29 research outputs found

    "Investigator initiated trials" - Wie schwierig sind sie wirklich; praktische Beispiele

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    Tackling multiplicity of equilibria with Gröbner bases

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    Multiplicity of equilibria is a prevalent problem in many economic models. Often equilibria are characterized as solutions to a system of polynomial equations. This paper gives an introduction to the application of GrÄobner basis methods for ¯nding all solutions of a polynomial system. The Shape Lemma, a key result from algebraic geometry, states under mild assumptions that a given equilibrium system has the same solution set as a much simpler triangular system. Essentially the computation of all solutions then reduces to ¯nding all roots of a single polynomial in a single unknown. The software package Singular computes the equivalent simple system. If all coeficients in the original equilibrium equations are rational numbers or parameters then the GrÄobner basis computations of Singular are exact. This fact implies that the GrÄobner basis methods cannot only be used for a numerical approximation of equilibria but in fact may allow the proof of theoretical results for the underlying economic model. Three economic applications illustrate that without much prior knowledge of algebraic geometry GrÄobner basis methods can be easily applied to gain interesting insights into many modern economic models

    Individualisierung medikamentoeser Therapie? Implikationen der Pharmakogenetik fuer Patienten und Gesundheitswesen

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    Available from TIB Hannover: F04B1477 / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekSIGLEBundesministerium fuer Bildung und Forschung (BMBF), Bonn (Germany)DEGerman

    Long-run UIP holds even in the short run

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    The failure of uncovered interest rate parity to explain short-term interest rate movements is well documented. We show that short-term changes in long-term interest rates do help to explain short-term exchange rate movements. The relationship gets stronger over our sample period, as the liquidity of the exchange rate market increases. We also show that controlling for time-varying exchange rate risk also helps to improve the fit of the relationship
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