Role of Footing Embedment on Tunnel–Foundation Interaction

This technical note investigates the effect of footing embedment depth on tunnel-structure interaction using geotechnical centrifuge testing. A two-story framed building on separate footings, either resting directly on the surface or embedded in the soil, and subjected to tunneling induced displacements is modeled. Measurements of the displacements of the footings and underlying soil, ground deformations, and structural distortions are presented. Results show that footing embedment increases foundation differential settlements and horizontal displacements, thereby causing a greater level of distortion within the frame. Furthermore, the embedded footings result in a larger magnitude of ground displacements and shear strains of the soil. Finally, modification factors and relative stiffness parameters are presented, indicating a greater effect of the embedment on horizontal deformations than the angular distortion of the bays

Tunnel–framed building interaction: comparison between raft and separate footing foundations

This paper investigates the influence of the foundation configuration (raft or separate footings) on tunnel-soil-framed building interaction using geotechnical centrifuge testing. Tunnelling-induced soil movements and deformation fields, framed building displacements, and structure shear distortions (with associated modification factors) are illustrated. Framed building stiffness and footing bearing capacity are also evaluated experimentally. Results show that the foundation configuration plays an important role in determining the ground response to tunnelling, affecting soil displacement fields as well as the distribution of soil shear and volumetric strains. In particular, foundation settlements and differential horizontal displacements are larger for separate footings compared to raft foundations. The effects of building width, weight, and eccentricity (with respect to the tunnel) on foundation settlements and structural distortions is quantified for separate footings and contrasted against results for raft foundations. The modification factor of the maximum building shear distortion is linked to the relative soil-building shear stiffness; interestingly, for buildings with similar values of relative stiffness, the level of shear distortion within framed buildings is lower for separate footings than rafts

Tunneling-Induced Deformation of Bare Frame Structures on Sand: Numerical Study of Building Deformations

The paper compares the performance of two Finite Element Method approaches in reproducing the response of bare frame structures to tunneling in dry dense sand. A fully coupled approach, in which the tunnel, frame and soil are accounted for, is compared with a two-stage method incorporating simpler structural and soil models. The two approaches are validated against centrifuge test results of tunneling in sand beneath frames founded on either rafts or separate footings. Both approaches provide good estimates of displacements and distortions experienced by the frames provided that the soil-foundation interface and structural stiffness are correctly accounted for. The numerical models are also employed to extend the range of eccentric configurations investigated with centrifuge tests. The results demonstrate that shear deformations play an important role for all considered buildings, whereas only frames on separate footings are sensitive to horizontal ground movements. Finally, data are synthesized using modification factors and recently proposed relative stiffness terms

A Real-Time Space Debris Detection System for BIRALES

The ever increasing satellite population in near-Earth orbit has made the monitoring and tracking of cooperative and non-cooperative objects ever more important. Non-cooperative objects, or space debris, pose a threat to existing and future satellites as they cannot avoid potential collisions. Furthermore, the orbit of the smaller debris is often not actively monitored. As the population grows, the risk of a collision increases. Thus, various institutions around the world have been upgrading their space detection capabilities in order to better monitor the objects orbiting Earth down to a few centimetres in diameter. One of the latest such systems is the BIstatic RAdar for LEo Survey (BIRALES) space debris detection system based in Italy. The BIRALES system is a bistatic radar composed of a radio transmitter in Sardinia and the Medicina Northern Cross radio telescope near Bologna as the receiver. The backend of this system includes a digital beamformer able to synthetize 32 beams covering the instrument's Field of View (FoV). As a high-velocity object transits, its Doppler shift signature (or track) can be measured. Whilst a number of streak detection algorithms have been proposed for optical telescopes, the number of detection algorithms for high-speed objects for bistatic radars is limited. This work describes the detection algorithm used in the BIRALES space debris detection pipeline. The detection algorithm takes the beamformed, channelized data as input. Firstly, the data undergoes a number of pre-processing stages before the potential space debris candidates are identified. Secondly, the candidates are validated against a number of criteria in order to improve the detection quality. The algorithm was designed to process the incoming data across 32 beams in real-time. Initial validation results on known objects are positive and the system has been shown to reliably determine orbiting objects with minimal false positives

Copper-Triggered Aggregation of Ubiquitin

Neurodegenerative disorders share common features comprising aggregation of misfolded proteins, failure of the ubiquitin-proteasome system, and increased levels of metal ions in the brain. Protein aggregates within affected cells often contain ubiquitin, however no report has focused on the aggregation propensity of this protein. Recently it was shown that copper, differently from zinc, nickel, aluminum, or cadmium, compromises ubiquitin stability and binds to the N-terminus with 0.1 micromolar affinity. This paper addresses the role of copper upon ubiquitin aggregation. In water, incubation with Cu(II) leads to formation of spherical particles that can progress from dimers to larger conglomerates. These spherical oligomers are SDS-resistant and are destroyed upon Cu(II) chelation or reduction to Cu(I). In water/trifluoroethanol (80∶20, v/v), a mimic of the local decrease in dielectric constant experienced in proximity to a membrane surface, ubiquitin incubation with Cu(II) causes time-dependent changes in circular dichroism and Fourier-transform infrared spectra, indicative of increasing β-sheet content. Analysis by atomic force and transmission electron microscopy reveals, in the given order, formation of spherical particles consistent with the size of early oligomers detected by gel electrophoresis, clustering of these particles in straight and curved chains, formation of ring structures, growth of trigonal branches from the rings, coalescence of the trigonal branched structures in a network. Notably, none of these ubiquitin aggregates was positive to tests for amyloid and Cu(II) chelation or reduction produced aggregate disassembly. The early formed Cu(II)-stabilized spherical oligomers, when reconstituted in 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) liposomes and in POPC planar bilayers, form annular and pore-like structures, respectively, which are common to several neurodegenerative disorders including Parkinson's, Alzheimer's, amyotrophic lateral sclerosis, and prion diseases, and have been proposed to be the primary toxic species. Susceptibility to aggregation of ubiquitin, as it emerges from the present study, may represent a potential risk factor for disease onset or progression while cells attempt to tag and process toxic substrates