234 research outputs found

    Competição nacional de progênies e linhagens de cafeeiros, com resistência à ferrugem, de seleções do Procafé: resultados iniciais em São Domingos das Dores - MG.

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    No presente trabalho apresenta-se os resultados iniciais do ensaio em São Domingos das Dores, a 790 m de altitude, na Zona da Mata de Minas Gerais, com o objetivo de apresentar a capacidade produtiva inicial dos materiais em teste. Na medida da evolução das safras nos ensaios e da sua tabulação pretende-se agrupar os resultados para uma avaliação conjunta das diferentes localidades

    Seleção de plantas matrizes de cafeeiros da cultivar siriema, com resistência à ferrugem e ao bicho-mineiro e resultados iniciais de produtividade em clones.

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    Estudo das características de produtividade e qualidade dos frutos nos 2 campos de seleção avaliando um maior número de safras, para observar e selecionar plantas matrizes, que mantiveram vigor e resistência e boas características produtivas

    Differential regulation of PGC-1α expression in rat liver and skeletal muscle in response to voluntary running

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    <p>Abstract</p> <p>Background</p> <p>The beneficial actions of exercise training on lipid, glucose and energy metabolism and insulin sensitivity appear to be in part mediated by PGC-1α. Previous studies have shown that spontaneously exercised rats show at rest enhanced responsiveness to exogenous insulin, lower plasma insulin levels and increased skeletal muscle insulin sensitivity. This study was initiated to examine the functional interaction between exercise-induced modulation of skeletal muscle and liver PGC-1α protein expression, whole body insulin sensitivity, and circulating FFA levels as a measure of whole body fatty acid (lipid) metabolism.</p> <p>Methods</p> <p>Two groups of male Wistar rats (2 Mo of age, 188.82 ± 2.77 g BW) were used in this study. One group consisted of control rats placed in standard laboratory cages. Exercising rats were housed individually in cages equipped with running wheels and allowed to run at their own pace for 5 weeks. At the end of exercise training, insulin sensitivity was evaluated by comparing steady-state plasma glucose (SSPG) concentrations at constant plasma insulin levels attained during the continuous infusion of glucose and insulin to each experimental group. Subsequently, soleus and plantaris muscle and liver samples were collected and quantified for PGC-1α protein expression by Western blotting. Collected blood samples were analyzed for glucose, insulin and FFA concentrations.</p> <p>Results</p> <p>Rats housed in the exercise wheel cages demonstrated almost linear increases in running activity with advancing time reaching to maximum value around 4 weeks. On an average, the rats ran a mean (Mean ± SE) of 4.102 ± 0.747 km/day and consumed significantly more food as compared to sedentary controls (<it>P </it>< 0.001) in order to meet their increased caloric requirement. Mean plasma insulin (<it>P </it>< 0.001) and FFA (<it>P </it>< 0.006) concentrations were lower in the exercise-trained rats as compared to sedentary controls. Mean steady state plasma insulin (SSPI) and glucose (SSPG) concentrations were not significantly different in sedentary control rats as compared to exercise-trained animals. Plantaris PGC-1α protein expression increased significantly from a 1.11 ± 0.12 in the sedentary rats to 1.74 ± 0.09 in exercising rats (<it>P </it>< 0.001). However, exercise had no effect on PGC-1α protein content in either soleus muscle or liver tissue. These results indicate that exercise training selectively up regulates the PGC-1α protein expression in high-oxidative fast skeletal muscle type such as plantaris muscle.</p> <p>Conclusion</p> <p>These data suggest that PGC-1α most likely plays a restricted role in exercise-mediated improvements in insulin resistance (sensitivity) and lowering of circulating FFA levels.</p
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