NIDANA VIVECHANA IN AKAALAJA JARA – REVIEW

Aging is defined as process of growing old, damage to cells, tissues and organs with the passage of time. Ayurveda being ancient system of medicine, clearly described about Jara and defined it as “Vayakrita slathamamsadi avastha” with other Lakshanas like Khalitya, Palitya, Smritinasha, Ksheenabala etc. In the blown up human civilization of present era and in the midst of increased various stress, improper diet, lack of exercise, low quality of food grain etc has adversely affected on the process of aging and may cause signs of premature aging, which is definitely an alarming sign and it may indicate the shorten lifespan. In Ayurveda prevention of disease has given utmost importance. To prevent any of the diseases one must know the causative factors properly, where Nidanaparivarjana is considered as first line of treatment in most of the diseases. “Everyone grows old”, Jara is an inescapable part of life but premature aging is an unnatural, untimely process. Prevention of this Akaalaja jara is possible only by understanding its Nidanas. There are so many internal and external factors which contribute for premature aging and this article is intended to explore those factors like Aharaja, Viharaja, Manasika nidanas to aim for targeted treatment

Influence of New Media on Travel Decision Making

Tourism, one of the largest industries in the world, has recorded  consistent  growth  since  the  end  of  Second World  War.  Travel  is  a  key  factor  in  the  process  of tourism, where the tourist is the main player as well as the  ultimate  consumer  of  the  products  and  services offered to him/her. A tourist‟s decision to travel is  by itself a complex process because there are many factors that influence the decision. The New media, which has emerged  in  the  wake  of  tremendous  advancements  in information  and  communication  technologies  is also influencing the decision making process in modern times. Here, an attempt has been done to examine the influence of new media in the various stages of decision making process and the role played by it. A questionnaire based survey was  undertaken  to  conduct  the  study  and  the analysis reveals various kinds of influences of new media

A study to assess the awareness and knowledge about the maternal nutrition and complications encountered by the antenatal mothers in the rural population

Background: Nutrition plays a vital role in life. Good nutrition is an important part of leading a healthy lifestyle. A healthy pregnancy diet will promote your baby's growth and development. The purpose of this study was to highlight the knowledge, attitude and practices of pregnant women regarding the healthy diet, psychological support, regular visits, danger signs and complications during pregnancy among mothers who visit our hospital along with different socio demographic factors.Methods: This study was conducted on 350 antenatal women from January 2016 to February 2017 at Tamil Nadu, India. A 24 point- 15 minutes’ questionnaire was designed about the knowledge, attitude and practice about the nutrition, danger signs and complications in pregnancy.Results: Around 98% of women were very clear that nutrition is necessary in pregnancy and 53% of them told that the quantity of food intake should be increased. Major source of knowledge about the nutrition was obtained from the family members (81%). The common danger sign was abdominal pain (61%) followed by bleeding per vaginum (22%). About 77% of mothers had an idea that minimum of 6-10 visit should be there in their antenatal period.Conclusions: This study emphasizes that health professionals should concentrate more in the nutritional values and the antenatal classes should be taken regarding the role of adequate nutrition, constituents and sources of balanced diet and the consequences of over and under nutrition

A Close Look Into the Financial Crisis and Financial Market Volatility-A Risk Management Perspective

The global financial crisis which was compared to great depression of the 1930’s surfaced with the subprime mortgage sector in the US in August 2007, this metamorphosed into a global financial crisis in September 2008 followed by the collapse of Lehman Brothers. The present study brings a comparison of the present financial crisis with the great depression of 1930’s and explains how the present crisis is different from great depression. Further the study ponders upon the impact of global crisis on financial markets. Key Words: Great depression, financial markets, EME”s, CDO’s, Financial Crisi

Cropping duration and non-rhizomorphic mycelial phenotype of Pleurotus djamor woody1 co-segregate in the hybrid progenies

