The Large-Scale, Authentic Assessment of Listening and Speaking as Interactive Communication: Issues in Reliability

In this article we discuss reliability issues in the large-scale assessment of speech communication through authentic or performance techniques used recently in Saskatchewan. New performance-based approaches enable educators to evaluate the integrated, interpersonal communication skills of large populations of students, thereby modeling best professional practice. We conclude, however, that decentralized teacher rating approaches do not yet demonstrate sufficient reliability to enable public officials to use the results for high-stakes testing purposes.Dans cet article, nous discutons de questions de fiabilité dans réévaluation à grande échelle de la communication verbale par le biais de techniques authentiques (ou basées sur la performance) employées en Saskatchewan. De nouvelles approches reposant sur la performance permettent aux enseignants d'évaluer les compétences communicatives intégrées et interpersonnelles de grandes populations d'élèves, reflétant ainsi les meilleures stratégies pédagogiques. Nous concluons toutefois que les approches impliquant une évaluation décentralisée ne s'avèrent pas encore suffisamment fiables pour que les fonctionnaires se servent des résultats dans des contextes ou l'enjeu est considérable

Marked periodicity in reproduction of the Panjab Freshwater Algae

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Some peculiarities in conjugation in a new Himalayan species of Zygnema

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A critical review of some recently created new species of Indian Zygnemales

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Endoscopic Management of an Internal Laryngopyocele Presenting with Acute Airway Obstruction

Statement of Problem. Laryngocele is a rare laryngeal disease, where there is an abnormal dilatation of the saccule of the laryngeal ventricle. It can either be internal or external, and a laryngopyocele is a rare complication of this anomaly. Internal laryngopyoceles can prove difficult to manage, as they often present with airway compromise. Method of Study. Case Report. Results. We present a case of a laryngopyocele that was successfully managed with suspension laryngoscopy and endoscopic marsupialisation and resection. To our knowledge, this is the first such case described in the literature. Conclusions. Surgical drainage of a laryngopyocele via the external approach is well documented in the literature. We feel that endoscopic resection of laryngopyoceles in an emergency situation is a viable alternative and also prevents the associated surgical morbidity

Implications of texture 4 zero lepton mass matrices for U_{e3}

Lepton mass matrices similar to texture 4 zero quark mass matrices, known to be quite successful in explaining the CKM phenomenology, have been considered for finding the mixing matrix element U_{e3} (\equiv s_{13}) respecting the CHOOZ constraint, with s_{12} and \Delta m_{12}^2 constrained by SNP and s_{23} and \Delta m_{23}^2 constrained by ANP. Taking charged lepton mass matrix M_l to be diagonal, we find that the ranges of s_{13} corresponding to different SNP solutions very well include the corresponding values of s_{13} found by Akhmedov et al. by considering neutrino mass matrix M_{\nu} with no texture zeros. Considering M_l and M_{\nu} both to be real and non-diagonal, s_{13} ranges for the four SNP solutions come out to be: \sim 0-0.19 (LMA), 0.038-0.093 (SMA), 0.042-0.095 (LOW), 0.038-0.096 (VO) which remain of the same order when M_l and M_{\nu} are considered to be complex and non-diagonal.Comment: 13 pages, LaTe

Expression of Epstein–Barr Virus–Encoded Small RNA (by the EBER-1 Gene) in Liver Specimens from Transplant Recipients with Post-Transplantation Lymphoproliferative Disease

Epstein-Barr virus (EBV)—associated post-transplantation lymphoproliferative disease (PTLD) develops in 1 to 10 percent of transplant recipients, in whom it can be treated by a reduction in the level of immunosuppression. We postulated that the tissue expression of the small RNA transcribed by the EBER-1 gene during latent EBV infection would identify patients at risk for PTLD. We studied EBER-1 gene expression in liver specimens obtained from 24 patients 2 days to 22 months before the development of PTLD, using in situ hybridization with an oligonucleotide probe. Control specimens were obtained from 20 recipients of allografts with signs of injury due to organ retrieval, acute graft rejection, or viral hepatitis in whom PTLD had not developed 9 to 71 months after the biopsy. Of the 24 patients with PTLD, 17 (71 percent) had specimens in which 1 to 40 percent of mononuclear cells were positive for the EBER-1 gene. In addition, 10 of these 17 patients (59 percent) had specimens with histopathological changes suggestive of EBV hepatitis. In every case, EBER-1—positive cells were found within the lymphoproliferative lesions identified at autopsy. Only 2 of the 20 controls (10 percent) had specimens with EBER-1—positive cells (P<0.001), and such cells were rare. EBER-1 gene expression in liver tissue precedes the occurrence of clinical and histologic PTLD. The possibility of identifying patients at risk by the method we describe here and preventing the occurrence of PTLD by a timely reduction of immunosuppression needs to be addressed by future prospective studies. (N Engl J Med 1992;327:1710–4.), POST-TRANSPLANTATION lymphoproliferative disease (PTLD), either polyclonal or monoclonal, complicates the clinical course of 1 to 10 percent of organ-transplant recipients.123 Immunohistochemical studies have demonstrated that the lymphoid cells within the lesions of PTLD almost invariably contain Epstein–Barr virus (EBV), primarily in a state of latent infection.4,5 The EBER-1 gene is expressed early during latent EBV infection and codes for a small messenger RNA (mRNA) expressed at up to 107 copies per cell.6 We and others have previously demonstrated the value of the detection of EBER-1 RNA for identifying EBV-infected cells in formalin-fixed paraffin-embedded tissues.7,8 In the current investigation, we used… © 1992, Massachusetts Medical Society. All rights reserved

