15,629 research outputs found
More than just friends? Facebook, disclosive ethics and the morality of technology
Social networking sites have become increasingly popular destinations for people wishing to chat,
play games, make new friends or simply stay in touch. Furthermore, many organizations have
been quick to grasp the potential they offer for marketing, recruitment and economic activities.
Nevertheless, counterclaims depict such spaces as arenas where deception, social grooming and
the posting of defamatory content flourish. Much research in this area has focused on the ends to
which people deploy the technology, and the consequences arising, with a view to making policy
recommendations and ethical interventions. In this paper, we argue that tracing where morality
lies is more complex than these efforts suggest. Using the case of a popular social networking site,
and concepts about the morality of technology, we disclose the ethics of Facebook as diffuse and
multiple. In our conclusions we provide some reflections on the possibilities for action in light of
this disclosure
The Relationship between Resilience and Body Image in College Women
Possessing a negative body image is associated with unhealthy eating habits and eating disorders in college women and has been linked to depression and negative feelings of self worth. Limited research exists on protective factors that have the potential to mitigate body image dissatisfaction. This paper examines the relationship of resilience to body image dissatisfaction in college women. Female, undergraduate college students were studied using previously validated measures. Results indicate that increased resilience is associated with improved body image
Human Papillomavirus (HPV) Vaccine: Attitudes, Behaviors, and Beliefs of At-Risk Women
Cervical cancer is primarily caused by human papillomavirus (HPV) and is the second most common cause of cancer-related mortality among women. Female college students may be at risk for contracting HPV based on their sexual behavior. Following the release of the HPV vaccine, GardasilÂź, this cross-sectional study was developed to (1) determine awareness of HPV and GardasilÂź, (2) assess attitudes, behaviors, and beliefs about the HPV vaccine, and (3) identify information sources that female college students are accessing. Female college students voluntarily completed a self-administered questionnaire. Statistical analyses included descriptive statistics, Pearsonâs correlations and paired sample t-tests. Sexually active respondents would recommend the HPV vaccine to others and disagreed that vaccination would encourage risky sexual behavior. Correlations were identified on how self-reported knowledge influenced attitudes, behaviors, and beliefs regarding the HPV vaccine. These findings should assist in developing integrated public health education efforts for HPV vaccination that are targeted towards this at-risk population
Teaching Physics Using Virtual Reality
We present an investigation of game-like simulations for physics teaching. We
report on the effectiveness of the interactive simulation "Real Time
Relativity" for learning special relativity. We argue that the simulation not
only enhances traditional learning, but also enables new types of learning that
challenge the traditional curriculum. The lessons drawn from this work are
being applied to the development of a simulation for enhancing the learning of
quantum mechanics
A 100 GHz coplanar strip circuit tuned with a sliding planar backshort
A means of mechanically altering the electrical length of a planar transmission line would greatly enhance the use of integrated circuit technology at millimeter and submillimeter wavelengths. Such a mechanically adjustable planar RF tuning element, successfully demonstrated at 100 GHz, is described here. It consists of a thin metallic sheet, with appropriately sized and spaced holes, which slides along on top of a dielectric-coated coplanar-strip transmission line. Multiple RF reflections caused by this structure add constructively, resulting in a movable RF short circuit, with |s11|≫APX=/-0.3 dB, which can be used to vary the electrical length of a planar tuning stub. The sliding short is used here to produce a 2-dB improvement in the response of a diode detector. This tuning element can be integrated with planar circuits to compensate for the effect of parasitic reactance inherent in various devices including semiconductor diodes and superconductor-insulator-superconductor (SIS) junctions
Epac and the high affinity rolipram binding conformer of PDE4 modulate neurite outgrowth and myelination using an in vitro spinal cord injury model
<b>Background and Purpose</b><p></p>
cAMP and pharmacological inhibition of PDE4, which degrades it, are promising therapeutic targets for the treatment of spinal cord injury (SCI). Using our previously described in vitroâ
SCI model, we studied the mechanisms by which cAMP modulators promote neurite outgrowth and myelination using enantiomers of the PDE4-specific inhibitor rolipram and other modulators of downstream signalling effectors.<p></p>
<b>Experimental Approach</b><p></p>
Rat mixed neural cell myelinating cultures were cut with a scalpel and treated with enantiomers of the PDE4-specific inhibitor rolipram, Epac agonists and PKA antagonists. Neurite outgrowth, density and myelination were assessed by immunocytochemistry and cytokine levels analysed by qPCR.<p></p>
<b>Key Results</b><p></p>
Inhibition of the high-affinity rolipram-binding state (HARBS), rather than the low-affinity rolipram binding state (LARBS) PDE4 conformer promoted neurite outgrowth and myelination. These effects were mediated through the activation of Epac and not through PKA. Expression of the chemokine CXCL10, known to inhibit myelination, was markedly elevated in astrocytes after Rho inhibition and this was blocked by inhibition of Rho kinase or PDE4.<p></p>
<b>Conclusions and Implications</b><p></p>
PDE4 inhibitors targeted at the HARBS conformer or Epac agonists may provide promising novel targets for the treatment of SCI. Our study demonstrates the differential mechanisms of action of these compounds, as well as the benefit of a combined pharmacological approach and highlighting potential promising targets for the treatment of SCI. These findings need to be confirmed in vivo
Understanding the ECG part 1: anatomy and physiology
This first article in a series on 12-lead ECG interpretation explores the importance of the ECG as a diagnostic tool, discusses the anatomy and physiology underpinning cardiac electrical activity, and introduces the basic waveforms seen on the ECG
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Exploring the democratic potential of online social networking: The scope and limitations of e-participation
Copyright © 2012 by the Association for Information Systems.The availability and promise of social networking technologies with their perceived open philosophy has increasingly inspired citizens around the world to participate in political activity on the Web. Recent examples range from opposing public policies, such as government funding cuts, to organizing revolutionary social movements, such as those in the Middle East and North Africa. Although online spaces create remarkable opportunities for various forms of political action, there are concerns over the power of existing institutions to control and even censor such interaction spaces. The objective of this article is to draw together different insights on the online engagement phenomenon, highlighting both its potential and limitations as a mechanism for fostering democratic debate and influencing policy making. We examine recent examples from Europe, the Middle East and Latin America. Finally, we summarize the implications of our work and outline directions for further research
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