141 research outputs found

    Rebrota de sorgo forrageiro fertilizado com dejetos de bovinos e adubo quĂ­mico.

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    Extraction of Citric Acid by Liquid Surfactant Membranes: Bench Experiments in Single and Multistage Operation

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    The extraction of citric acid by liquid surfactant membranes (LSM) was performed using A/O/A emulsions, composed of sodium acetate aqueous solutions (inner phase), mixtures of Alamine 336 and ECA 4360 dissolved in Exxsol D240/280 (membrane phase), and citric acid aqueous solutions (feed phase). Two factorial designs (25–1 and 23) were used to define suitable operating conditions, in a single stage, producing citric acid solutions at 0.25 g mL–1 from aqueous feed solutions at 0.10 g mL–1. The parameters investigated and the best operating conditions obtained were pH of the feed phase (pH = 1.5), surfactant (ws = 2 %) and carrier concentration in the membrane phase (wc = 20 %), stirring speed (v = 145 rpm), and permeation time (t = 10 minutes) upon the citric acid concentration in the inner and feed phases, and inner phase swelling. Under these conditions, an extraction greater than 50 % and swelling equal to 80 % were obtained. Use of recycled membranes as well as extraction in multiple stages was also evaluated. Experiments of recycling revealed that the membranes can be reused for at least three times with good performance. Extraction in multiple stages showed high efficiency for the citric acid separation (~100 %) after three steps of operation

    Telemedicine Critical Care-Mediated Mortality Reductions in Lower-Performing Patient Diagnosis Groups: A Prospective, Before and After Study

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    OBJECTIVES: Studies evaluating telemedicine critical care (TCC) have shown mixed results. We prospectively evaluated the impact of TCC implementation on risk-adjusted mortality among patients stratified by pre-TCC performance. DESIGN: Prospective, observational, before and after study. SETTING: Three adult ICUs at an academic medical center. PATIENTS: A total of 2,429 patients in the pre-TCC (January to June 2016) and 12,479 patients in the post-TCC (January 2017 to June 2019) periods. INTERVENTIONS: TCC implementation which included an acuity-driven workflow targeting an identified “lower-performing” patient group, defined by ICU admission in an Acute Physiology and Chronic Health Evaluation diagnoses category with a pre-TCC standardized mortality ratio (SMR) of greater than 1.5. MEASUREMENTS AND MAIN RESULTS: The primary outcome was risk-adjusted hospital mortality. Risk-adjusted hospital length of stay (HLOS) was also studied. The SMR for the overall ICU population was 0.83 pre-TCC and 0.75 post-TCC, with risk-adjusted mortalities of 10.7% and 9.5% (p = 0.09). In the identified lower-performing patient group, which accounted for 12.6% (n = 307) of pre-TCC and 13.3% (n = 1671) of post-TCC ICU patients, SMR decreased from 1.61 (95% CI, 1.21–2.01) pre-TCC to 1.03 (95% CI, 0.91–1.15) post-TCC, and risk-adjusted mortality decreased from 26.4% to 16.9% (p \u3c 0.001). In the remaining (“higher-performing”) patient group, there was no change in pre- versus post-TCC SMR (0.70 [0.59–0.81] vs 0.69 [0.64–0.73]) or risk-adjusted mortality (8.5% vs 8.4%, p = 0.86). There were no pre- to post-TCC differences in standardized HLOS ratio or risk-adjusted HLOS in the overall cohort or either performance group. CONCLUSIONS: In well-staffed and overall higher-performing ICUs in an academic medical center, Acute Physiology and Chronic Health Evaluation granularity allowed identification of a historically lower-performing patient group that experienced a striking TCC-associated reduction in SMR and risk-adjusted mortality. This study provides additional evidence for the relationship between pre-TCC performance and post-TCC improvement
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