Crop duration of the cultivated Pleurotus spp. is 45 to 50 days. P. djamor isolate woody-1 was collected as natural selection and was found to be short cropping duration variety with total cropping duration of 30 days but it is less palatable. It produced very thin, loose and non-rhizomorphic mycelia appearing light white color. Whereas, other commercial Pleurotus varieties such as P. florida and P. djamor MDU1 are long crop duration varieties and palatable producing thick, compact and rhizomorphic mycelia with bright white color. Co-segregation of non-rhizomorphic mycelial phenotype and short cropping duration trait of P. djamor woody- 1 in hybrid progenies was evaluated. Hybrid strains viz., H2W12 and H2W14 have thin, loose and non-rhizomorphic mycelium and they produced primordia in 9-10 days after spawning with total cropping duration of 29-32 days. Whereas, hybrid strain namely Pf1W2 has thick, compact and rhizomorphic mycelial phenotype and it produced primordia in 20 days after spawning with the total cropping duration of 47 days. This study indicated that genes governing short cropping duration and non-rhizomorphic mycelial pattern were tightly linked and co-segregated in the progenies. Thus, non-rhizomorphic mycelial phenotype of P. djamor woody1 can be used as a phenotypic marker for selection of hybrid cultivar having short cropping duration with other desired agronomic traits in future breeding strategy

L-deprenyl attenuates the rotenone-induced dopaminergic neurotoxicity: experimental evidences in rats

Parkinson disease (PD) is progressive neurological disorder because of massive degeneration of nigrostriatal dopaminergic neurons. The pathogenesis of PD is unknown, but considerable evidence suggests multifactorial factors including genetic, mitochondrial dysfunction, oxidative stress, excitotoxicity, calcium cytotoxicity, environmental factors and apoptosis. We investigated the role of oxidative damage produced by intranigral infusion of a potent mitochondrial complex-I inhibitor, rotenone and studied the neuroprotective effects with a well-known antiparkinsonian drug L-deprenyl in rats. Unilateral stereotaxic intranigral infusion of rotenone 6 lg caused significant decrease in dopamine levels. L-deprenyl (10 mg/kg) treatment significantly attenuated the DA depletion caused by rotenone. Parallely, a significant decrease in the concentration of GSH was also observed in the SN was reverted by L-deprenyl treatment. L-deprenyl significantly attenuated the rotenone-induced decrease in tyrosine hydroxylase immunoreactivity in striatum. The results suggest that L-deprenyl can rescue the dopaminergic neurons from the rotenone mediated neurodegeneration in this experimental animal model

Early postoperative outcomes of dunking pancreatojejunostomy

Background: There is no gold standard method for pancreatico-enteric reconstruction.  In our department, dunking pancreatojejunostomy (DPJ) and Duct to mucosa PJ technique are done as per surgeon’s choice.  In this study, authors evaluate the early postoperative outcomes following DPJ based on ISGPS (2007).Methods: A Retrospective analysis of prospectively collected data from January 2008 to December 2015. Detailed information on these patients was maintained on a prospectively held computerized database. Routine drain amylase estimations are being done on POD 3and 5 for all patients undergoing pancreatic resections and on all subsequent days if output is suggestive of pancreatic fistula. Details of patients who have undergone pancreatic resection with duct to mucosa type of pancreato-intestinal anastomosis during the same period (64 patients) were also collected prospectively and analysed. DPJ and Duct to mucosa groups were not comparable with respect to age, duct size, pancreatic gland texture and co-morbidities. Hence direct comparison between the two groups has not been carried out.Results: A total of 75 of 139 pancreatic resections with pancreatointestinal anastomosis who had dunking PJ and fulfilled the study criteria were analysed; none were excluded for analysing early outcomes. 19 out of 75 (25.5%) developed grade ‘A’ POPF, five out of 75 (6.6%) developed Grade ‘B’ POPF and three out of 75 (3.3%) developed Grade ‘C’ POPF. 20 out of 75 (26.6%) had grade ‘A’ DGE, five out of 75 (6.6%) had grade ‘B’ DGE. PPH occurred in four out of 75 (5.3%), two out of four were early PPH, one was managed by coiling and other by re-laparotomy, two were late PPH both managed by coiling of the pseudo aneurysms. There was no 30-day mortality.Conclusions: Dunking (Invagiantion) pancreatojejunostomy has accepatable early outcomes with clinically significant/relevant postoperative pancreatic fistula rates of Grade B (6.6%) and Grade C (4%), delayed gastric emptying (33.2%) and post pancreatic hemorrhage (5.3%) rates. The outcomes are comparable with Duct-to-mucosa PJ mentioned in literature