January reversal in the US weekend effect;

Average returns for small firm size portfolios tend to decrease during the week in January, with Monday returns highest and Friday lowest. More striking are the results after controlling for Mondays and Fridays in the first and the last 3 weeks of January. Monday returns in this first week are significantly positive and inversely related to size. Monday returns are also significantly positive for the small firm size portfolio in the last 3 weeks of January. But returns on Friday are insignificantly different from zero after controlling for Fridays in the first week and the last three weeks of January. The first Monday in January is particularly critical to the reversal of the end-of-the-week effect at the turn-of-the-year, with abnormal demand for stocks following the first weekend of a new calendar year possibly responsible for this anomaly within an anomaly

January reversal in the US weekend effect;

Average returns for small firm size portfolios tend to decrease during the week in January, with Monday returns highest and Friday lowest. More striking are the results after controlling for Mondays and Fridays in the first and the last 3 weeks of January. Monday returns in this first week are significantly positive and inversely related to size. Monday returns are also significantly positive for the small firm size portfolio in the last 3 weeks of January. But returns on Friday are insignificantly different from zero after controlling for Fridays in the first week and the last three weeks of January. The first Monday in January is particularly critical to the reversal of the end-of-the-week effect at the turn-of-the-year, with abnormal demand for stocks following the first weekend of a new calendar year possibly responsible for this anomaly within an anomaly

Acculturation and Disparities in Telemedicine Readiness: A National Study.

Telemedicine provided older adults the ability to safely seek care during the coronavirus disease (COVID-19) pandemic. This study aimed to evaluate the potential impact of acculturation factors in telemedicine uptake between ethnic groups. As part of the National Health and Aging Trends Study 2018 survey, 303 participants (≥65 years) were interviewed. We assessed the impact of acculturation on telemedicine readiness by race and ethnicity. Compared to the white non-Hispanic immigrant population, Hispanic and Asian/Pacific Islander (API) populations had significantly lower telemedicine readiness and uptake. Limited English proficiency or older age at the time of migration was associated with telemedicine unreadiness and uptake in the Hispanic and API populations. Our findings suggested that acculturation factors play a substantial role in telemedicine uptake among older adult immigrants in the United States. Therefore, acculturation factors should be considered when promoting and adopting telemedicine technologies in older adults

Diagnostisches und therapeutisches Vorgehen in der Akutphase nach kranio-zervikalem Beschleunigungstrauma (sog. Schleudertrauma) : Empfehlungen einer schweizerischen Arbeitsgruppe

https://digitalrepository.unm.edu/abq_eh_news/1514/thumbnail.jp

Wearable Based Calibration of Contactless In-home Motion Sensors for Physical Activity Monitoring in Community-Dwelling Older Adults

Passive infrared motion sensors are commonly used in telemonitoring applications to monitor older community-dwelling adults at risk. One possible use case is quantification of in-home physical activity, a key factor and potential digital biomarker for healthy and independent aging. A major disadvantage of passive infrared sensors is their lack of performance and comparability in physical activity quantification. In this work, we calibrate passive infrared motion sensors for in-home physical activity quantification with simultaneously acquired data from wearable accelerometers and use the data to find a suitable correlation between in-home and out-of-home physical activity. We use data from 20 community-dwelling older adults that were simultaneously provided with wireless passive infrared motion sensors in their homes, and a wearable accelerometer for at least 60 days. We applied multiple calibration algorithms and evaluated results based on several statistical and clinical metrics. We found that using even relatively small amounts of wearable based ground-truth data over 7–14 days, passive infrared based wireless sensor systems can be calibrated to give largely better estimates of older adults’ daily physical activity. This increase in performance translates directly to stronger correlations of measured physical activity levels with a variety of age relevant health indicators and outcomes known to be associated with physical activity

A geography-based critique of new US biofuels regulations

The new renewable fuels standard (RFS 2) aims to distinguish corn-ethanol that achieves a 20% reduction in greenhouse gas (GHG) emissions compared with gasoline. Field data from Kim et al. (2009) and from our own study suggest that geographic variability in the GHG emissions arising from corn production casts considerable doubt on the approach used in the RFS 2 to measure compliance with the 20% target. If regulators wish to require compliance of fuels with specific GHG emission reduction thresholds, then data from growing biomass should be disaggregated to a level that captures the level of variability in grain corn production and the application of life cycle assessment to biofuels should be modified to capture this variability

Novel transcriptomic panel identifies histologically active eosinophilic oesophagitis.

