 O 9 Phosphor Prepared via Solid State Reaction Method

Abstract