Water trees diagnostic of extruded underground cables: a case study in Saudi Arabia eastern province

In this paper, different electrical diagnostic techniques reported in the literature to predict the condition of extruded underground power cables are reviewed. Two of these techniques, namely the DC leakage current method and the DC conductivity method are applied to 14 underground cable samples rated between 15 kV and 69 kV collected from the Eastern Province of the Kingdom of Saudi Arabia. For this purpose, a setup has been constructed at the High Voltage Laboratory of King Fahd University of Petroleum & Minerals, Dhahran-Saudi Arabia. The results obtained show a correlation between the DC leakage current and the conductivity testing and the presence of water trees in the insulation material of cables. Samples suspected to have water trees are examined using the microscopic testing of the insulating material. The results obtained are in agreement with the electrical testing findings

Analysis of water trees in underground HV cables using the KFUPMmicro-PIXE facility

Scanning with the micro-PIXE technique was employed to analyze water trees in the XLPE insulation of a field-aged underground HV cable. X-ray spectra of bow tie and vented water trees, the inner and outer semiconductive compounds, and an insulation spot free from any water tree were acquired. Simultaneously, two-dimensional elemental distribution profiles across the water trees were also measured. Various trace element impurities were identified in the analyzed spots and their possible sources are suggested. Differences in elemental distribution profiles in the scanned areas were observed and have been discussed on the basis of the mechanism of incorporation of these elements into the insulation. This study demonstrates the effectiveness of the micro-PIXE facility available in this laboratory in analyzing water trees in underground power cable

Analysis of water trees in underground HV cables using the KFUPMmicro-PIXE facility

Scanning with the micro-PIXE technique was employed to analyze water trees in the XLPE insulation of a field-aged underground HV cable. X-ray spectra of bow tie and vented water trees, the inner and outer semiconductive compounds, and an insulation spot free from any water tree were acquired. Simultaneously, two-dimensional elemental distribution profiles across the water trees were also measured. Various trace element impurities were identified in the analyzed spots and their possible sources are suggested. Differences in elemental distribution profiles in the scanned areas were observed and have been discussed on the basis of the mechanism of incorporation of these elements into the insulation. This study demonstrates the effectiveness of the micro-PIXE facility available in this laboratory in analyzing water trees in underground power cable

Water trees diagnostic of extruded underground cables: a case study in Saudi Arabia eastern province

In this paper, different electrical diagnostic techniques reported in the literature to predict the condition of extruded underground power cables are reviewed. Two of these techniques, namely the DC leakage current method and the DC conductivity method are applied to 14 underground cable samples rated between 15 kV and 69 kV collected from the Eastern Province of the Kingdom of Saudi Arabia. For this purpose, a setup has been constructed at the High Voltage Laboratory of King Fahd University of Petroleum & Minerals, Dhahran-Saudi Arabia. The results obtained show a correlation between the DC leakage current and the conductivity testing and the presence of water trees in the insulation material of cables. Samples suspected to have water trees are examined using the microscopic testing of the insulating material. The results obtained are in agreement with the electrical testing findings

Microanalytical Investigations of Gold-Bearing Rocks from the An Najadi Region in Saudi Arabia

The Proton Induced X-ray Emission technique with a scanning microbeam (micro-PIXE) and Scanning Electron Microscopy (SEM) were employed to study gold-bearing rocks from the An Najadi and adjacent regions situated within the exposed northeastern part of the Arabian Shield. These microanalytical investigations, together with routine petrological and ore microscopic studies, demonstrated the presence of important partitioning of major minerals and trace elements in several samples. These measurements also revealed microstructural features including brecciation within quartz grains and metal concentrations within these fracture-controlled micro-conduits. Results showed promise in terms of using distinctive geochemical signatures for ore body recognition. Of particular interest to this study is the presence of an identifiable geochemical trend pertaining to As, Ti, Zn, Cu, Fe and Au. Overall geochemical and petrological data indicate an epithermal mineralization phenomenon for the metal deposits in the An Najadi regions. Mineralization not only postdated brecciation but also followed the regional structural grain of this area

Measurement and simulation of the neutron response of the Nordball liquid scintillator array

The response of the liquid scintillator array Nordball to neutrons in the energy range 1.5 < T_n < 10 MeV has been measured by time of flight using a 252Cf fission source. Fission fragments were detected by means of a thin-film plastic scintillator. The measured differential and integral neutron detection efficiencies agree well with predictions of a Monte Carlo simulation of the detector which models geometry accurately and incorporates the measured, non-linear proton light output as a function of energy. The ability of the model to provide systematic corrections to photoneutron cross sections, measured by Nordball at low energy, is tested in a measurement of the two-body deuteron photodisintegration cross section in the range E_gamma=14-18 MeV. After correction the present 2H(gamma,n)p measurements agree well with a published evaluation of the large body of 2H(gamma,p)n data.Comment: 20 pages 10 figures, submitted Nucl. Instr. Meth.

