Physiology and biochemistry of reduction of azo compounds by Shewanella strains relevant to electron transport chain

Azo dyes are toxic, highly persistent, and ubiquitously distributed in the environments. The large-scale production and application of azo dyes result in serious environmental pollution of water and sediments. Bacterial azo reduction is an important process for removing this group of contaminants. Recent advances in this area of research reveal that azo reduction by Shewanella strains is coupled to the oxidation of electron donors and linked to the electron transport and energy conservation in the cell membrane. Up to date, several key molecular components involved in this reaction have been identified and the primary electron transportation system has been proposed. These new discoveries on the respiration pathways and electron transfer for bacterial azo reduction has potential biotechnological implications in cleaning up contaminated sites

PCN249 - Subjective Financial Burden Among German Cancer Patients - Relationship Of The Patients’ Economic Situation And Subjective Distress

Witte J, Mehlis K, Kudlich M, et al. PCN249 - Subjective Financial Burden Among German Cancer Patients - Relationship Of The Patients’ Economic Situation And Subjective Distress. In: Value in Health. Vol 20. Elsevier Science; 2017: A457

SPECT- and PET-based patient-tailored treatment in neuroendocrine tumors: a comprehensive multidisciplinary team approach.

The overexpression of somatostatin receptors on the tumor cell surface of neuroendocrine tumors (NETs) detected by multimodal functional imaging modalities such as SPECT and PET tracers constitutes a therapeutic option using targeting radiolabeled compounds. We will introduce the theranostic concept in general, explain in more detail its development in NETs, and discuss available SPECT and PET tracers regarding their potential for diagnostic imaging, visualization of target expression, and treatment tailoring. Moreover, we will discuss the currently available peptide receptor radionuclide therapy principles and compare them to previously published studies. Finally, we will iscuss which new concepts will most likely influence the theranostic treatment approach in NETs in the future

Financial implications of cancer. Empirical data and ethical aspects

Mehlis K, Witte J, Surmann B, et al. Financial implications of cancer. Empirical data and ethical aspects. In: Manz MG, ed. Abstractband für die Virtuelle Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, 09.–11. Oktober 2020: Abstracts. Oncology Research and Treatment . Vol 43. Basel: Karger; 2020: 21-22