Spray‐dried formulations rich in malvidin from tintorera grape wastes: Characterization, stability, and storage

Indexación ScopusThis research was focused on developing means of Tintorera grape (Vitis vinifera L.) waste recovery, devising new value‐added uses for that material and optimizing of anthocyanin‐rich formulations by spray‐drying in order to obtain novel ingredients, all for food industry use. First, the identification of phenolic compounds in Tintorera grape extracts by HPLC‐DAD‐ESI‐MSn enabled characterization of the raw material’s health‐promoting characteristics. Maintaining the spray‐dried products for 4 weeks’ storage enabled study of the formulation’s loss of anthocyanins and antioxi-dant properties due to drying process temperatures as well as analysis of the retention and stability of such compounds under different conditions (20 and 40 °C). Tintorera grapes presented a significant amount of Malvidin 3‐O‐hex (5.66 mg g−1 DW). Anthocyanins in spray‐dried formulations were stable for 4 weeks. Optimal conditions in the spray‐dryer facilitated the products’ antioxidant ca-pacity; for instance, using 10% maltodextrin (w:v) at 90 °C inlet temperature had a little influence on the reduction in encapsulated malvidin 3‐O‐hex (15%) and presented 3.35 mg GAE g−1 DW of total polyphenol contents, 98.62 μmol Trolox (FRAP assay), and 39.97 μmol Trolox (DPPH assay). Principal component analyses (PCA) showed a high degree of dependence between anthocyanin content and maintenance of antioxidant capacity during storage. These results offer a promising alternative for the industrial management of wine‐making wastes in order to implement a sustainable protocol for development of Tintorera grape extracts rich in bioactive compounds for new bev-erages and functional foods. © 2021 by the author. Licensee MDPI, Basel, Switzerland.https://www.mdpi.com/2227-9717/9/3/51

Resveratrol biotechnological applications: enlightening its antimicrobial and antioxidant properties

Introduction Resveratrol (3,5,4'-trihydroxy-trans-stilbene) is a polyphenol obtained from diverse groups of plants, especially in the muscadine grape, red wine, lingonberry, cranberry and redcurrant. Resveratrol's health benefits were first highlighted in the study of the French paradox, which opened up an expansive research endeavor into this compound. Ever since, an array of pharmacological activities, including antioxidant, antiaging, anti-inflammatory, anti-cancer and antidiabetic have been attributed to resveratrol. For many polyphenols, low solubility in biological fluids, as well as by rapid in vivo metabolization, limits their bioavailability. However, improving resveratrol formulation could enhance oral bioavailability and have other beneficial properties. The development of innovative methodological approaches, such as the utilization of innovative formulations has been developed to overcome these limitations and provide a considerable therapeutic amount of resveratrol. Results In this narrative review, a brief outline of historical perspectives of resveratrol is provided, together with an extensive and inclusive overview of various approaches and contemporary developments on the bioavailability, pharmacodynamics and pharmacokinetics of this nutraceutical, along with its biotechnological applications and drug formulations.(undefined)info:eu-repo/semantics/publishedVersio