Potassium 2-oxoimidazolidine-1,3-diide: An effective and new catalyst for the grinding synthesis of (1H-indol-3-yl)methyl-2H-indan-1,3-diones

Potassium 2-oxoimidazolidine-1,3-diide (POImD) is easily used as an efficient and recyclable catalyst for the synthesis of 2H-indene-1,3-dione derivatives by a reaction between indoles, 2H-indene-1,3-dione and aldehydes at room temperature. All reactions are performed in humid POImD in high to excellent yield during short reaction time. Further, the catalyst can be reused and recovered for several times without loss of activity.               KEY WORDS: 1,3-Indandione, Indole, POImD, One pot reaction Bull. Chem. Soc. Ethiop. 2018, 32(2), 399-405.DOI: https://dx.doi.org/10.4314/bcse.v32i2.1

Fe+3-montmorillonite K10: As an effective and reusable catalyst for the synthesis of 3,4-dihydropyrimidin-2(1H)-ones and –thiones

In this study, a novel, clean, convenient, appropriate and environmentally benign route to dihydropyrimidinone and thione derivatives has been developed using the reaction between various benzaldehydes, urea or thiourea, and ethyl acetoacetate in the presence of Fe+3-montmorillonite K10 under grind condition. The present methodology has several advantages such as simple work-up, solvent-free conditions, environmental friendliness and shorter reaction time along with high yields. Several aromatic aldehydes carrying either electron-releasing or electron-withdrawing substituents in the ortho and para positions were tested in this reaction. Another important feature of this procedure is the survival of a variety of functional groups under the reaction conditions. All of synthesized compounds were characterized by IR, 1HNMR, 13CNMR and elemental analyses

Grinding technique for the tandem synthesis of bis coumarinyl methanes using [BDBDMIm]Br-CAN

3,3-(Butane-1,4-diyl)bis(1,2-dimethyl-1H-imidazole-3-ium)bromide ([BDBDMIm]Br) is easily used as an efficient and recyclable ionic liquid for the synthesis of bis coumarinyl methanes in the presence of a catalytic amount of ceric ammonium nitrate (CAN) under grinding. All reactions are performed in the absence of solvent in excellent yield during short reaction time. Furthermore, the ionic liquid can be reused and recovered for several times without loss of activity. This method provides several advantages such as simple work-up, environmental friendliness and shorter reaction time along with high yields. All of synthesized compounds were characterized by infrared spectroscopy, 1H and 13C nuclear magnetic resonance spectroscopy and elemental analyses