Eosinophilic oesophagitis (EoE) is characterised by symptoms of esophageal dysfunction and oesinophil tissue infiltration. The EoE Diagnostic Panel (EDP) can distinguish between active and non-active EoE using a set of 77 genes. Recently, the existence of distinct EoE variants featuring symptoms similar to EoE, such as oesophageal dysfunction but lacking eosinophil infiltration, had been determined. We used oesophageal biopsies from patients with histologically active (n=10) and non-active EoE (n=9) as well as from healthy oesophageal controls (n=5) participating in the Swiss Eosinophilic Esophagitis Cohort Study (SEECS) and analysed the gene expression profile in these biopsies by total RNA-sequencing (RNA-seq). Moreover, we employed the publicly accessible RNA-seq dataset (series GSE148381) as reported by Greuter et al, encompassing a comprehensive genomic profile of patients presenting with EoE variants. A novel, diagnostic gene expression panel that can effectively distinguish patients with histologically active conventional EoE from patients with EoE in histological remission and control individuals, and from three newly discovered EoE variants was identified. Histologically Active EoE Diagnostic Panel (HAEDP) consists of 53 genes that were identified based on differential expression between histologically active EoE, histological remission and controls (p≤0.05). By combining the HAEDP with EDP, we expanded our knowledge about factors that may contribute to the inflammation in EoE and improved our understanding of the underlying mechanisms of the disease. Conversely, we suggested a compact group of genes common to both HAEDP and EDP to create a reliable diagnostic tool that might enhance the accuracy of EoE diagnosis. We identified a novel set of 53 dysregulated genes that are closely associated with the histological inflammatory activity of EoE. In combination with EDP, our new panel might be a valuable tool for the accurate diagnosis of patients with EoE as well as for monitoring their disease course

Synthesizing a σ^z\hat{\sigma}_z spin-dependent force for optical, metastable, and ground state trapped-ion qubits

A single bichromatic field near-resonant to a qubit transition is typically used for $\hat{\sigma}_x$ or $\hat{\sigma}_y$ M{\o}lmer-S{\o}rensen type interactions in trapped ion systems. Using this field configuration, we present a novel scheme to synthesize a $\hat{\sigma}_z$ spin-dependent force instead; this basis change merely requires adjusting the beat-note frequency of the bichromatic field. We implement this scheme with a laser near-resonant to a quadrupole transition in $^{88}$Sr$^+$. We characterise its robustness to optical phase and qubit frequency offsets and demonstrate its versatility by entangling optical, metastable, and ground state qubits.Comment: O. B\u{a}z\u{a}van and S. Saner contributed equally to this wor

Breaking the entangling gate speed limit for trapped-ion qubits using a phase-stable standing wave

All laser-driven entangling operations for trapped-ion qubits have hitherto been performed without control of the optical phase of the light field, which precludes independent tuning of the carrier and motional coupling. By placing $^{88}$Sr$^+$ ions in a $\lambda=674$ nm standing wave, whose relative position is controlled to $\approx\lambda/100$, we suppress the carrier coupling by a factor of $18$, while coherently enhancing the spin-motion coupling. We experimentally demonstrate that the off-resonant carrier coupling imposes a speed limit for conventional traveling-wave M{\o}lmer-S{\o}rensen gates; we use the standing wave to surpass this limit and achieve a gate duration of $15\ \mu$s, restricted by the available laser power.Comment: S. Saner and O. B\u{a}z\u{a}van contributed equally to this wor