Increasing the acceptability and rates of organ donation among minority ethnic groups: a programme of observational and evaluative research on Donation, Transplantation and Ethnicity (DonaTE)

Background: Black, Asian and minority ethnic (BAME) groups have a high need for organ transplantation but deceased donation is low. This restricts the availability of well-matched organs and results in relatively long waiting times for transplantation, with increased mortality risks. Objective: To identify barriers to organ donor registration and family consent among the BAME population, and to develop and evaluate a training intervention to enhance communication with ethnic minority families and identify impacts on family consent. Methods: Three-phase programme comprising (1) community-based research involving two systematic reviews examining attitudes and barriers to organ donation and effective interventions followed by 22 focus groups with minority ethnic groups; (2) hospital-based research examining staff practices and influences on family consent through ethics discussion groups (EDGs) with staff, a study on intensive care units (ICUs) and interviews with bereaved ethnic minority families; and (3) development and evaluation of a training package to enhance cultural competence among ICU staff. Setting: Community focus group study in eight London boroughs with high prevalence of ethnic minority populations. Hospital studies at five NHS hospital trusts (three in London and two in Midlands). Participants: (1) Community studies: 228 focus group participants; (2) hospital studies: 35 nurses, 28 clinicians, 19 hospital chaplains, 25 members of local Organ Donation Committees, 17 bereaved family members; and (3) evaluation: 66 health professionals. Data sources: Focus groups with community residents, systematic reviews, qualitative interviews and observation in ICUs, EDGs with ICU staff, bereaved family interviews and questionnaires for trial evaluation. Review methods: Systematic review and narrative synthesis. Results: (1) Community studies: Organ Donor Register – different ethnic/faith and age groups were at varying points on the ‘pathway’ to organ donor registration, with large numbers lacking knowledge and remaining at a pre-contemplation stage. Key attitudinal barriers were uncertainties regarding religious permissibility, bodily concerns, lack of trust in health professionals and little priority given to registration, with the varying significance of these factors varying by ethnicity/faith and age. National campaigns focusing on ethnic minorities have had limited impact, whereas characteristics of effective educational interventions are being conducted in a familiar environment; addressing the groups’ particular concerns; delivery by trained members of the lay community; and providing immediate access to registration. Interventions are also required to target those at specific stages of the donation pathway. (2) Hospital studies: family consent to donation – many ICU staff, especially junior nurses, described a lack of confidence in communication and supporting ethnic minority families, often reflecting differences in emotional expression, faith and cultural beliefs, and language difficulties. The continuing high proportion of family donation discussions that take place without the collaboration of a specialist nurse for organ donation (SNOD) reflected consultants’ views of their own role in family consent to donation, a lack of trust in SNODs and uncertainties surrounding controlled donations after circulatory (or cardiac) death. Hospital chaplains differed in their involvement in ICUs, reflecting their availability/employment status, personal interests and the practices of ICU staff. (3) Evaluation: professional development package – a digital versatile disk-based training package was developed to promote confidence and skills in cross-cultural communication (available at: www.youtube.com/watch?v=ueaR6XYkeVM&feature=youtu.be). Initial evaluation produced positive feedback and significant affirmative attitudinal change but no significant difference in consent rate over the short follow-up period with requirements for longer-term evaluation. Limitations: Participants in the focus group study were mainly first-generation migrants of manual socioeconomic groups. It was not permitted to identify non-consenting families for interview with data regarding the consent process were therefore limited to consenting families. Conclusions: The research presents guidance for the effective targeting of donation campaigns focusing on minority ethnic groups and provides the first training package in cultural competence in the NHS. Future work: Greater evaluation is required of community interventions in the UK to enhance knowledge of effective practice and analysis of the experiences of non-consenting ethnic minority families. Funding: The National Institute for Health Research Programme Grants for Applied Research programme