Plasma therapy in atypical haemolytic uremic syndrome: lessons from a family with a factor H mutation

Whilst randomised control trials are undoubtedly the best way to demonstrate whether plasma exchange or infusion alone is the best first-line treatment for patients with atypical haemolytic uremic syndrome (aHUS), individual case reports can provide valuable information. To that effect, we have had the unique opportunity to follow over a 10-year period three sisters with aHUS associated with a factor H mutation (CFH). Two of the sisters are monozygotic twins. A similar natural evolution and response to treatment would be expected for the three patients, as they all presented with the same at-risk polymorphisms for CFH and CD46 and no identifiable mutation in either CD46 or CFI. Our report of different modalities of treatment of the initial episode and of three transplantations and relapses in the transplant in two of them, strongly suggest that intensive plasma exchange, both acutely and prophylactically, can maintain the long-term function of both native kidneys and allografts. In our experience, the success of plasma therapy is dependent on the use of plasma exchange as opposed to plasma infusion alone, the prolongation of daily plasma exchange after normalisation of haematological parameters followed by prophylactic plasma exchange, the use of prophylactic plasma exchange prior to transplantation and the use of prophylactic plasma exchange at least once a week posttransplant with immediate intensification of treatment if there are any signs of recurrence

Correlation between p38 mitogen-activated protein kinase and human telomerase reverse transcriptase in sarcomas

<p>Abstract</p> <p>Background</p> <p>One of the major components of telomerase is the human telomerase reverse transcriptase (hTERT) as the catalytic protein. hTERT mRNA expression are reported to be associated with prognosis and tumor progression in several sarcomas. However, there is no clear understanding of the mechanisms of hTERT in human sarcomas. Recent studies have suggested that signals transmitted through p38 mitogen-activated protein kinase (MAPK) can increase or decrease hTERT transcription in human cells. The purpose of this study was to analyse the correlation between p38 MAPK and hTERT in sarcoma samples.</p> <p>Methods</p> <p>We investigated 36 soft tissue malignant fibrous histiocytomas (MFH), 24 liposarcomas (LS) and 9 bone MFH samples for hTERT and p38 MAPK expression. Quantitative detection of hTERT and p38 MAPK was performed by RT-PCR.</p> <p>Results</p> <p>There was a significant positive correlation between the values of hTERT and p38 MAPK in all samples (r = 0.445, p = 0.0001), soft tissue MFH (r = 0.352, p = 0.0352), LS (r = 0.704, p = 0.0001) and bone MFH samples (r = 0.802, p = 0.0093). Patients who had a higher than average expression of p38 MAPK had a significantly worse prognosis than other patients (p = 0.0036).</p> <p>Conclusions</p> <p>p38 MAPK may play a role in up-regulation of hTERT, and therefore, p38 MAPK may be a useful marker in the assessment of hTERT and patients' prognosis in sarcomas.</p

Amplification of telomerase (hTERT) gene is a poor prognostic marker in non-small-cell lung cancer

Telomerase reactivation is a hallmark of human carcinogenesis. Increased telomerase activity may result from gene amplification and/or overexpression. This study evaluates the prognostic value of hTERT gene amplification and mRNA overexpression in 144 resectable non-small-cell lung cancer (NSCLC) specimens. The hTERT gene copy number was assessed by quantitative polymerase chain reaction (qPCR) on laser-capture microdissected tumour cells of 81 tumours, and by fluorescence in situ hybridisation (FISH) on a subset of 59 tumours. hTERT mRNA level was determined by reverse transcription (RT)–qPCR in 130 tumours. In total, 57% of (46 out of 81) primary NSCLC specimens demonstrated hTERT amplification, which was significantly more common (P<0.001) in adenocarcinoma (30 out of 40) than in squamous cell carcinoma (13 out of 37). The hTERT mRNA overexpression was noted in 74% (94 out of 130) of tumours; it was more frequent in squamous cell than in adenocarcinoma (87 vs 68%, P=0.03). Overexpression was significantly associated with amplification (P=0.03), especially in adenocarcinoma. The hTERT gene amplification was prognostic for shorter recurrence-free survival (hazard ratio=2.16, P=0.03). These data indicate that gene amplification is an important mechanism for hTERT overexpression in lung adenocarcinoma and is an independent poor prognostic marker for disease-free survival in NSCLC